HERG Screening Market Size, Share, and Growth Analysis

Global HERG Screening Market

HERG Screening Market By Type (Gene KCNH2, Mutant KCNH2), By Ion Channel (Voltage-Gated, Ligand-Gated), By Application (Antiarrhythmic, Antiphyshotic), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35G2267 | Region: Global | Published Date: January, 2025
Pages: 187 |Tables: 91 |Figures: 76

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HERG Screening Market Insights

Global HERG Screening Market size was valued at USD 1.6 billion in 2023 and is poised to grow from USD 1.79 billion in 2024 to USD 4.37 billion by 2032, growing at a CAGR of 11.8% during the forecast period (2025-2032). 

The global hERG screening marketplace has witnessed regular increase in current years due to the increasing emphasis on drug protection and the rising demand for extra green screening strategies. The pharmaceutical and biotechnology industries are the number one drivers of this marketplace, as they always searching for dependable screening technologies to minimize the danger of drug-precipitated cardiac arrhythmias.

 Growing focus of the capacity cardiotoxicity of medicine has heightened the significance of hERG screening in the drug development technique. Continuous improvements in screening technologies, such as automatic patch clamp structures and high-throughput screening techniques, contribute to the market's growth. Stringent regulatory requirements concerning drug protection have led pharmaceutical groups to invest in hERG screening technologies to conform with recommendations.

The preliminary funding required for advanced screening gadget can be a restricting element for smaller pharmaceutical companies and research institutions. Complexity of Cardiac Safety Assessment: Despite advancements, appropriately predicting the cardiac protection profile of a drug stays tough, and there may be ongoing research to improve predictive fashions.

Market snapshot - 2025-2032

Global Market Size

USD 1.6 billion

Largest Segment

Drug Discovery

Fastest Growth

Safety Pharmacology

Growth Rate

11.8% CAGR

Global HERG Screening Market ($ Bn)
Country Share for North America Region (%)

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HERG Screening Market Segments Analysis

Global HERG Screening Market is segmented by Type, Ion Channel, Application and region. Based on Type, the market is segmented into Gene KCNH2 and Mutant KCNH2. Based on Ion Channel, the market is segmented into Voltage-Gated and Ligand-Gated. Based on Application, the market is segmented into Antiarrhythmic, Antiphyshotic, Antibiotics and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.  

Analysis by Application

Drug Discovery have generally held a sizable market percentage as hERG screening is important in the early tiers of drug discovery to identify ability compounds that could result in unfavourable cardiac results, such as arrhythmias. Ensuring the safety of drugs is a pinnacle precedence for pharmaceutical groups. Regulatory bodies, which include the FDA, mandate thorough cardiac safety assessments throughout drug improvement. HERG screening immediately aligns with these regulatory requirements, making it an imperative part of the drug discovery manner.

Safety Pharmacology includes a broader spectrum of protection exams beyond hERG screening, together with cardiovascular, critical worried system, and respiratory reviews. As drug improvement turns into more comprehensive, protection pharmacology profits significance. Safety pharmacology affords a more holistic technique to assessing the safety profile of a drug candidate. As the pharmaceutical industry emphasizes a complete expertise of capability dangers, protection pharmacology becomes an integral part of the evaluation method.

Analysis by Distribution Channel 

Automated patch clamp structures permit high-throughput screening, allowing researchers to research a massive variety of compounds efficaciously. This capability is critical inside the drug discovery method, where the screening of several compounds is a habitual requirement. Automated patch clamp systems provide high accuracy and precision in measuring ion channel pastime, consisting of hERG channels. This guarantees dependable and reproducible outcomes, important for making knowledgeable selections in drug development.

In the search for performance, high-throughput screening (HTS) technology are gaining prominence. These methods permit researchers to simultaneously examine a massive number of compounds, accelerating the drug discovery method. HTS technology facilitate the screening of a couple of compounds in parallel, allowing researchers to speedy identify capacity applicants with hERG liabilities. This parallel processing capability aligns with the enterprise's want for rapid and comprehensive tests.

Global HERG Screening Market By Application

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HERG Screening Market Regional Insights

North America, particularly the United States, houses a significant attention of pharmaceutical and biotechnology groups actively engaged in drug discovery and improvement. The robust studies infrastructure and investment contribute to the dominance of North America in the hERG screening market. The stringent regulatory environment inside the United States, governed by way of the FDA, locations a high emphasis on cardiac protection tests for the duration of drug development. This regulatory consciousness drives the demand for hERG screening technology, making North America a dominant participant within the market.

 The Asia-Pacific area, such as international locations like China and India, has witnessed a vast growth of the pharmaceutical and biotechnology industries. Increasing investments in research and development activities force the call for for superior screening technology, including hERG screening. Many pharmaceutical groups from North America and Europe outsource elements in their drug discovery and improvement techniques to international locations within the Asia-Pacific location due to cost benefits. This outsourcing fashion similarly propels the adoption of hERG screening technologies within the place.

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Global HERG Screening Market By Region
  • Largest
  • Fastest

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HERG Screening Market Dynamics

Drivers

Increasing Emphasis on Drug Safety

  • The heightened emphasis on drug protection is a number one driving force, compelling corporations to invest in advanced screening technology to discover potential compounds with unfavourable cardiac effects at an early level of drug discovery.

Increasing Emphasis on Technological Advancements

  • The technological advancements play a pivotal function, with the continuous evolution of screening methods which includes automated patch clamp systems and excessive-throughput screening. These improvements decorate efficiency, accuracy, and the overall abilities of hERG screening tactics.

Restraints

High Cost Associated with Acquiring and Maintaining Advanced Screening Equipment

  • One of the main market restraints this is the high price related to acquiring and keeping superior screening equipment, inclusive of automatic patch clamp structures. This initial monetary barrier can be especially tough for smaller pharmaceutical organizations and research institutions, proscribing their get admission to to contemporary hERG screening technology.

High Complexity of Correctly Predicting Cardiac Protection

  • The complexity of correctly predicting cardiac protection, even with superior screening techniques.  

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HERG Screening Market Competitive Landscape

The competitive environment of the HERG Screening market is dynamic and is characterised by way of the energetic participation of predominant life sciences and generation groups striving to offer present day solutions to pharmaceutical and biotechnology entities. Key players in this market engage in strategic projects such as collaborations, partnerships, and acquisitions to bolster their product portfolios and extend their marketplace presence. The opposition is driven by means of a focal point on imparting advanced technology, along with automated patch clamp structures and excessive-throughput screening techniques, which beautify the efficiency and accuracy of hERG screening processes.

Top Players in HERG Screening Market

  • Cytocentrics AG (Germany) 
  • Charles River Laboratories (US) 
  • Thermo Fisher Scientific Inc. (US) 
  • PerkinElmer Inc. (US) 
  • Eurofins Scientific SE (Luxembourg) 
  • Nanion Technologies GmbH (Germany) 
  • SB Drug Discovery (UK) 
  • B'SYS GmbH (Switzerland) 
  • RedShift BioAnalytics, Inc. (US) 
  • Icagen, Inc. (a division of Eurofins DiscoverX) (US) 
  • Apredica (a division of Eurofins DiscoverX) (US) 
  • Inotrem S.A. (France) 
  • Axxam S.p.A. (Italy) 
  • Ncardia AG (Germany)

Recent Developments

  • August 2023: Metrion Biosciences strengthens its dedication to small molecule drug development with the release of its Good Laboratory Practice (GLP) hERG screening service. This new imparting expands their competencies and ensures adherence to the very best regulatory standards.
  • November 2023: FUJIFILM India is spearheading a campaign to decorate early breast cancer detection in women's healthcare. Their "Find It Early, Fight It Early" initiative, released in Faridabad, targets to break down breast most cancers stigma. The company will extend this marketing campaign to 19 cities, working with 35 technologically superior diagnostic centres equipped with their Amulet digital mammography solution. 
  • April 2023: Evotec SE has officially inaugurated Cyprotex US, LLC, its new facility in Framingham, Massachusetts. As according to the assertion made by using Evotec in February, Cyprotex US, LLC is about to relocate to a spacious 30,000 rectangular foot facility at 2 hundred Staples Drive in Massachusetts. The modern day facility at Cyprotex boasts the brand new technology in mass spectrometry and liquid dealing with automation, resulting in vast efficiency improvements, improved potential, and faster turnaround instances.

HERG Screening  Key Market Trends

HERG Screening Market SkyQuest Analysis

SkyQuest's ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research. 

Global HERG Screening marketplace evaluation reveals a dynamic marketplace with some of standout tendencies and difficulties. The market is driven through heightened drug protection issues, technological advancements in computerized patch clamp structures, and regulatory necessities for cardiac safety assessments. However, the enterprise faces restraints because of the excessive charges related to superior screening equipment and challenges in accurately predicting cardiac protection. Product kind analysis emphasizes the dominance of automatic patch clamp systems. Regionally, North America leads because of its strong pharmaceutical research, while the Asia-Pacific location experiences rapid increase, pushed with the aid of a growing pharmaceutical industry. Key tendencies encompass the growing adoption of excessive-throughput screening and the integration of AI technologies for stronger predictive skills.

Report Metric Details
Market size value in 2023 USD 1.6 billion
Market size value in 2032 USD 4.37 billion
Growth Rate 11.8%
Base year 2024
Forecast period 2025-2032
Forecast Unit (Value) USD Billion
Segments covered
  • Type
    • Gene KCNH2, Mutant KCNH2
  • Ion Channel
    • Voltage-Gated, Ligand-Gated
  • Application
    • Antiarrhythmic, Antiphyshotic, Antibiotics, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Cytocentrics AG (Germany) 
  • Charles River Laboratories (US) 
  • Thermo Fisher Scientific Inc. (US) 
  • PerkinElmer Inc. (US) 
  • Eurofins Scientific SE (Luxembourg) 
  • Nanion Technologies GmbH (Germany) 
  • SB Drug Discovery (UK) 
  • B'SYS GmbH (Switzerland) 
  • RedShift BioAnalytics, Inc. (US) 
  • Icagen, Inc. (a division of Eurofins DiscoverX) (US) 
  • Apredica (a division of Eurofins DiscoverX) (US) 
  • Inotrem S.A. (France) 
  • Axxam S.p.A. (Italy) 
  • Ncardia AG (Germany)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on HERG Screening Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on HERG Screening Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the HERG Screening Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the HERG Screening Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the HERG Screening Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the HERG Screening Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Global HERG Screening Market size was valued at USD 1.6 billion in 2023 and is poised to grow from USD 1.79 billion in 2024 to USD 4.37 billion by 2032, growing at a CAGR of 11.8% during the forecast period (2025-2032). 

The competitive environment of the HERG Screening market is dynamic and is characterised by way of the energetic participation of predominant life sciences and generation groups striving to offer present day solutions to pharmaceutical and biotechnology entities. Key players in this market engage in strategic projects such as collaborations, partnerships, and acquisitions to bolster their product portfolios and extend their marketplace presence. The opposition is driven by means of a focal point on imparting advanced technology, along with automated patch clamp structures and excessive-throughput screening techniques, which beautify the efficiency and accuracy of hERG screening processes. 'Cytocentrics AG (Germany) ', 'Charles River Laboratories (US) ', 'Thermo Fisher Scientific Inc. (US) ', 'PerkinElmer Inc. (US) ', 'Eurofins Scientific SE (Luxembourg) ', 'Nanion Technologies GmbH (Germany) ', 'SB Drug Discovery (UK) ', 'B'SYS GmbH (Switzerland) ', 'RedShift BioAnalytics, Inc. (US) ', 'Icagen, Inc. (a division of Eurofins DiscoverX) (US) ', 'Apredica (a division of Eurofins DiscoverX) (US) ', 'Inotrem S.A. (France) ', 'Axxam S.p.A. (Italy) ', 'Ncardia AG (Germany)'

The heightened emphasis on drug protection is a number one driving force, compelling corporations to invest in advanced screening technology to discover potential compounds with unfavourable cardiac effects at an early level of drug discovery.

Rising Consumer Awareness and increased use of clean label products: The increasing adoption of Automated Patch Clamp Systems, driven through their excessive throughput abilities and unique measurements. These systems have become necessary for pharmaceutical and biotechnology businesses, permitting more green screening of compounds for ability hERG liabilities. Additionally, there is a developing emphasis on High-Throughput Screening (HTS) technology, as they allow researchers to simultaneously evaluate a large variety of compounds, expediting the screening process. 

North America, particularly the United States, houses a significant attention of pharmaceutical and biotechnology groups actively engaged in drug discovery and improvement. The robust studies infrastructure and investment contribute to the dominance of North America in the hERG screening market. The stringent regulatory environment inside the United States, governed by way of the FDA, locations a high emphasis on cardiac protection tests for the duration of drug development. This regulatory consciousness drives the demand for hERG screening technology, making North America a dominant participant within the market.

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Global HERG Screening Market
HERG Screening Market

Report ID: SQMIG35G2267

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