USD 1.56067 billion
Report ID: SQMIG35G2036 | Region: Global | Published Date: November, 2022 | Pages: 157 | Tables: 126 | Figures: 67
Global 3D Cell Culture Market size was valued at USD 1.56067 billion in 2021, and it is expected to reach a value of USD 372.186 billion by 2028, at a CAGR of 13.4% over the forecast period (2022-2028).
The life sciences industry is witnessing a rapid change with the arrival of new technologies such as 3D cell culture. The introduction of this promising technology has transformed the field of tissue engineering, drug discovery, stem cell research, and cancer detection many more. The fast acceptance of 3D cell culture technology has led to a change in trends in both academic and industrial areas to modified research solutions and the use of cell culture in vivo-like models to comprehend cell behavior. This is driving the rising 3D Cell Culture Market need for better solutions in 3D cell culture.
In research that calls for in vivo model systems to examine the effects of a foreign substance upon bodily tissues and organs, 3D cultures are frequently used since they can accurately replicate the usual morphology and micro architecture of organs. Moreover, a significant number of research entities adopted 3-dimensional cell culture techniques due to the bio mimetic tissue constructs employed to produce 3D organotypic structures. Additionally, a new approach to conventional methods for treating Covid-19, cancer, and other clinical illnesses has emerged: using 3D tissue-engineered models. In comparison to 2D approaches, this also demonstrates significant promise in terms of offering a very straightforward and affordable in vitro tumor-host environment.
Global Market Size
USD 1.56067 billion
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The Global 3D Cell Culture Market is segmented based on Product, Application, End-User, and Region. Based on Product it is categorized into Scaffold-Based 3D cell culture, Scaffold-Free 3D cell culture, Microfluidics, and 3D Bioreactors. Based on Application it is categorized into Cancer Treatment, Stem Cell Research, Drug Discovery, and Regenerative Medicine. Based on End-user it is categorized into Biotechnology & Pharmaceutical Companies, Contract Research Laboratories, and Academic Institutes. Based on type, the market is segmented into hydrogel, ECM, hanging drop, bioreactor, microfluidics, and magnetic levitation. Based on the region it is categorized into North America, Europe, Asia-Pacific, South America, and MEA.
Analysis by Application
Based on application, the analysis of 3D Cell Culture is divided into drug discovery, cancer research, tissue engineering, and regenerative medicine. The cancer research segment ruled the 3D Cell Culture Market with a major revenue share of 24% in 2021. The use of spheroids as a model during the development of anti-cancer treatments pushes R&D in this segment. Furthermore, the use of 3D cellular models for the study of cancer biology in pre-clinical testing, and screening is expected to increase revenue growth in this segment.
A research study reported the progress of polysaccharide hydrogel 3D printed tumor models in January 2021, which can be used for screening of anticancer drugs. The researchers aimed at developing hydrogel, which completely duplicates the tumor microenvironment, showing appropriate biocompatibility, and printability. Such expansions lead to increased use of scaffold-based techniques for cancer.
Stem cell research is likely to record the fastest CAGR from 2022 to 2028. An increase in the use of 3D cell culture platforms for regenerative medicine is expected to push the growth in the segment. Histogen, Inc. engaged in the development of regenerative medicine in January 2020, merged with Conatus Pharmaceuticals Inc. for the final demonstration of a robust channel of unique clinical trials, inclusive of an extracellular matrix scaffold technique for the treatment of conditions related to articular cartilage.
Analysis by End-User
The End-users for 3D cell culture comprised Biotechnology & Pharmaceutical Companies, Contract Research Laboratories, and Academic Institutes. Where the biotechnology and pharmaceutical industries generated a major revenue share of over 46% in 2021. 3D cell cultures are a better fit for drug discovery and development, thereby driving the demand in the forecast period.
Reasons such as the immediate need for rapid and accurate diagnostic services and the advantages of 3D models over 2D models in giving detailed physiological information, boost the hospitals and diagnostic centers growth. Diagnostic centers, such as Kiyatec that are actively involved in giving 3D models for advanced research, are expected to boost the segment growth in the forecast period. Industrial laboratories and Academic institutes are also predicted to contribute to the growing share of this market. Training programs and various workshops on 3D cell culture provided by institutes are expected to drive the demand for 3D cell culture products & systems over the forecast period.
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The North American region accounted for the highest revenue share of over 43% and led the global 3D Cell Culture Market in 2021. The region will hold its leading position throughout the forecast period. The availability of private and government funding for the innovation of advanced 3D cell culture models accounts for this growth in the region. High healthcare spending and the presence of numerous universities and research organizations investigating various stem cell-based methods push the growth in the sector. In December 2020, Researchers from Mayo Clinic and Terasaki Institute in the US developed visible hydrogels that can be used for the monitoring and control of hemorrhage.
Asia Pacific is likely to grow at the fastest CAGR in the global 3D cell culture market and is likely to maintain the same trend during the forecast period. This is attainable due to growing investments by several companies and rising healthcare spending in developing economies like China and India in the region. Also, government support & planned initiatives are expected to support the growth of the 3D Cell Culture Market in near future.
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The global 3D cell culture market is fairly concentrated, with a few big and medium-sized market participants accounting for a large portion of 3D Cell Culture Market revenue. Major players are implementing numerous tactics, including mergers and acquisitions, strategic agreements and contracts, and the development and testing of 3D cell culture platforms.
Top Players' Company Profiles
The high utility of 3-dimensional models for research on respiratory disorders and Covid-19 is anticipated to provide the market with substantial potential opportunities. Organoids of the airway and air-liquid interface have been employed as experimental virology platforms to research the immune responses and infectivity of SARS-CoV-2 as well as instruments for the development and discovery of antiviral medicines. The biofabrication of realistic models that can be used for the development of novel treatments and vaccines against Covid-19 is made possible by scaffold-based and scaffold-free approaches. The introduction of new goods and widespread use of 3D methods in biological research are a couple of other significant drivers propelling market expansion. For instance, an entirely reusable microplate for 3D cell culture called the EB-Plate was introduced by the Canadian biotechnology business eNUVIO Inc. in December 2020. This is anticipated to boost the usefulness of 3-dimensional microplates, decrease the waste of single-use plastics, and advance the zero-waste movement in laboratories.
Similar to RAFT 3D cultures produced by Lonza, typical 2D analytical techniques can be used with ease. Numerous laboratories throughout the world have embraced these revolutionary technologies because they don't call for many modifications to the 2D culture methods that are now in use. In order to advance research on hepatic signalling pathways and drug-induced liver injury and to improve in vitro hepatotoxicity testing, Lonza has also created 3D cell culture models.
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According to our global 3D cell culture market analysis, By application, the cancer research segment is expected to maintain its dominance throughout the forecast period. By the end user, biotechnology and pharmaceutical industries are expected to dominate the 3D Cell Culture Market throughout the forecast period. Furthermore, North America is expected to maintain its dominance throughout the forecast period due to the presence of several pharmaceutical and biotechnology companies that use 3D culture technology in collaboration with research institutes and clinical laboratories to develop regenerative medicines and drug discovery and development. Furthermore, the region's adoption of 3D cell culture procedures is expected to be fueled by an increase in demand for organ transplantation and an increase in R&D efforts centered on technologically advanced solutions.
|Market size value in 2021||USD 1.56067 billion|
|Market size value in 2028||USD 372.186 billion|
|Forecast Unit (Value)||USD Billion|
|Regions covered||North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)|
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For the Global 3D Cell Culture Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global 3D Cell Culture Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
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The Asia Pacific region is expected to show the fastest growth in coming years. As the major investments by key market players in india and china are propelling the growth of the market in following region.
The two largest end user segments are pharmaceutical and biotechnology. They both together account for 43.8% share of the 3D cell culture market.
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