Top Orthobiologics Companies

Global Orthobiologics Market size was valued at USD 6.43 Billion in 2024 and is poised to grow from USD 6.78 Billion in 2025 to USD 10.41 Billion by 2033, growing at a CAGR of 5.5% during the forecast period (2026–2033).

The global orthobiologics market is a competitive and speedy evolving market driven by the prominent market players. The leading companies like Johnson & Johnson, Medtronic, and Stryker are holding major market share with a broader range of products like stem cells and several growth factors. There is an increasing emphasis on obedience with stringent regulatory norms that affect market entry and timelines of product development for simplified approvals. Speedy advances in technology like surgeries, strategic collaborations, and heavy investments and expenditures on R&D define the competitive landscape. 'Stryker Corporation (USA) ', 'Medtronic plc (Ireland) ', 'Zimmer Biomet Holdings, Inc. (USA) ', 'DePuy Synthes (Johnson & Johnson) (USA) ', 'Bioventus LLC (USA) ', 'Arthrex, Inc. (USA) ', 'NuVasive, Inc. (USA) ', 'Orthofix International N.V. (Netherlands) ', 'Globus Medical, Inc. (USA) ', 'Kuros Biosciences AG (Switzerland) ', 'Xtant Medical Holdings, Inc. (USA) ', 'Harvest Technologies Corporation (USA) ', 'Wright Medical Group N.V. (Netherlands) ', 'Smith & Nephew plc (UK) ', 'Bone Biologics Corp. (USA) ', 'Sano Orthopedics (USA) '

Modernized technologies and R&D are majorly impacting the growth of the orthobiologics market, innovations in PRP, stem cell therapies, and several other associated techniques are increasing the accessibility, availability, and efficacy of orthobiologics, thus impacting the market growth. Moreover, current research and trials are resulting in the emergence of novel treatment modalities and products. This improves the healing process and overall recovery. 

Growing Prominence of PRP Treatment: Platelet-Rich Plasma or PRP is gaining significant prominence for its application in joint pain, soft tissue injuries, and post-surgical recovery. Hence, it is majorly gaining popularity in regenerative applications. Moreover, the growing number of efforts and initiatives are being imposed to standardize preparation of PRP and administration policies to improve reproducibility and efficacy.  

Geographically, North America dominated the market in 2023 and is expected to lead over the forecast period owing to the presence of improved healthcare infrastructure, growing cases of musculoskeletal issues, and strong research and growing number of research and developments. North America brags about its developed healthcare infrastructure with easy access to superior technologies and well-trained professionals. Regional growth is also impacted by the rising number of sports patients that report sports injuries and osteoarthritis issues. This majorly demands improved and innovative treatments. Furthermore, increasing amount of research and development fuels modernizations in orthobiologics, resulting in the emergence of novel therapies. The key players profiled in the region include Amgen Inc., Medtronic, Zimmer Biomet, Stryker Corporation, Amedica Corporation, Bone Therapeutics, and more.