USD 2.10 billion
Global Sickle Cell Disease Treatment Market Size, Share, Growth Analysis, By Treatment type(Pharmaceuticals and supportive care), By End user(Hospitals, clinics) - Industry Forecast 2024-2031
Report ID:
SQMIG35D2091 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|
Tables:
62 |
Figures:
75
Global Sickle Cell Disease Treatment Market Insights
Global Sickle Cell Disease Treatment Market size was valued at USD 2.10 billion in 2022 and is poised to grow from USD 2.55 billion in 2023 to USD 12.03 billion by 2031, growing at a CAGR of 21.4% during the forecast period (2024-2031).
Global Sickle Cell Disease Treatment Market is a dynamic and vital sector focused on addressing the medical needs of individuals suffering from sickle cell disease (SCD). SCD is a genetic blood disorder characterized by abnormal hemoglobin that causes red blood cells to become rigid and crescent-shaped, leading to various complications and health issues. The purpose of the market is to develop innovative therapies, medications, and supportive care options to improve the quality of life for individuals living with SCD. The high prevalence of sickle cell disease globally, particularly in sub-Saharan Africa, the Middle East, and certain regions of Asia, highlights the urgent need for effective treatments. Additionally, advancements in medical research, including gene therapy and targeted drug development, have opened new avenues for innovative treatment approaches. Furthermore, increasing awareness about SCD and its impact on patients' lives, coupled with government initiatives and support, have fueled investments in research and development. However, the market also faces certain restraints. Limited access to healthcare resources, especially in low-income regions, poses a challenge for effective diagnosis and treatment. Additionally, the high cost associated with advanced therapies and limited reimbursement options can impede market growth. Moreover, the complex nature of the disease and the need for personalized treatment approaches contribute to the challenges faced by healthcare providers and researchers.
Key trends in the market include the emergence of precision medicine and personalized treatment options tailored to individual patients' genetic profiles. Furthermore, collaborations between pharmaceutical companies, research institutions, and advocacy groups have gained prominence in the pursuit of innovative therapies. Opportunities in the market lie in expanding access to healthcare in underserved regions, developing cost-effective treatments, and exploring novel therapeutic modalities such as gene editing and stem cell transplantation. With increasing investments in research and development, advancements in technology, and a growing focus on improving patient outcomes, the global market presents an attractive opportunity for pharmaceutical companies, biotechnology firms, and healthcare providers to make a significant impact in addressing the unmet needs of individuals living with SCD. By harnessing the power of innovation, collaboration, and patient-centric approaches, the market holds the potential to transform the lives of millions affected by this challenging disease.
US Sickle Cell Disease Treatment Market is poised to grow at a sustainable CAGR for the next forecast year.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Pharmaceuticals
Fastest Growth
Pharmaceuticals
Growth Rate
21.4% CAGR
Global Sickle Cell Disease Treatment Market ($ Bn)
Country Share for Middle East & Africa Region (%)
Global Sickle Cell Disease Treatment Market By Treatment Type ($ Bn)
Global Sickle Cell Disease Treatment Market By Treatment Type (%)
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Global Sickle Cell Disease Treatment Market Segmental Analysis
Global Sickle Cell Disease Treatment Market is segmented on the basis of treatment type, end user, and region. By treatment type, the market is segmented into pharmaceuticals and supportive care. By end user, the market is segmented into hospitals, clinics, research institutes, and others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Analysis By Treatment Type
Pharmaceuticals dominate the global sickle cell disease treatment market, which play a crucial role in managing the symptoms and complications associated with the disease. Pharmaceuticals encompass a wide range of treatment options, including disease-modifying drugs, pain management medications, and preventive therapies. These medications aim to alleviate pain, reduce inflammation, prevent complications, and improve the overall quality of life for patients with sickle cell disease. The pharmaceutical segment holds a significant market share due to the extensive research and development activities focused on developing novel drug therapies. Pharmaceutical companies are investing in the development of targeted therapies, such as hydroxyurea, which has shown remarkable efficacy in reducing painful episodes and improving survival rates. Additionally, advancements in gene therapy and gene editing technologies offer promising potential for curative treatments.
On the other hand, while supportive care is a smaller segment in terms of market size, it is anticipated to be the fastest growing segment in the sickle cell disease treatment market. Supportive care focuses on managing the complications and symptoms associated with the disease through non-pharmacological interventions and therapies. This includes blood transfusions, oxygen therapy, pain management techniques, and psychosocial support. The growing recognition of the multidimensional impact of sickle cell disease on patients' lives has driven the demand for comprehensive supportive care services. Healthcare providers are increasingly emphasizing the importance of holistic care approaches to address the physical, emotional, and social needs of individuals with sickle cell disease. This, in turn, is expected to fuel the growth of the supportive care segment.
Analysis By End User
Hospitals dominated the global sickle cell disease treatment market. Hospitals play a pivotal role in providing comprehensive care and treatment for individuals with sickle cell disease. They serve as primary healthcare centers equipped with specialized medical professionals, advanced diagnostic capabilities, and a wide range of treatment options. Hospitals offer a multidisciplinary approach, combining expertise from hematologists, genetic counselors, nurses, and other healthcare professionals to provide integrated care for SCD patients. The significance of hospitals as the largest segment is evident due to several reasons. Firstly, hospitals have the necessary infrastructure and resources to handle acute complications and emergencies associated with sickle cell diseases, such as vaso-occlusive crises, acute chest syndrome, and stroke. They provide round-the-clock medical supervision and immediate access to specialized interventions, including blood transfusions, pain management, and supportive therapies.
On the other hand, the fastest growing segment in the sickle cell disease treatment market is clinics. Clinics offer specialized outpatient care, diagnostic services, and follow-up consultations for SCD patients. They provide a more accessible and convenient healthcare setting, particularly for routine check-ups, disease monitoring, and managing less severe complications. Clinics play a crucial role in improving patient compliance and facilitating continuity of care outside of hospital settings. The growing demand for clinics stems from several factors. Firstly, the establishment of dedicated sickle cell clinics and specialized treatment centers has improved access to care, particularly in regions with a high prevalence of the disease. These clinics often employ a multidisciplinary approach, involving hematologists, nurse practitioners, and social workers, to deliver comprehensive care and patient education.
Global Sickle Cell Disease Treatment Market By Treatment Type, 2023 (%)
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Global Sickle Cell Disease Treatment Market Regional Insights
The Middle East and Africa region holds a significant market share, primarily due to the high prevalence of the condition in sub-Saharan Africa. This region faces a considerable burden of sickle cell disease, with a large number of affected individuals. As a result, there is a strong focus on improving treatment options and enhancing healthcare infrastructure to cater to the needs of patients. For example, in Nigeria, the country with the highest number of sickle cell disease cases globally, the government has launched initiatives to increase access to quality healthcare services and raise awareness about the disease. This has led to collaborations between healthcare providers, pharmaceutical companies, and research institutions to develop and deliver effective treatments.
On the other hand, North America is witnessing rapid growth in the sickle cell disease treatment market. Factors contributing to this growth include advanced healthcare infrastructure, extensive research and development activities, and favorable reimbursement policies. The region has witnessed notable advancements in precision medicine and targeted therapies for sickle cell disease. One relevant example is the approval of a breakthrough gene therapy treatment for sickle cell disease by the U.S. Food and Drug Administration (FDA). This therapy has shown promising results in clinical trials, providing hope for improved outcomes and potentially even a cure for the disease.
Global Sickle Cell Disease Treatment Market By Geography, 2024-2031
- Largest
- Fastest
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Global Sickle Cell Disease Treatment Market Dynamics
Drivers
Advancements in Gene Therapy
- Gene therapy has emerged as a promising approach in the treatment of sickle cell disease. The development of gene-editing technologies, such as CRISPR-Cas9, has opened new possibilities for correcting the underlying genetic mutation responsible for SCD. For example, in 2020, the U.S. Food and Drug Administration (FDA) approved the first gene therapy for SCD, called Zynteglo. This therapy uses a patient's own stem cells, genetically modifying them to produce healthy hemoglobin and reduce the symptoms of the disease. The advancements in gene therapy offer hope for more effective and long-lasting treatments for SCD.
Restraints
Limited Access to Healthcare Resources
- Access to quality healthcare services remains a significant challenge, particularly in low-income regions with a high prevalence of sickle cell disease. Lack of infrastructure, healthcare facilities, and trained healthcare professionals hinders effective diagnosis and treatment of SCD. Limited access to healthcare resources contributes to delayed diagnosis, inadequate management of complications, and poor patient outcomes. Addressing these resource gaps and improving healthcare infrastructure is crucial to ensure timely and appropriate care for individuals with SCD.
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Global Sickle Cell Disease Treatment Market Competitive Landscape
Global Sickle Cell Disease Treatment Market features a competitive landscape with several prominent players striving to develop effective therapies and treatments. These companies are actively engaged in research and development activities, clinical trials, and strategic collaborations to gain a competitive edge in the market. Key players in the market are investing significant resources in developing novel drugs, gene therapies, and supportive care options to address the complex challenges associated with sickle cell disease. Additionally, partnerships with academic institutions, research organizations, and patient advocacy groups are aiding in the advancement of innovative treatment approaches. With the increasing focus on precision medicine and personalized therapies, competition in the market is expected to intensify as companies strive to bring breakthrough treatments to the market and improve the lives of individuals living with sickle cell disease.
Top Player’s Company Profile
- Novartis (Switzerland)
- Pfizer (US)
- Global Blood Therapeutics (US)
- Bluebird Bio (US)
- Bristol Myers Squibb (US)
- Sangamo Therapeutics (US)
- Emmaus Life Sciences (US)
- Eli Lilly and Company (US)
- Modus Therapeutics (Sweden)
- Gamida Cell (Israel)
- Lonza Group (Switzerland)
- Addmedica (France)
- Selexys Pharmaceuticals (US)
- GlycoMimetics (US)
- Mast Therapeutics (US)
- Acceleron Pharma (US)
- Angiocrine Bioscience (US)
- Imara Inc. (US)
- AstraZeneca (UK)
- Sanofi (France)
Recent Developments
- In December 2022, Bluebird Bio Inc. made an announcement stating that the United States Food and Drug Administration (FDA) had removed a partial clinical hold on clinical studies for their gene therapy designed to treat sickle cell disease, a blood disorder. This development signifies a significant step forward in the advancement of potential treatments for sickle cell disease.
- In February 2022, Global Blood Therapeutics Inc. obtained marketing authorization for Oxbryta. This authorization allows for the use of Oxbryta as a treatment for hemolytic anemia caused by sickle cell disease (SCD) in both adult and pediatric patients aged 12 years and above. It can be used either as a standalone therapy or in combination with hydroxycarbamide. This approval represents a noteworthy milestone in improving treatment options for individuals affected by sickle cell disease.
Global Sickle Cell Disease Treatment Key Market Trends
- Personalized Medicine and Precision Therapies: There is a growing trend towards personalized medicine in the treatment of sickle cell disease. Advancements in genetic testing and understanding of individual genetic variations associated with SCD have paved the way for tailored treatment approaches. For instance, hydroxyurea, an FDA-approved medication for SCD, has demonstrated variable responses among patients. This has led to ongoing research to identify biomarkers and genetic factors that can predict treatment response, enabling the development of personalized treatment regimens for improved outcomes.
Global Sickle Cell Disease Treatment Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Treatment type team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
According to our Global Sickle Cell Disease Treatment Market analysis, the market is poised for significant growth in the coming years. The market analysis indicates that factors such as the high prevalence of sickle cell disease, increasing investments in research and development, and advancements in medical technology are driving the market's expansion. Additionally, the rising awareness about the disease and its impact, coupled with supportive government initiatives, are contributing to market growth. However, the analysis also highlights challenges such as limited access to healthcare resources, high treatment costs, and the complex nature of the disease. Nonetheless, the market presents lucrative opportunities for companies to develop innovative therapies, expand healthcare access, and collaborate with research institutions and advocacy groups to improve patient outcomes.
| Report Metric | Details |
|---|---|
| Market size value in 2023 | USD 2.10 billion |
| Market size value in 2031 | USD 12.03 billion |
| Growth Rate | 21.4% |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
|
| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Global Sickle Cell Disease Treatment Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Global Sickle Cell Disease Treatment Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Global Sickle Cell Disease Treatment Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Sickle Cell Disease Treatment Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Sickle Cell Disease Treatment Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Global Sickle Cell Disease Treatment Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
Global Sickle Cell Disease Treatment Market Report Snapshots
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