Global Pharmaceutical Intermediates Market

Pharmaceutical Intermediates Market Size, Share, Growth Analysis, By Product(Chemical intermediates, Bulk drug intermediates, and Custom intermediates), By Application(Analgesics, Anti-inflammatory drug, Cardiovascular drugs, Anti-diabetic drugs), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35I2111 | Region: Global | Published Date: February, 2024
Pages: 157 |Tables: 65 |Figures: 75

Pharmaceutical Intermediates Market Insights

Pharmaceutical Intermediates Market size was valued at USD 29 billion in 2021 and is poised to grow from USD 30.6 billion in 2022 to USD 52.6 billion by 2030, growing at a CAGR of 6.3% in the forecast period (2023-2030).

Pharmaceutical intermediates are drugs that are used as raw materials in the manufacture of bulk drugs. They are commonly used to refer to the material formed during the synthesis of the active pharmaceutical ingredient (API) prior to the processing of the API. These are usually made from high-quality basic ingredients. The intermediates are widely used in the pharmaceutical and cosmetic industries. The global market is developing due to the increasing demand in these industries. These are widely used for research and development in the pharmaceutical industry. Pharmaceutical intermediates are produced using basic materials such as coal tar or petroleum to make pesticides, drugs, resins, additives, plasticizers, and other products. However, various intermediate products can be produced during organic synthesis and used to make various drugs.

Increasing production of active pharmaceutical ingredients is driving global pharmaceutical intermediates market. The growing trend of high-tech therapies with advanced delivery systems and the development of personalized and customized medicines are increasing the demand for active pharmaceutical ingredients worldwide. The high cost associated with the acquisition of biopharmaceutical drugs is a major factor hampering the growth of global market. Also, the high capital investment required for the production of APIs is a major restraining factor that may hamper market growth. The introduction of new technologies in the pharmaceutical industry for manufacturing various drugs, as well as increased investment in research activities, is expected to provide significant growth opportunities for the market in the coming years.

US Pharmaceutical Intermediates Market is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 29 billion

Largest Segment

Bulk drug intermediates

Fastest Growth

Custom intermediates

Growth Rate

6.3% CAGR

Global pharmaceutical intermediates market, 2022-2030 ($ Bn)
Country Share for North America Region- 2022 (%)

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Pharmaceutical Intermediates Market Segmental Analysis

Global pharmaceutical intermediates market is segmented on the basis of product, application, and region. On the basis of product, global market is segmented into chemical intermediates, bulk drug intermediates and custom intermediates. On the basis of application, global market is segmented into, analgesics, anti-inflammatory drug, cardiovascular drugs, anti-diabetic drugs and anti-cancer drugs. On the basis of region, global market is divided into North America, Europe, Asia Pacific, Latin America, and MEA.

Pharmaceutical Intermediates Market Analysis by Product

On the basis of product, global pharmaceutical intermediates market is segmented into chemical intermediates, bulk drug intermediates and custom intermediates. Based on product, the bulk drug intermediates segment accounted for the largest revenue share. Bulk drug intermediates are widely used in the production of active pharmaceutical ingredients (API). API is the key ingredient used in the production of drugs that gives the targeted therapeutic effect. Also, government initiatives to promote and develop bulk drug parks are expected to drive the growth of this segment.

Custom intermediate is expected to be the fastest-growing segment during the forecast period. Custom drug intermediates are the customization of specific molecules to a specific amount to achieve a desired therapeutic effect or outcome. This segment is gradually gaining popularity in the market.

Pharmaceutical Intermediates Market Analysis by Application

On the basis of application, global pharmaceutical intermediates market is segmented into, analgesics, anti-inflammatory drug, cardiovascular drugs, anti-diabetic drugs and anti-cancer drugs. The analgesics segment accounted for around 30% of global pharmaceutical intermediates market and is expected to maintain its dominance during the forecast period.  Analgesics are frequently used to relieve pain. The increased incidence of chronic diseases such as arthritis, cancer, and cardiovascular disease is driving this segment.

The anti-cancer drugs are expected to grow at the fastest rate during the forecast period. This is due to the rising incidence of cancer among the global population. According to the International Agency for Research on Cancer, there will be around 19.3 million new cancer cases and 10 million cancer deaths worldwide in 2020. Therefore, this segment is expected to be the fastest-growing segment.

Global pharmaceutical intermediates market size, by product, 2022 (%), 2023 (%)

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Pharmaceutical Intermediates Market Regional Insights

On the basis of region, global pharmaceutical intermediates market is divided into North America, Europe, Asia Pacific, Latin America, and MEA. North America dominated the global pharmaceutical intermediates market and is expected to maintain its dominance during the forecast period. North America is dominating the market due to the presence of various pharmaceutical companies, research centres, and laboratories, and rapidly growing CMOs & CROs in the US and Canada. Also, rising investments by the government and private players to boost the growth of the market.

Asia Pacific is expected to be the most competitive market during the forecast period. Increasing investment by market players to set up manufacturing facilities in countries such as China, India, Japan, South Korea, and Singapore is fuelling the growth of the pharmaceutical intermediates market over the forecast period due to the easy and cheap availability of product ingredients and favourable government policies.

Global pharmaceutical intermediates market, by geography, 2022-2030, 2024-2031
  • Largest
  • Fastest

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Pharmaceutical Intermediates Market Dynamics

Pharmaceutical Intermediates Market Driver

  • Increasing Incidence of Chronic Diseases

The constantly increasing incidences of chronic diseases, as well as the aging population worldwide, are major factors that are expected to increase the need for drug formulations for the management of chronic diseases. According to the World Health Organization (WHO), the incidence of diabetes has increased from 108.0 million in 1980 to 422.0 million in 2014, and this number continues to rise. Also, according to the World Health Organization (WHO), the incidence of chronic diseases is expected to increase by 57% by 2020, indicating that a significant percentage of the population is suffering from chronic diseases. All these factors are driving the growth of the market during the forecast period.

  • Increasing Investments in Manufacturing

Leading pharmaceutical companies in the pharmaceutical intermediates market have announced their intentions to invest in manufacturing facilities for various reasons, including increasing pharmaceutical intermediate production capacity, reducing corporate tax rates, and expanding their global footprint and presence in emerging economies. In July 2018, Pfizer invested USD 465.0 million to build a sterile injectable plant in Portage, Michigan. This is part of its earlier announcement in 2018 of plans to invest approximately USD 5 billion in US-based capital projects as a result of the country's recent corporate tax reforms. These factors will drive the expansion of the market during the forecast period.

Pharmaceutical Intermediates Market Restraint

  • High Cost Associated With The Acquisition Of Biopharmaceutical Drugs

The high cost associated with the acquisition of biopharmaceutical drugs is a major factor hampering the growth of global pharmaceutical intermediates market. Also, the high capital investment required for the production of APIs is a major restraining factor that may hamper market growth.

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Pharmaceutical Intermediates Market Competitive Landscape

Global pharmaceutical intermediates market is highly competitive with the presence of local as well as global companies. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of global pharmaceutical intermediates market.

Pharmaceutical Intermediates Market Top Player's Company Profiles

  • BASF SE
  • Lonza Group AG
  • Thermo Fisher Scientific Inc.
  • Wuxi AppTec Co. Ltd.
  • Merck KGaA
  • Dishman Group
  • Codexis Inc.
  • Cambrex Corporation
  • Hikal Ltd.
  • Chemcon Speciality Chemicals Ltd.
  • Porton Fine Chemicals Ltd.
  • Divis Laboratories Ltd.
  • Pfizer CentreOne
  • Aurobindo Pharma Ltd.
  • Sanofi SA
  • Lianhe Chemical Technology Co. Ltd.
  • Jiangsu Hengrui Medicine Co. Ltd.
  • Shandong Xinhua Pharmaceutical Co. Ltd.
  • WuXi STA
  • Zhejiang NHU Co. Ltd.

Pharmaceutical Intermediates Market Recent Developments

  • In February 2022, the Food and Drug Administration (FDA) approved Mylan Pharmaceuticals Inc., Vitaris Inc., has given the green light for an Abbreviated New Drug Application (ANDA) for Cyclosporine Ophthalmic Emulsion 0.05%. Allergan Restasis is the first generic version to treat dry eye disease.
  • In February 2022, Cordenpharma purchased three manufacturing facilities from Vifor Pharma. These facilities will eventually be named Corden Pharma Friborg SA in Switzerland (with a branch in Ettingen) and Corden Pharma Lisbon SA in Portugal.

Pharmaceutical Intermediates Key Market Trends

  • The cost of heart disease to the nation's health care system is increasing. A key trend in the pharmaceutical intermediates market is the rise in chronic cardiovascular conditions such as heart failure and coronary artery disease. According to a paper published in July 2020 in the Curious Journal of Medical Science, ischemic heart disease (IHD) is the leading cause of death worldwide. Ischemic heart disease affects about 126 million people globally. It is expected that by 2030, there will be more than 1,845 cases of ischemic heart disease per 100,000 persons worldwide.

Pharmaceutical Intermediates Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our business information services team that collects, collates, co-relates, and analyses the data collected by means of primary exploratory research backed by the robust secondary desk research.

According to our global pharmaceutical intermediates market analysis, on the basis of product segmentation, the bulk drug intermediates segment accounted for the largest revenue share. By application segment, the analgesics segment accounted for around 30% of global market and is expected to maintain its dominance during the forecast period. North America dominated the global market and is expected to maintain its dominance during the forecast period. The rise in chronic cardiovascular conditions such as heart failure and coronary artery disease is a major trend in global market. However, the high cost associated with the acquisition of biopharmaceutical drugs is a major factor hampering the growth of global market.

Report Metric Details
Market size value in 2023 USD 29 billion
Market size value in 2031 USD 52.6 billion
Growth Rate 6.3%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Chemical intermediates, Bulk drug intermediates, and Custom intermediates
  • Application
    • Analgesics, Anti-inflammatory drug, Cardiovascular drugs, Anti-diabetic drugs, Anti-cancer drugs
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • BASF SE
  • Lonza Group AG
  • Thermo Fisher Scientific Inc.
  • Wuxi AppTec Co. Ltd.
  • Merck KGaA
  • Dishman Group
  • Codexis Inc.
  • Cambrex Corporation
  • Hikal Ltd.
  • Chemcon Speciality Chemicals Ltd.
  • Porton Fine Chemicals Ltd.
  • Divis Laboratories Ltd.
  • Pfizer CentreOne
  • Aurobindo Pharma Ltd.
  • Sanofi SA
  • Lianhe Chemical Technology Co. Ltd.
  • Jiangsu Hengrui Medicine Co. Ltd.
  • Shandong Xinhua Pharmaceutical Co. Ltd.
  • WuXi STA
  • Zhejiang NHU Co. Ltd.
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Pharmaceutical Intermediates Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Pharmaceutical Intermediates Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Pharmaceutical Intermediates Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Pharmaceutical Intermediates Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Pharmaceutical Intermediates Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Pharmaceutical Intermediates Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

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FAQs

Pharmaceutical Intermediates Market size was valued at USD 29 billion in 2021 and is poised to grow from USD 30.6 billion in 2022 to USD 52.6 billion by 2030, growing at a CAGR of 6.3% in the forecast period (2023-2030).

pharmaceutical intermediates market is highly competitive with the presence of local as well as companies. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of pharmaceutical intermediates market. 'BASF SE', 'Lonza Group AG', 'Thermo Fisher Scientific Inc.', 'Wuxi AppTec Co. Ltd.', 'Merck KGaA', 'Dishman Group', 'Codexis Inc.', 'Cambrex Corporation', 'Hikal Ltd.', 'Chemcon Speciality Chemicals Ltd.', 'Porton Fine Chemicals Ltd.', 'Divis Laboratories Ltd.', 'Pfizer CentreOne', 'Aurobindo Pharma Ltd.', 'Sanofi SA', 'Lianhe Chemical Technology Co. Ltd.', 'Jiangsu Hengrui Medicine Co. Ltd.', 'Shandong Xinhua Pharmaceutical Co. Ltd.', 'WuXi STA', 'Zhejiang NHU Co. Ltd.'

Increasing Incidence of Chronic Diseases

The cost of heart disease to the nation's health care system is increasing. A key trend in the pharmaceutical intermediates market is the rise in chronic cardiovascular conditions such as heart failure and coronary artery disease. According to a paper published in July 2020 in the Curious Journal of Medical Science, ischemic heart disease (IHD) is the leading cause of death worldwide. Ischemic heart disease affects about 126 million people globally. It is expected that by 2030, there will be more than 1,845 cases of ischemic heart disease per 100,000 persons worldwide.

On the basis of region, pharmaceutical intermediates market is divided into North America, Europe, Asia Pacific, Latin America, and MEA. North America dominated the pharmaceutical intermediates market and is expected to maintain its dominance during the forecast period. North America is dominating the market due to the presence of various pharmaceutical companies, research centres, and laboratories, and rapidly growing CMOs & CROs in the US and Canada. Also, rising investments by the government and private players to boost the growth of the market.

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