Global Cell Expansion Market

Global Cell Expansion Market Size, Share, Growth Analysis, By Product(Consumables, Culture Flasks & Accessories), By Cell Type(Mammalian, Microbial) - Industry Forecast 2024-2031


Report ID: SQMIG35J2071 | Region: Global | Published Date: March, 2024
Pages: 219 | Tables: 63 | Figures: 77

Global Cell Expansion Market Insights

Global Cell Expansion Market size was valued at USD 25.21 billion in 2022 and is poised to grow from USD 27.60 billion in 2023 to USD 57.06 billion by 2031, growing at a CAGR of 9.5% during the forecast period (2024-2031). 

One of the market drivers is the growing use of automated solutions in applications involving cell expansion. Gene treatments, cell therapy products (CTP), and other biologics can be produced with less labour and money thanks to automated technologies, which also produce more dependable and dependable procedures. In the field of CTP manufacturing, the paradigm change towards Single-Use Systems (SUS) offers significant production benefits. The risks of cross-contamination and culture contamination brought on by insufficient sterilisation are eliminated by SUS. SUS provides long-term cost reductions and additionally enables the manufacture of CTP with high cell densities. As a result, an increase in SUS usage spurs the development of CTP, which accelerates market expansion. The life sciences sector is seeing a steady rise in interest in cellular therapies. Market growth is fuelled by an increase in funding from commercial and public organisations as well as by their activities to promote the development of cellular therapies. The International Society for Stem Cell Research is interested in finding stem cell-related funding opportunities for use in various scientific research applications. It is anticipated that the market will experience financial success as a result of technological development and product innovation in cell expansion fuel. However, a hindrance to the market's progress may come from a lack of advanced instrumentation and 3D cell expansion technology.

US Cell Expansion Market is poised to grow at sustainable CAGR for the next forecast year.

Market snapshot - 2024-2031

Global Market Size

USD 25.21 billion

Largest Segment

Consumables

Fastest Growth

Instruments

Growth Rate

9.5% CAGR

Global Cell Expansion Market ($ Bn)
Country Share for North America Region (%)
Global Cell Expansion Market By Product ($ Bn)
Global Cell Expansion Market By Product (%)

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Global Cell Expansion Market Segmental Analysis

Global Cell Expansion Market is segmented on the basis of product, end use, cell type and region. By product, the market is segmented into consumables, culture flasks & accessories, instruments. By end use, market is segmented into biopharmaceuticals, research institutions, cell banks, others. By cell type, the market is segmented into mammalian, microbial, others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Cell Expansion Market Analysis by End-Use

The segment for biotechnology and biopharmaceutical firms had the biggest market share in 2023 (48%), and it will continue to develop rapidly. One of the key aspects influencing the high proportion of biopharmaceutical businesses is the expanding potential of cell-based medicines in the healthcare sector. As an illustration, cellular-based therapies have skyrocketed in popularity in regenerative medicine thanks to ongoing advancements in injectable cell delivery technologies for a range of therapeutic uses. 

As a result of the numerous studies being conducted in the biomedical industry, research institutes are expected to experience the quickest CAGR between 2024 and 2031. A new technology, for instance, was developed by scientists at the University of Wisconsin in the United States to make the development of the H3N2 vaccine simple. To achieve this, scientists created a novel cell line that improved the proliferation of H3N2 for use in vaccines. This market will likely see the introduction of new items thanks to these research findings.

Cell Expansion Market Analysis by Product

With 46.8% of the market share, consumables were the most popular product category in 2023. It is predicted that it will continue to hold a strong position for the entire period of the projection. The substantial revenue share of this category is attributed to the availability of a broad range of commercial media and reagent items tailored to particular types of cells. Additionally, these items are readily available, ready to use, and come in formulas without serum.

Due to automation in bioreactors and other expansion platforms to improve the efficiency of culturing procedures, the instruments segment is anticipated to grow at the quickest CAGR throughout the projection period. The use of automated platforms streamlines the process, permits process tracking, and cuts down on the amount of time spent on manual labour, allowing for a more efficient use of staff time.

Global Cell Expansion Market By Product, 2023 (%)

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Global Cell Expansion Market Regional Insights

With a share of 43.1% in 2023, North America had the greatest proportion. Due to increased government funding initiatives that have sped up the development of regenerative medicine and cellular therapy products as well as the production of stem cells, the region will maintain its leadership position over the future years. As a result, there is a demand for cell expansion platforms in this area. For instance, the FDA and the Medical Technology Enterprise Consortium (MTEC) gave the Southwest Research Institute (SwRI) (U.S.) a total of USD 5.3 million in financing. In order to grow cells for the creation of individualized regenerative medicine, the SwRI invested these monies. The revenue generation in this area is increased by such investments.

Asia Pacific is anticipated to see the quickest growth throughout the forecast period as a result of increased efforts made by numerous local pharmaceutical and biotechnology businesses to develop and market their cellular medicines. For the purpose of commercializing its Stempeucel stem cell-based product, an Indian business by the name of Stempeutics Research Pvt. Ltd. struck an association with Kemwell Biopharma.

Global Cell Expansion Market By Region, 2024-2031
  • Largest
  • Fastest

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Global Cell Expansion Market Dynamics

Cell Expansion Market Drivers

Advancements in Genetic Engineering and Cell Line Development

  • The continuous advancements in genetic engineering technologies, such as CRISPR/Cas9, have facilitated the development of high-performing cell lines for protein expression. These technologies enable precise modification of cell genomes to enhance protein production, optimize cellular pathways, and improve product quality. The availability of well-characterized and highly productive cell lines contributes to the growth of the cell expression market.

Growing Biopharmaceutical Pipeline

  • The biopharmaceutical industry has witnessed a surge in the number of drug candidates in development, particularly in the field of targeted therapies and personalized medicine. Many of these drug candidates require efficient and reliable cell expression systems for production. The expanding biopharmaceutical pipeline drives the demand for cell expression technologies that can meet the requirements of producing diverse protein-based therapeutics.

Cell Expansion Market Restraints

Ethical Considerations in Cell Line Development

  • The development of cell lines for expression systems often involves the use of animal or human-derived cells, raising ethical concerns. Animal rights issues, ethical sourcing of human cells, and concerns related to the use of embryonic stem cells can limit the availability and adoption of certain cell lines. Ethical considerations can hinder progress and restrict the choice of cell expression systems.

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Global Cell Expansion Market Competitive Landscape

The global cell expression market is highly competitive and consists of several key players. These players engage in strategies such as collaborations, partnerships, mergers and acquisitions, and product launches to gain a competitive edge.

Cell Expansion Market Top Player’s Company Profiles

  • GE Healthcare (United States)
  • Sartorius AG (Germany)
  • Promega Corporation (United States)
  • Agilent Technologies, Inc. (United States)
  • Bio-Rad Laboratories, Inc. (United States)
  • Eppendorf AG (Germany)
  • Takara Bio Inc. (Japan)
  • GenScript Biotech Corporation (China)
  • CellGenix GmbH (Germany)
  • BD Biosciences (United States)
  • Novasep Holding S.A.S. (France)
  • OriGene Technologies, Inc. (United States)
  • Lonza Biologics Plc (United Kingdom)
  • Danaher Corporation (United States)
  • Wuxi AppTec Co., Ltd. (China)
  • Charles River Laboratories International, Inc. (United States)
  • Miltenyi Biotec GmbH (Germany)
  • New England Biolabs, Inc. (United States)
  • Qiagen N.V. (Netherlands)

Cell Expansion Market Recent Development

  • In March 2024, CellRev, in partnership with Getinge, launched a breakthrough adherent cell expansion platform, Livit ACE. Designed to eliminate many of the limitations and inefficiencies associated with adherent cell culture, Livit ACE reduces costs, enhances productivity and accelerates development times. 
  • In February 2024, Multiply Labs and Thermo Fisher Scientific expanded partnership to automate cell expansion and separation in cell therapy manufacturing. 
  • In September 2023, BioCentriq, Inc. and panCELLa, a Pluristyx Company, signed a research agreement to evaluate the ability of panCELLa's genetically engineered, induced Pluripotent Stem Cell (iPSC)-derived, feeder cells to activate and positively impact the expansion rate, total yield, and potency of manufactured NK cells. 
  • In April 2023, Abbott announced the launch of its new Freestyle Libre 3 continuous glucose monitoring (CGM) system. The Freestyle Libre 3 is a small, wearable sensor that measures blood glucose levels every minute and sends the data to a smartphone app. The system is designed to be more user-friendly and affordable than other CGM systems on the market. 
  • In March 2023, Medtronic announced the launch of its new MiniMed 780G hybrid closed-loop insulin delivery system. The MiniMed 780G system is a combination of an insulin pump and a CGM system that automatically adjusts insulin delivery based on blood glucose levels. The system is designed to help people with type 1 diabetes achieve better glycemic control. 

Global Cell Expansion Key Market Trends

Emergence of Novel Expression Systems

  • Researchers and scientists are exploring and developing novel expression systems to overcome the limitations of traditional platforms. For instance, cell-free expression systems, including cell-free protein synthesis (CFPS), are gaining attention due to their ability to produce proteins without the need for intact cells. Additionally, synthetic biology approaches are being employed to engineer cell lines with enhanced expression capabilities and more efficient protein production.

Global Cell Expansion Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.

According to our analyses, the global cell expression market is experiencing significant growth and is driven by various factors such as increasing research and development activities in the field of biotechnology, growing demand for biopharmaceuticals, advancements in cell expression technologies, and rising investments in the healthcare sector. One of the key drivers of the market is the growing demand for biopharmaceuticals. Biologics, including monoclonal antibodies, recombinant proteins, and therapeutic enzymes, are increasingly being used for the treatment of various diseases. Cell expression systems play a crucial role in the production of these biologics. As the demand for biopharmaceuticals continues to rise, there is a corresponding increase in the need for efficient and scalable cell expression technologies. The global cell expression market is experiencing significant growth and is driven by various factors such as increasing research and development activities in the field of biotechnology, growing demand for biopharmaceuticals, advancements in cell expression technologies, and rising investments in the healthcare sector.

Report Metric Details
Market size value in 2023 USD 25.21 billion
Market size value in 2031 USD 57.06 billion
Growth Rate 9.5%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Consumables, Culture Flasks & Accessories, Instruments
  • Cell Type
    • Mammalian, Microbial, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • GE Healthcare (United States)
  • Sartorius AG (Germany)
  • Promega Corporation (United States)
  • Agilent Technologies, Inc. (United States)
  • Bio-Rad Laboratories, Inc. (United States)
  • Eppendorf AG (Germany)
  • Takara Bio Inc. (Japan)
  • GenScript Biotech Corporation (China)
  • CellGenix GmbH (Germany)
  • BD Biosciences (United States)
  • Novasep Holding S.A.S. (France)
  • OriGene Technologies, Inc. (United States)
  • Lonza Biologics Plc (United Kingdom)
  • Danaher Corporation (United States)
  • Wuxi AppTec Co., Ltd. (China)
  • Charles River Laboratories International, Inc. (United States)
  • Miltenyi Biotec GmbH (Germany)
  • New England Biolabs, Inc. (United States)
  • Qiagen N.V. (Netherlands)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Global Cell Expansion Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Global Cell Expansion Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Global Cell Expansion Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Cell Expansion Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Cell Expansion Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Global Cell Expansion Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Global Cell Expansion Market size was valued at USD 25.21 billion in 2022 and is poised to grow from USD 27.60 billion in 2023 to USD 57.06 billion by 2031, growing at a CAGR of 9.5% during the forecast period (2024-2031). 

The global cell expression market is highly competitive and consists of several key players. These players engage in strategies such as collaborations, partnerships, mergers and acquisitions, and product launches to gain a competitive edge. 'Thermo Fisher Scientific Inc. (United States)', 'Merck KGaA (Germany)', 'Lonza Group Ltd. (Switzerland)', 'GE Healthcare (United States)', 'Sartorius AG (Germany)', 'Promega Corporation (United States)', 'Agilent Technologies, Inc. (United States)', 'Bio-Rad Laboratories, Inc. (United States)', 'Eppendorf AG (Germany)', 'Takara Bio Inc. (Japan)', 'GenScript Biotech Corporation (China)', 'CellGenix GmbH (Germany)', 'BD Biosciences (United States)', 'Novasep Holding S.A.S. (France)', 'OriGene Technologies, Inc. (United States)', 'Lonza Biologics Plc (United Kingdom)', 'Danaher Corporation (United States)', 'Wuxi AppTec Co., Ltd. (China)', 'Charles River Laboratories International, Inc. (United States)', 'Miltenyi Biotec GmbH (Germany)', 'New England Biolabs, Inc. (United States)', 'Qiagen N.V. (Netherlands)'

The continuous advancements in genetic engineering technologies, such as CRISPR/Cas9, have facilitated the development of high-performing cell lines for protein expression. These technologies enable precise modification of cell genomes to enhance protein production, optimize cellular pathways, and improve product quality. The availability of well-characterized and highly productive cell lines contributes to the growth of the cell expression market.

Researchers and scientists are exploring and developing novel expression systems to overcome the limitations of traditional platforms. For instance, cell-free expression systems, including cell-free protein synthesis (CFPS), are gaining attention due to their ability to produce proteins without the need for intact cells. Additionally, synthetic biology approaches are being employed to engineer cell lines with enhanced expression capabilities and more efficient protein production.

With a share of 43.1% in 2023, North America had the greatest proportion. Due to increased government funding initiatives that have sped up the development of regenerative medicine and cellular therapy products as well as the production of stem cells, the region will maintain its leadership position over the future years. As a result, there is a demand for cell expansion platforms in this area. For instance, the FDA and the Medical Technology Enterprise Consortium (MTEC) gave the Southwest Research Institute (SwRI) (U.S.) a total of USD 5.3 million in financing. In order to grow cells for the creation of individualized regenerative medicine, the SwRI invested these monies. The revenue generation in this area is increased by such investments.

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