Global Tissue Engineering Market

Tissue Engineering Market Size, Share, Growth Analysis, By Material(Synthetic Material, and Biologically Derived Material), By Application(Cord blood & Cell Banking, Gynecology, Cancer, Skin & Integumentary), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35H2236 | Region: Global | Published Date: February, 2024
Pages: 219 |Tables: 66 |Figures: 75

Tissue Engineering Market Insights

Global Tissue Engineering Market size was valued at USD 13 Billion in 2021 and is poised to grow from USD 14.39 Billion in 2022 to USD 32.45 Billion by 2030, at a CAGR of 10.7% during the forecast period (2023-2030).

The primary purpose of the tissue engineering market is to address the increasing demand for organ transplantation and tissue regeneration. Traditional transplantation methods face limitations such as organ shortage, transplant rejection, and long waiting lists. Tissue engineering offers a promising solution by providing bioengineered tissues and organs that can be customized to suit individual patient needs. This technology has the potential to revolutionize the treatment of various diseases and injuries.

The rising incidence of chronic diseases, such as cardiovascular disorders, orthopedic conditions, and organ failures, is a significant driving factor for the tissue engineering market. Tissue engineering offers potential treatments and regenerative solutions for these conditions. Tissue engineering research and development involve significant investment, including expensive laboratory equipment, research materials, and clinical trials. The high costs associated with development and regulatory approval act as a restraining factor for market growth. The global tissue engineering market is driven by the growing prevalence of chronic diseases, advancements in stem cell research, and technological innovations. However, high development costs, regulatory challenges, integration/functionality issues, and manufacturing scalability remain as key restraining factors and challenges. Opportunities lie in personalized medicine and regenerative medicine therapies, which hold immense potential for improving patient care and revolutionizing healthcare practices.

Market Snapshot - 2024-2031

Global Market Size

USD 13 Billion

Largest Segment

Synthetic Material

Fastest Growth

Synthetic Material

Growth Rate

10.7% CAGR

Global Tissue Engineering Market 2022-2030 ($ Bn)
Country Share for North America Region- 2022 (%)

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Tissue Engineering Market Segmental Analysis

The global tissue engineering market is segmented on the basis of material, type, application, and region. Based on material type, the market is segmented into synthetic material, and biologically derived material. In terms of application, the market is grouped into cord blood & cell banking, gynecology, cancer, skin & integumentary, dental, cardiology & vascular, and others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Global Tissue Engineering Market Analysis by Material Type

Synthetic materials are artificially created materials that are designed to mimic the properties of natural tissues. These materials offer several advantages, such as controlled degradation, mechanical strength, and ease of manufacturing. Some commonly used synthetic materials in tissue engineering include polymers like polyethylene glycol (PEG), polycaprolactone (PCL), poly (lactic-co-glycolic acid) (PLGA), and polyethylene terephthalate (PET). Synthetic materials provide a customizable platform for tissue engineering, allowing researchers to tailor their properties to meet specific tissue requirements.

Biologically derived materials, also known as natural or biomimetic materials, are derived from biological sources. These materials closely resemble the composition and structure of native tissues, offering an environment conducive to cell attachment, growth, and regeneration. Biologically derived materials can include naturally occurring polymers such as collagen, gelatin, hyaluronic acid, chitosan, and alginate, as well as decellularized extracellular matrix (ECM) scaffolds derived from tissues or organs. These materials provide a biocompatible and bioactive substrate for cell integration and tissue development.

Global Tissue Engineering Market Analysis by Application

The tissue engineering market was predominantly led by the orthopedics, musculoskeletal, and spine segments, driven by the increasing prevalence of musculoskeletal problems. Within the orthopedic regeneration sector, treatments such as spine, bone replacements, and bone transplants played a significant role. In the United States alone, bone replacement or repair procedures accounted for approximately 900,000 surgical interventions annually, contributing to a substantial increase in healthcare costs by $59.9 billion due to nearly 15 million fracture cases each year.

The cardiology and vascular tissue engineering sector is projected to witness the highest growth rate during the analysis period, primarily due to the rising incidence of cardiovascular diseases worldwide. Key players in this sector are actively involved in developing stem cell therapies to heal, restore, and revascularize damaged cardiac tissues. Additionally, research efforts are focused on gene therapy, advanced biologics, and small molecules to promote regeneration of injured cardiac cells. The use of autologous and allogeneic stem cells, either individually or in combination, is gaining prominence to study the impact of cardiovascular diseases. Moreover, advancements in tissue engineering technology, such as the development of 3D heart muscles and Engineered Heart Tissue (EHT), hold promising potential for future market expansion.

Global Tissue Engineering Market Size By Material Type 2022(%), 2023 (%)

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Tissue Engineering Market Regional Insights

North America held the largest share in 2022, primarily driven by factors such as increased awareness of stem cell therapy and a growing geriatric population. The region also benefits from advanced diagnostic and treatment technologies for chronic diseases, ample availability of private and government funding, and high healthcare expenditures, which contribute to a larger market share.

Asia Pacific is expected to exhibit the fastest compound annual growth rate (CAGR) during the forecast period. Japan, in particular, has emerged as a leading country fostering technological advancements in tissue engineering. Additionally, the increasing prevalence of clinical disorders, including cancer, in Asia contributes to the growth of the tissue engineering market. Factors such as the evolution of 3D bioprinting technology and the rise of medical tourism in the region also drive market growth.

Global Tissue Engineering Market Size By Geography, 2022-2030, 2024-2031
  • Largest
  • Fastest

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Tissue Engineering Market Dynamics

Global Tissue Engineering Market Drivers

Increasing Prevalence of Chronic Diseases

  • The rising incidence of chronic diseases, such as cardiovascular disorders, orthopedic conditions, and organ failures, has been a key driver for the tissue engineering market. Tissue engineering provides potential solutions for tissue and organ repair or replacement, offering improved treatment options for patients with chronic conditions.

Technological Advancements

  • Continued advancements in biomaterials, bio fabrication techniques, and stem cell research have been driving the tissue engineering market. These advancements enable the development of more complex and functional tissues, improving the success rate of tissue engineering therapies and expanding their applications.

Global Tissue Engineering Market Restraints

Regulatory Challenges

  • The tissue engineering market faces regulatory challenges related to safety, efficacy, and ethical concerns associated with the use of bioengineered tissues and cells. Stringent regulations and lengthy approval processes can impede the market's progress and limit the availability of tissue engineering products and therapies.

High Development Costs

  • Tissue engineering research and development involve significant investment, including expensive laboratory equipment, research materials, and clinical trials. The high costs associated with development and regulatory approval pose a challenge for market growth, particularly for smaller companies and institutions with limited resources.

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Tissue Engineering Market Competitive Landscape

The global tissue engineering market has a competitive landscape characterized by the presence of a mix of established companies, emerging players, and research institutions. The market is driven by technological advancements, research collaborations, product innovations, and strategic partnerships. Here is an elaboration on the competitive landscape of the tissue engineering market. The competitive landscape of the tissue engineering market is dynamic, with companies constantly striving to innovate and improve their products. Key factors for success in this market include technological advancements, strong research and development capabilities, regulatory compliance, intellectual property protection, and strategic partnerships with healthcare providers and biotechnology companies.

Top Player’s Company Profiles in Global Tissue Engineering Market

  • Organogenesis Holdings Inc. (US)
  • Acelity L.P. Inc. (US)
  • Medtronic plc (Ireland)
  • Integra LifeSciences Corporation (US)
  • Stryker Corporation (US)
  • Zimmer Biomet Holdings, Inc. (US)
  • Baxter International Inc. (US)
  • Allergan plc (Ireland)
  • Smith & Nephew plc (UK)
  • Wright Medical Group N.V. (Netherlands)
  • Cook Medical Incorporated (US)
  • MiMedx Group, Inc. (US)
  • Osiris Therapeutics, Inc. (US)
  • Tissue Regenix Group plc (UK)
  • NuVasive, Inc. (US)
  • Cellular Dynamics International (US)
  • Vericel Corporation (US)
  • RepliCel Life Sciences Inc. (Canada)
  • Organovo Holdings, Inc. (US)
  • AlloSource (US)

Global Tissue Engineering Market Recent Developments

  • In September 2022, Researchers at Columbia University developed a technique to engineer functional human lungs using stem cells. The team used a combination of 3D bioprinting and tissue engineering to create a lung-like structure that could potentially be used for transplantation in the future.
  • In June 2022, Scientists at the University of Illinois developed a new bioink that can be used in 3D bioprinting to create functional human organs. The bioink is made from a combination of living cells and a hydrogel that mimics the extracellular matrix, providing a supportive environment for cell growth.
  • In April 2022, A team of researchers at Stanford University developed a 3D-printed biodegradable implant that promotes nerve regeneration. The implant provides a scaffold for nerve growth and gradually dissolves over time, allowing the nerves to regenerate naturally.
  • In November 2021, Scientists at the University of Toronto developed a bioengineered patch that can promote the regeneration of damaged heart tissue. The patch, made from a combination of cells and biomaterials, releases therapeutic proteins that stimulate the growth of new blood vessels and cardiac cells.

Tissue Engineering Key Market Trends

  • Personalized Medicine: The trend towards personalized medicine has had an impact on the tissue engineering market. Tissue engineering allows for the customization of tissues and organs to match individual patient needs, reducing the risk of rejection and improving treatment outcomes. This trend aligns with the growing demand for precision medicine and patient-centric healthcare.
  • Combination Therapies and Hybrid Approaches: Researchers are exploring the potential of combining tissue engineering approaches with other therapeutic modalities, such as gene therapy, immunotherapy, and drug delivery systems. These combination therapies aim to enhance the effectiveness and success of tissue engineering treatments and address complex medical conditions that require multiple interventions.

Tissue Engineering Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyzes the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

According to our global tissue engineering market analysis, tissue engineering aims to restore normal tissue function and improve patient outcomes. The market analysis of the tissue engineering market involves various factors, including market size, growth drivers, restraints, opportunities, and trends. Here is a detailed elaboration of the market analysis. The tissue engineering market has witnessed substantial growth in recent years and is projected to continue expanding. The market size is influenced by factors such as the prevalence of chronic diseases, advancements in regenerative medicine, and increasing investment in research and development. The rising incidence of chronic diseases, such as cardiovascular disorders, orthopedic conditions, and organ failures, is a key driver for the tissue engineering market. Tissue engineering offers potential solutions for tissue and organ repair or replacement, providing improved treatment options for patients with chronic conditions. The global tissue engineering market is witnessing significant growth driven by the rising prevalence of chronic diseases, technological advancements, and increasing demand for regenerative therapies. With ongoing research and development, the market holds immense potential for addressing unmet medical needs and revolutionizing patient care.

Report Metric Details
Market size value in 2023 USD 13 Billion
Market size value in 2031 USD 32.45 Billion
Growth Rate 10.7%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Material
    • Synthetic Material, and Biologically Derived Material
  • Application
    • Cord blood & Cell Banking, Gynecology, Cancer, Skin & Integumentary, Dental, Cardiology & Vascular, and Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Organogenesis Holdings Inc. (US)
  • Acelity L.P. Inc. (US)
  • Medtronic plc (Ireland)
  • Integra LifeSciences Corporation (US)
  • Stryker Corporation (US)
  • Zimmer Biomet Holdings, Inc. (US)
  • Baxter International Inc. (US)
  • Allergan plc (Ireland)
  • Smith & Nephew plc (UK)
  • Wright Medical Group N.V. (Netherlands)
  • Cook Medical Incorporated (US)
  • MiMedx Group, Inc. (US)
  • Osiris Therapeutics, Inc. (US)
  • Tissue Regenix Group plc (UK)
  • NuVasive, Inc. (US)
  • Cellular Dynamics International (US)
  • Vericel Corporation (US)
  • RepliCel Life Sciences Inc. (Canada)
  • Organovo Holdings, Inc. (US)
  • AlloSource (US)
Customization scope

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Tissue Engineering Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Tissue Engineering Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Tissue Engineering Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Tissue Engineering Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Tissue Engineering Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Tissue Engineering Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Tissue Engineering Market size was valued at USD 13 Billion in 2021 and is poised to grow from USD 14.39 Billion in 2022 to USD 32.45 Billion by 2030, at a CAGR of 10.7% during the forecast period (2023-2030).

The tissue engineering market has a competitive landscape characterized by the presence of a mix of established companies, emerging players, and research institutions. The market is driven by technological advancements, research collaborations, product innovations, and strategic partnerships. Here is an elaboration on the competitive landscape of the tissue engineering market. The competitive landscape of the tissue engineering market is dynamic, with companies constantly striving to innovate and improve their products. Key factors for success in this market include technological advancements, strong research and development capabilities, regulatory compliance, intellectual property protection, and strategic partnerships with healthcare providers and biotechnology companies. 'Organogenesis Holdings Inc. (US)', 'Acelity L.P. Inc. (US)', 'Medtronic plc (Ireland)', 'Integra LifeSciences Corporation (US)', 'Stryker Corporation (US)', 'Zimmer Biomet Holdings, Inc. (US)', 'Baxter International Inc. (US)', 'Allergan plc (Ireland)', 'Smith & Nephew plc (UK)', 'Wright Medical Group N.V. (Netherlands)', 'Cook Medical Incorporated (US)', 'MiMedx Group, Inc. (US)', 'Osiris Therapeutics, Inc. (US)', 'Tissue Regenix Group plc (UK)', 'NuVasive, Inc. (US)', 'Cellular Dynamics International (US)', 'Vericel Corporation (US)', 'RepliCel Life Sciences Inc. (Canada)', 'Organovo Holdings, Inc. (US)', 'AlloSource (US)'

The rising incidence of chronic diseases, such as cardiovascular disorders, orthopedic conditions, and organ failures, has been a key driver for the tissue engineering market. Tissue engineering provides potential solutions for tissue and organ repair or replacement, offering improved treatment options for patients with chronic conditions.

Personalized Medicine: The trend towards personalized medicine has had an impact on the tissue engineering market. Tissue engineering allows for the customization of tissues and organs to match individual patient needs, reducing the risk of rejection and improving treatment outcomes. This trend aligns with the growing demand for precision medicine and patient-centric healthcare.

North America held the largest share in 2022, primarily driven by factors such as increased awareness of stem cell therapy and a growing geriatric population. The region also benefits from advanced diagnostic and treatment technologies for chronic diseases, ample availability of private and government funding, and high healthcare expenditures, which contribute to a larger market share.

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