Global Orthobiologics Market

Global Orthobiologics Market Size, Share, Growth Analysis, By Product (Demineralized Bone Matrix (DBM), Allograft), By Application(Spinal Fusion, Trauma Repair), By End-Use(Hospitals, Ambulatory Surgical Centers & Orthopedic Clinics) - Industry Forecast 2022-2028


Report ID: SQMG35D2016 | Region: Global | Published Date: October, 2022 | Pages: 157

Global Orthobiologics Market Insights

Global Orthobiologics Market was valued at USD 5.01 billion in 2021, and it is expected to reach a value of USD 6.91 billion by 2028, at a CAGR of 4.7% over the forecast period (2022-2028).

The rise in the frequency of sports injuries and traffic accidents are two important factors anticipated to propel the growth of the orthobiologics market during the forecast period. It is projected that the market for orthobiologics would grow as a result of the rise in spinal diseases and disorders. It is also predicted that the growing patient desire for minimally invasive procedures will restrain the expansion of the orthobiologics market. However, the rise in the price of orthobiologics-based treatments may restrain the market's expansion throughout the forecast period. The market for orthobiologics is expanding at an accelerated rate due to the rise in the elderly and obese population.

Regenerative cellular therapies are another name for orthobiologics. Orthobiologic products contain growth factors that improve and stimulate discomfort, promote tissue healing, and aid in restoring normal function.

Market snapshot

Global Market Size

USD 5.01 billion

Largest Segment

Hospitals

Fastest Growth

Hospitals

Growth Rate

4.7% CAGR

Global Orthobiologics Market 2021-2028 ($ Bn)
Country Share for North America Region- 2021 (%)
Global Orthobiologics Market Size by End User 2021-2028 ($ Bn)
Global Orthobiologics Market Size by End User2021-2028 (%)

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Global Orthobiologics Market Segmental Analysis

The Global Orthobiologics Market is segmented based on Product, Application, End-use and Region. Based on the Product, the Global Orthobiologics Market is segmented into Demineralized Bone Matrix (DBM), Allograft, Bone Morphogenetic Protein (BMP), Viscosupplementation, Synthetic Bone Substitutes & Stem Cell Therapy. Based on the Application, the Global Orthobiologics Market is segmented into Spinal Fusion, Trauma Repair, Maxillofacial & Dental& Reconstructive Surgery. Based on End-Use, it is segmented into Hospitals, Ambulatory Surgical Centers& Orthopedic Clinics. Based on Region, it is categorized into North America, Europe, Asia-Pacific, South America, and MEA.

Analysis by Product

Viscosupplementation commanded the lion's share of the orthobiologics market in the product segment in 2015. The significant proportion is related to the widespread availability and extraordinary adoption of these medicines in conditions including osteoarthritis and hip degenerative joint degeneration. The advantages of viscosupplementation are thought to be the cause of the high adoption rate. These advantages include improved knee mobility, pain relief, reduced invasiveness, and fewer adverse effects. It is also assumed that this is due to the great demand for minimally invasive surgical treatments and the high acceptability of these techniques by the patient population.

Analysis by Application

Over 50.0% of the application segment's market share was accounted for by spinal fusion. Demineralized bone matrices, bone morphogenetic proteins, autografts, and allografts have consistently gained a dominant share in spinal fusion surgery due to their capacity to deliver high bone stability and quick bone healing while alleviating long-term spinal diseases. A bigger proportion in the application segment is thought to be the result of other advantages of orthobiological products in spinal fusion, such as quick activation of cells to commence bone growth and reduced hospital stay time and visits. The significant market shares that orthobiologics has gained is also seen to be a result of the existence of third-party insurers and the availability of reimbursement for fusion augmentation devices, which has led to growth.

Analysis by End Use

The end-use segment was dominated by hospitals. One important element contributing to the market share dominance is the growing use of orthobiological products in a variety of spinal and reconstructive procedures carried out in hospitals. In addition, it is projected that hospitals' easy access to a large variety of orthobiologics and their specialized patient care will contribute to the segment's expansion.

Additionally, frequent readmissions, significant patient turnover, and high procedure volumes all contributed to the category share. Additionally, the supportive infrastructure makes precise operating procedures possible, which is expected to significantly increase the growth potential.

Global Orthobiologics Market By End User, 2021 (%)

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Global Orthobiologics Market Regional Insights

Orthopedic Surgery in outpatient settings is increasing, favoring the North American Market. North America's market is estimated to rule the industry for the entire forecast year. The market in North America may see growth between 2019 and 2026 as a result of the business strategies of top American manufacturers, benevolent reimbursement policies, rising prevalence of degenerative bone diseases, and rising trend of orthopaedic procedures in outpatient settings. Due to the recent marketing approval for Cingal, a viscosupplement, in Europe, Europe is anticipated to be the second most lucrative region with a sizable market share..

Due to the rising demand for viscosupplements in India and the growing number of independent orthopaedic clinics, Asia Pacific is anticipated to have the highest CAGR throughout the projection period. Due to the increased need for the treatment of sports injuries and a rise in government initiatives to raise awareness of orthobiologics, Latin America and the Middle East & Africa are anticipated to have a significant market potential during the projection period.

Global Orthobiologics Market By Geography, 2021 - 2028
  • Largest
  • Fastest

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Global Orthobiologics Market Dynamics

Driver

  • Viscosupplements are in high demand to support the market.

One of the main issues affecting the elderly population is knee osteoarthritis, which is extensively treated with viscosupplements. Hyaluronic acid injections known as viscosupplements are given right into the joints. High product costs, new manufacturer entrants, and recent marketing approvals are the major variables linked to the expansion of viscosupplements segments. Additionally, the viscosupplements segments are benefiting from better reimbursement policies. Given the aforementioned aspects, it is projected that the increased demand for viscosupplements will propel the growth of the worldwide orthobiologics market during the forecast period.

  • Increase in incidences of disease and disorders

It is projected that the market for orthobiologics would grow as a result of the rise in spinal diseases and disorders. Additionally, the frequency of traffic accidents is also predicted to increase the market.

Restraint

  • Patient’s preference of treatment over invasive procedures.

It is predicted that the growing patient desire for minimally invasive procedures will restrain the expansion of the orthobiologics market. The market for orthobiologics may face additional difficulties in the near future due to the negative effects of Bmp-based therapy.

  • Surging prices for orthobiologics-based treatments.

It is also estimated that the rise in the price of orthobiologics-based treatments may restrain the market's expansion throughout the forecast period. The market is constrained by complex synthesis procedures, manufacturing regulations, and high production prices. Orthobiologics goods and treatments have high costs and insufficient reimbursements, which are additional key issues limiting this market's growth. One of the major obstacles to the expansion of the global orthobiologics market is the high cost of orthobiologics treatments and products.

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Global Orthobiologics Market Competitive Landscape

Medtronic has become the market leader because of the excellent introduction and quick uptake of infuse bone morphogenetic protein. Medtronic is anticipated to hold the largest share during the forecast period due to infuse's higher price, strong sales team, and April 2018 FDA clearance for use in a new indication for spine surgery. Musculoskeletal Transplant Foundation, Zimmer Biomet, Wright Medical Group N.V., DePuy Synthes (Johnson & Johnson Services, Inc.), Stryker, Sea Spine, Bioventus, RTI Surgical Holdings, Inc. and Anika Therapeutics, Inc. are additional companies that compete on the international market.

Top Player's Company Profiles

  • Zimmer Biomet (US)
  • Genzyme Corporation (Sanofi) (US)
  • DePuy Synthes (Johnson & Johnson Services, Inc.) (US)
  • Stryker (US)
  • Medtronic (Ireland)
  • Wright Medical Group N.V. (US)
  • Anika Therapeutics, Inc. (US)
  • SeaSpine(US)
  • Bioventus (US)
  • RTI Surgical Holdings, Inc. (Germany)
  • Musculoskeletal Transplant (US)

Recent Developments

  • In March 2022, The orthobiologics partnership between MTF Biologics and Orthofix Medical, Inc. was expanded. The arrangement includes an expansion agreement for the development of a demineralized bone matrix (DBM), which Orthofix will market under the Legacy brand name, and extends Orthofix's exclusive marketing rights to the Trinity allograft line until 2032.
  • In Feb 2021, DePuy Synthes, a division of orthopedic and neurosurgical businesses that is a part of Johnson & Johnson Medical Devices Group, has a distribution deal with Expanding Innovations Inc. of Mountain View, California for the company's X-Pac Expandable Lumbar Cage System in the United States. According to DePuy Synthes, this product enables them to provide comprehensive procedural solutions for the lumbar degenerative and minimally invasive spine segments.
  • In Feb 2021, The FITBONE intramedullary lengthening system for limb lengthening and deformity correction of the femur and tibia bones has officially launched in the United States and Europe, according to Orthofix Medical Inc., a global medical device company that offers reconstructive and regenerative orthopedic & spine solutions to physicians.

Global Orthobiologics Key Market Trends

  • The global orthobiologics market is anticipated to develop due to the high prevalence of sports-related injuries. For instance, according to a study published in November 2018 titled "Results on sports-related injuries in children from NHS emergency care dataset Oxfordshire pilot: an ecological study," 47.4 percent of emergency department visits related to sports injuries were for children between the ages of 0 and 19 and roughly 23.5 percent of admissions related to sports injuries for all ages.
  • The price of orthobiologics is fluctuating on the global orthobiologics market. A University of Alabama at Birmingham study, for instance, found that orthobiologics therapy can cost anywhere from a few hundred dollars to as much as US$ 12,000, according to an article published in Sports Health in October 2019.

Global Orthobiologics Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by the robust Secondary Desk research.

According to our Global Orthobiologics Market Analysis, the major segment of the global orthobiologics market, viscosupplements segment is projected to expand in forecasted period owing to high product costs, new manufacturer entrants, and recent marketing approvals. Furthermore, increased incidence of diseases and disorders like spinal diseases and traffic accidents will also increase the demand of the market in the forecasted area.

Report Metric Details
Market size value in 2021 USD 5.01 billion
Market size value in 2028 USD 6.91 billion
Growth Rate 4.7%
Base year 2021
Forecast period 2022-2028
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Demineralized Bone Matrix (DBM), Allograft, Bone Morphogenetic Protein (BMP), Viscosupplementation, Synthetic Bone Substitutes & Stem Cell Therapy
  • Application
    • Spinal Fusion, Trauma Repair, Maxillofacial & Dental, Reconstructive Surgery
  • End-Use
    • Hospitals, Ambulatory Surgical Centers & Orthopedic Clinics
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Zimmer Biomet (US)
  • Genzyme Corporation (Sanofi) (US)
  • DePuy Synthes (Johnson & Johnson Services, Inc.) (US)
  • Stryker (US)
  • Medtronic (Ireland)
  • Wright Medical Group N.V. (US)
  • Anika Therapeutics, Inc. (US)
  • SeaSpine(US)
  • Bioventus (US)
  • RTI Surgical Holdings, Inc. (Germany)
  • Musculoskeletal Transplant (US)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Global Orthobiologics Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Global Orthobiologics Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Global Orthobiologics Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Orthobiologics Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Orthobiologics Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Global Orthobiologics Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQ's

Global Orthobiologics Market was valued at USD 5.01 billion in 2021, and it is expected to reach a value of USD 6.91 billion by 2028, at a CAGR of 4.7% over the forecast period (2022-2028).

Medtronic has become the market leader because of the excellent introduction and quick uptake of infuse bone morphogenetic protein. Medtronic is anticipated to hold the largest share during the forecast period due to infuse's higher price, strong sales team, and April 2018 FDA clearance for use in a new indication for spine surgery. Musculoskeletal Transplant Foundation, Zimmer Biomet, Wright Medical Group N.V., DePuy Synthes (Johnson & Johnson Services, Inc.), Stryker, Sea Spine, Bioventus, RTI Surgical Holdings, Inc. and Anika Therapeutics, Inc. are additional companies that compete on the international market.'Zimmer Biomet (US)','Genzyme Corporation (Sanofi) (US)','DePuy Synthes (Johnson & Johnson Services, Inc.) (US)','Stryker (US)','Medtronic (Ireland)','Wright Medical Group N.V. (US)','Anika Therapeutics, Inc. (US)','SeaSpine(US)','Bioventus (US)','RTI Surgical Holdings, Inc. (Germany)','Musculoskeletal Transplant (US)'

Viscosupplements are in high demand to support the market.

The global orthobiologics market is anticipated to develop due to the high prevalence of sports-related injuries. For instance, according to a study published in November 2018 titled "Results on sports-related injuries in children from NHS emergency care dataset Oxfordshire pilot: an ecological study," 47.4 percent of emergency department visits related to sports injuries were for children between the ages of 0 and 19 and roughly 23.5 percent of admissions related to sports injuries for all ages.

Orthopedic Surgery in outpatient settings is increasing, favoring the North American Market. North America's market is estimated to rule the industry for the entire forecast year. The market in North America may see growth between 2019 and 2026 as a result of the business strategies of top American manufacturers, benevolent reimbursement policies, rising prevalence of degenerative bone diseases, and rising trend of orthopaedic procedures in outpatient settings. Due to the recent marketing approval for Cingal, a viscosupplement, in Europe, Europe is anticipated to be the second most lucrative region with a sizable market share..

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Global Orthobiologics Market

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