What is the global market size of 3D Cell Culture Market?

Global 3D Cell Culture Market size was valued at USD 1.12 billion in 2021 and is poised to grow from USD 1.3 billion in 2022 to USD 4.77 billion by 2030, growing at a CAGR of 15.6% in the forecast period (2023-2030).

What is the key driver of Global 3D Cell Culture Market?

The increasing prevalence of chronic diseases, such as diabetes and kidney failure, has led to a rise in demand for organ transplantation. However, there is a shortage of organs available for transplantation. 3D cell culture technology can be used to develop functional organs for transplantation, which is driving the growth of the market. For example, Organovo, a biotechnology company, has developed 3D printed liver tissues for use in drug testing and transplantation research.

What is the key market trend for Global 3D Cell Culture Market?

Growing focus on personalized medicine: There is an increasing focus on personalized medicine, which requires the development of patient-specific models for drug testing and disease modeling. 3D cell culture technology can be used to create patient-specific models that can be used for personalized drug discovery and treatment. For instance, Hubrecht Organoid Technology (HUB) has developed a platform that uses patient-derived organoids for drug testing and personalized medicine.

Which region accounted for the largest share in Global 3D Cell Culture Market?

North America held the largest market share of 45.58% in 2022. This was due to factors such as advanced healthcare infrastructure, developed economies, the presence of key players, and strategic initiatives undertaken by them. Additionally, a supportive regulatory framework, government support for the development of three-dimensional culture models, and numerous research organizations and universities investigating different stem-cell based approaches are expected to further boost the regional market. For instance, the Harvard Stem Cell Institute is utilizing stem cells to revolutionize medicine for better outcomes.

Global 3D Cell Culture Market Size, Share, Growth Analysis, By Products(Scaffold-Based, Scaffold-Free), By Application(Cancer Research, Stem Cell Research & Tissue Engineering), By End User(Biotechnology and Pharmaceutical Companies, Academic & Research Institutes) - Industry Forecast 2024-2031

Report ID: SQMIG35H2246 | Region: Global | Published Date: February, 2024
Pages: 157 | Tables: 90 | Figures: 76

Global 3D Cell Culture Market Insights

Global 3D Cell Culture Market size was valued at USD 1.3 billion in 2022 and is poised to grow from USD 1.31 billion in 2023 to USD 11.79 billion by 2031, growing at a CAGR of 18.2% during the forecast period (2024-2031).

3D system electronics have emerged as the basis for drug research, preclinical testing, tissue engineering, and basic sciences, due to their improvement over the traditional technologies. As the cells in the 3D cell culture are allowed to grow and interact in 3D dimensions, the cells can engage with the extracellular matrix which in turn improves the physiological relevance of the cells. While the conventional 2D cultures manage the cells in a flat monolayer, the 3D cultures resemble better the differentiated structures found in vivo. This diversity of 3D cell models includes 3D spheroids, organoids, bioprinted cell models, and organs-on-chips.

The spheroids develop from the cellular growth and aggregation within the 3D culture, possessing a spherical shape as well as maintaining the original cell's genetic composition. Organoids that are produced from stem cells or progenitor cells possess more mature function and a greater degree of complexity. The organs-on-chips that are microfluidic devices are the ones that are structurally like the organs cells and fluid is flowing dynamically in them.

The fast-escalating chronic diseases and medical conditions like multiple organ failures are the major factors behind the high number for organ transplantation. Nevertheless, the scarcity in donors has sparked the exploration for other ways which including regenerative medicine and tissue engineering. 3D cell culture systems are thus enhancing organoid culture and functional tissue constructs development in this way to be later used in tissue transplant and drug response analysis.

In addition, based on the development of new products that are designed to improving the tissue culture and tissue engineering, there is a market is witnessing the introduction of new products. For instance, In June 2023, 3D BioFibR launched two innovative 3D bioprinting collagen fiber products (CollaFibR 3D scaffold and μCollaFibR) in the 3D cell culture capabilities improved. Moreover, a strong demand for in-vitro testing models across various end-user segments, coupled with numerous organic and inorganic initiatives by market participants, is expected to drive market growth.

For Instance, in December 2023, Charles River Laboratories disclosed their partnership with CELLphenomics, aiming to broaden their 3D in vitro services for drug screening applications in cancer therapy.

US 3D Cell Culture Market is poised to grow at a sustainable CAGR for the next forecast year.

Global 3D Cell Culture Market Report Snapshots

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FAQs

The global 3D cell culture market is characterized by intense competition and rapid evolution driven by ongoing innovations and the growing demand for semiconductor devices. Established industry leaders vie for market dominance through product excellence, technical breakthroughs, competitive pricing, and expansive global distribution networks. Sustained investments in research and development, coupled with the adoption of groundbreaking methodologies, serve as pivotal drivers of market leadership. ' Thermo Fisher Scientific Inc. (US) ', ' Corning Incorporated (US) ', ' Merck KGaA (Germany) ', ' Lonza Group AG (Switzerland) ', ' Becton, Dickinson and Company (US) ', ' 3D Biotek LLC (US) ', ' InSphero AG (Switzerland) ', ' Synthecon Inc. (US) ', ' Tecan Trading AG (Switzerland) ', ' PromoCell GmbH (Germany) ', ' Greiner Bio-One International GmbH (Austria) ', ' Avantor, Inc. (US) ', ' Sartorius AG (Germany) ', ' Nano3D Biosciences, Inc. (US) ', ' MIMETAS B.V. (Netherlands) ', ' QGel SA (Switzerland) ', ' TissUse GmbH (Germany) ', ' SynVivo, Inc. (US) ', ' Emulate, Inc. (US) ', ' CN Bio Innovations Ltd. (UK) '

3D cell culturing techniques comprising of a novel approach are going to be a new revolution in area of regenerative medicine, which facilitate development of sophisticated tissues structures mimicking natural environment. This ground-breaking innovation enables the investigation of tissue regeneration and engineering at a deeper level which brings it to the forefront of the medical research. Along with regenerative medicine, a new trend in the medical world, these advanced cell culture technologies, like bio-3D, get also more required. Therefore, this emerging technology drives the growth of 3D cell culture industry by providing the technologies which are highly specific for researchers and clinicians for understanding and implementation of regenerative therapies.

Advanced Cell Culture Technologies: The evolution of organ-on-a-chip and microfluidic systems has surged, offering more sophisticated 3D cell culture environments. These platforms enable researchers to replicate inter-organ and tissue interactions with greater precision. For Instance, in December 2022, Emulate, Inc., introduced the Emulate Chip-A1™ Accessible Chip via an early access initiative. This latest iteration builds upon the foundation of the original Chip-S1, which replicates tissue-vascular interfaces with pertinent biomechanical stimuli like stretch and flow. The Chip-A1™ enables users to cultivate thicker tissues within the epithelial culture chamber and implement a wider array of drug treatment methods, including topical or aerosolized applications, thereby enhancing versatility and experimentation options..

In 2022, North America held the largest share of the market, representing primarily propelled by the growing concentration of universities and research institutions in the region. Additionally, growing government initiatives and funding aimed at developing advanced 3D culture models are expected to further enhance the regional business environment. For Instance, in March 2023, the ALS Society of Canada (ALS Canada) partnered with Brain Canada to invest 1.4 million in supporting nine projects focused on groundbreaking discoveries and treatments for amyotrophic lateral sclerosis (ALS).

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