Rational Protein Design
Global Protein Engineering Market Size, Share, Growth Analysis, By Product(Instruments, Reagents), By Technology(Rational Protein Design, Directed Evolution), By Protein Type(Insulin, Monoclonal Antibodies), By End-User(Academic Research Institutes, Contract Research Organizations) - Industry Forecast 2024-2031
Report ID:
SQMIG35H2172 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|
Tables:
124 |
Figures:
77
Global Protein Engineering Market Insights
Global Protein Engineering Market size was valued at USD 2.16 Billion in 2022 and is poised to grow from USD 2.52 Billion in 2023 to USD 8.6 Billion by 2031, at a CAGR of 16.60% during the forecast period (2024-2031).
Biotechnology and pharmaceutical companies are increasingly focusing on the research and development of protein-based therapies due to their advantages over non-protein drugs. These advantages include higher cost-effectiveness and improved patient outcomes. Moreover, there is a rising demand for targeted therapies to treat conditions such as cancer and autoimmune diseases, which is driving the adoption of protein engineering techniques. The COVID-19 pandemic has also played a significant role in boosting the industry, as protein engineering has been instrumental in the production of COVID-19 vaccines and diagnostics.
For example, in July 2021, scientists at the Eindhoven University of Technology in Germany developed a bioluminescent diagnostic kit to determine if an individual's immune system is producing antibodies in response to the coronavirus. Additionally, the industry is expected to experience substantial growth due to the increasing number of clinical trials involving protein-based treatments for COVID-19. Protein engineering is frequently used to address drug-related shortcomings and enhance the affinity and effectiveness of molecules for various purposes, including cardiovascular repair.
The growing demand for protein engineering tools for the development of cutting-edge treatments has accelerated market growth. Furthermore, the increasing number of government initiatives aimed at enhancing protein engineering capabilities is expected to offer significant growth potential. These initiatives involve increased research activities, funding allocation, and R&D spending in the field. For example, in December 2021, Nabla Bio secured $11 million in a seed fundraising round to develop an AI-first design platform for the development of next-generation antibody therapeutics.
Collaborations and partnerships between companies, such as the research partnership contract between Generate Biomedicines and Amgen in January 2022 to develop protein therapies for clinical targets, are further driving market growth. Additionally, the rising incidence of chronic and lifestyle-related disorders, including diabetes and cardiovascular conditions, is increasing the demand for protein engineering. Moreover, the growing prevalence of protein deficiency disorders like Protein-Energy Malnutrition (PEM), primarily in low-income countries, is also contributing to market growth. With increasing private and public investments in synthetic biology and ongoing advancements in personalized therapy engineering, the protein engineering industry is expected to witness substantial growth in the near future.
Market snapshot - <ul><li>Product<ul><li>Instruments, Reagents, and Software & Services</li></ul></li><li>Technology<ul><li>Rational Protein Design, Directed Evolution, Hybrid Approach, De Novo Protein Design, and Others</li></ul></li><li>Protein Type<ul><li>Insulin, Monoclonal Antibodies, Vaccines, Growth Factors, Colony Stimulating Factors, Coagulation Factors, Interferon, and Others</li></ul></li><li>End-User<ul><li>Academic Research Institutes, Contract Research Organizations, and Pharmaceutical & Biotechnology Companies</li></ul></li></ul>
Largest Segment
Fastest Growth
Rational Protein Design
Growth Rate
ProductInstruments, Reagents, and Software & ServicesTechnologyRational Protein Design, Directed Evolution, Hybrid Approach, De Novo Protein Design, and OthersProtein TypeInsulin, Monoclonal Antibodies, Vaccines, Growth Factors, Colony Stimulating Factors, Coagulation Factors, Interferon, and OthersEnd-UserAcademic Research Institutes, Contract Research Organizations, and Pharmaceutical & Biotechnology Companies CAGR
Global Protein Engineering Market 2022-2030 ($ Bn)
Country Share for North America Region- 2022 (%)
Global Protein Engineering Market Size By Technology, 2022-2030 ($ Bn)
Global Protein Engineering Market Size By Technology, 2022-2030 (%)
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Global Protein Engineering Market Segmental Analysis
The global protein engineering market is segmented based on technology, protein type, product, end user, and region. In terms of product, the market is segmented into instruments, reagents, and software & services. With respect to segmentation by technology, the market is widespread into rational protein design, directed evolution, hybrid approach, de novo protein design, and others. Based on protein type, the market is grouped into insulin, monoclonal antibodies, vaccines, growth factors, colony stimulating factors, coagulation factors, interferon, and others. By end-use, the market is segmented into academic research institutes, contract research organizations, and pharmaceutical & biotechnology companies. Regionwise, the market is widespread into North America, Europe, Asia-Pacific, South America, and MEA.
Global Protein Engineering Market Analysis by Product
The instruments segment led the global industry, accounting for 51.50% of overall revenue. One of the key reasons driving segment expansion is researchers' preference for automated technologies for encouraging quick molecular development processes. Additionally, growing demand for high-efficiency proteins engineering tools such as real-time PCR equipment and chromatography systems is expected to drive segment growth throughout the projection period.
Due to the increasing use of reagents for a number of applications, such as the synthesis of growth factors, vaccinations, monoclonal antibody production, and other medicines, the reagents segment is expected to grow at the quickest CAGR between 2023 and 2030. In addition, the use of reagents for studies and development in the creation of innovative COVID-19 vaccines has ignited chances for the introduction of novel goods in this sector, which is anticipated to grow the market in the next few years.
Global Protein Engineering Market Analysis by Technology
In 2022, rational protein design dominated the industry, accounting for more than 29.95% of total revenue. The lion's share is due to the broad application of this science in the engineering of enzymes and antibody creation. The rapid rise of commercial enzyme engineering applications has culminated in the production of enhanced and altered enzymes with the appropriate catalytic characteristics. Techniques such as site-directed mutagenesis are often utilized in rational design approaches, and their high market penetration contributes to the segment's growth.
The hybrid approach sector is expected to develop at the fastest rate over the projected period. This is due to the widespread use of hybrid techniques that combine controlled evolution and rational planning for a variety of purposes, such as the augmentation of redox protein and enzymes. These enzymes are crucial in the development of nanotechnology for bio-sensing and other significant nanotechnology engineering applications, bolstering future growth potential.
Global Protein Engineering Market Size By Technology, 2022(%), (%)
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Global Protein Engineering Market Regional Insights
North America will dominate the global industry in 2022, accounting for over 40.75% of total sales. The region is predicted to maintain its leadership over the forecast period. A growing number of collaborations promoted by leading market participants to increase their R&D skills are expected to be responsible for this region's larger share. The major goal of the partnership was to create a unique interleukin-2 (IL-2) agonist designed to specifically boost regulatory T cell (Treg) proliferation for the treatment of autoimmune diseases.
The Asia Pacific area is predicted to expand at the fastest CAGR during the projection period due to the increasing incidence of cardiovascular illnesses, cancer, and autoimmune disorders in developing Asian countries. Furthermore, because of the rapid economic growth in developing nations such as India and China, untapped potential in this region is projected to add to the sector's growth. Furthermore, the presence of an important population base for study and clinical evaluation of protein applications in engineering is predicted to boost the region's expansion.
Global Protein Engineering Market Size By Geography, 2022-2030, <ul><li>Product<ul><li>Instruments, Reagents, and Software & Services</li></ul></li><li>Technology<ul><li>Rational Protein Design, Directed Evolution, Hybrid Approach, De Novo Protein Design, and Others</li></ul></li><li>Protein Type<ul><li>Insulin, Monoclonal Antibodies, Vaccines, Growth Factors, Colony Stimulating Factors, Coagulation Factors, Interferon, and Others</li></ul></li><li>End-User<ul><li>Academic Research Institutes, Contract Research Organizations, and Pharmaceutical & Biotechnology Companies</li></ul></li></ul>
- Largest
- Fastest
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Global Protein Engineering Market Dynamics
Global Protein Engineering Market Drivers
Increasing Demand for Therapeutic Proteins
- Protein engineering plays a crucial role in the development of therapeutic proteins, such as antibodies, enzymes, and hormones. The growing prevalence of chronic diseases and the rising demand for targeted and personalized therapies are driving the need for novel and optimized therapeutic proteins.
Global Protein Engineering Market Restraints
High Cost of Research and Development
- Protein engineering requires significant investment in research and development activities, including laboratory equipment, specialized expertise, and clinical trials. The high cost associated with these activities can be a major restraint, especially for small and medium-sized companies.
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Global Protein Engineering Market Competitive Landscape
The global protein engineering market is highly competitive in nature, with several key players operating worldwide. These companies are actively involved in research and development activities, strategic partnerships, mergers and acquisitions, and product launches to strengthen their market presence. To enhance their industry footprint, prominent firms are pursuing a variety of essential tactics such as collaborations, mergers, acquisitions, and so on. For example, in 2022, Creative BioMart improved its protein engineering planning and evaluation services to aid researchers in resolving protein engineering challenges.
Top Player’s Company Profiles in Global Protein Engineering Market
- Thermo Fisher Scientific Inc.
- Merck KGaA
- Agilent Technologies, Inc.
- Genscript Biotech Corporation
- Codexis, Inc.
- Danaher Corporation
- Bio-Rad Laboratories, Inc.
- Bruker Corporation
- PerkinElmer, Inc.
- Creative Biomart
- Abcam plc
- Enzyme by Design Ltd.
- Twist Bioscience Corporation
- GenScript Biotech Corporation
- Cyrus Biotechnology, Inc.
- Integrated DNA Technologies, Inc. (IDT)
- New England Biolabs
- Genentech, Inc.
- Promega Corporation
- Sutro Biopharma, Inc.
Global Protein Engineering Market Recent Developments
- In April 2023, Scribe Therapeutics, a biotechnology company, announced a strategic partnership with Beam Therapeutics to develop next-generation CRISPR technologies for protein engineering. The collaboration aims to enhance the precision and efficiency of gene editing techniques for therapeutic applications.
- In March 2023, Arzeda, a protein design company, raised $63 million in a Series C funding round. The funding will be utilized to accelerate the development of Arzeda's protein design platform and expand its capabilities in protein engineering for industrial applications.
Global Protein Engineering Key Market Trends
- Increasing Demand for Personalized Medicine: There is a growing demand for personalized medicine, where treatments are tailored to individual patients based on their genetic makeup. Protein engineering enables the development of customized therapeutic proteins and antibodies that can target specific diseases and improve patient outcomes.
- Advancements in Computational Protein Design: Computational methods and artificial intelligence (AI) algorithms are being used to accelerate and optimize protein engineering processes. These technologies aid in protein design, prediction of protein structures, and identification of protein variants with desired properties, enhancing the efficiency and success rate of protein engineering projects.
- Rise of Antibody Engineering: Antibodies are widely used in diagnostics and therapeutics. Protein engineering techniques, such as antibody humanization, affinity maturation, and antibody fragment engineering, are being employed to enhance antibody properties, including specificity, binding affinity, and stability.
- Increasing Application in Industrial Enzymes: Protein engineering plays a vital role in the development of industrial enzymes used in various industries, including biofuels, food processing, and pharmaceuticals. Engineered enzymes offer improved catalytic activity, stability, and substrate specificity, contributing to more efficient and sustainable industrial processes.
Global Protein Engineering Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyzes the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.
According to our protein engineering market analysis, the increased focus of biotechnology and pharmaceutical businesses on the development and research of protein-based treatments due to their benefits over non-protein drugs, such as higher cost-effectiveness and better patient outcomes, can be attributed to market growth. Similarly, a growth in demand for tailored medicines for cancer and autoimmune illnesses is pushing protein engineering acceptance.
| Report Metric | Details |
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| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Global Protein Engineering Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Global Protein Engineering Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Global Protein Engineering Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Protein Engineering Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Protein Engineering Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Global Protein Engineering Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
Global Protein Engineering Market Report Snapshots
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