Global Heparin Market

Heparin Market Size, Share, Growth Analysis, By Route of Administration(Intravenous and Subcutaneous), By End Use(Outpatient and Inpatient), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35H2166 | Region: Global | Published Date: April, 2024
Pages: 219 |Tables: 59 |Figures: 76

Heparin Market Insights

Global Heparin Market size was valued at USD 7.48 billion in 2022 and is poised to grow from USD 7.68 billion in 2023 to USD 9.51 billion by 2031, at a CAGR of 2.7% during the forecast period (2024-2031).

The FDA authorised the M-Enoxaparin medication from Momenta Pharmaceuticals, Inc. in August 2022. Together with Sandoz, the generics division of Novartis AG, Momenta is creating M-Enoxaparin, a generic version of lovenox with better technology. Additionally, it is given for major orthopaedic procedures like hip and knee replacement. The heparin market has recently seen new growth potential due to recent developments in heparin research that aim to produce ultra-low molecular weight heparin for use in chemotherapy. Heparin is used to treat a number of diseases and disorders, such as deep vein thrombosis, pulmonary embolism, acute coronary syndrome, atrial fibrillation, cardiopulmonary bypass, and hemofiltration during heart surgery. This gadget can be used to provide hip and knee replacements as well as other significant orthopaedic surgeries. Due to underlying causes including cardiovascular illness, the incidence of venous thrombosis is rising, which propels the growth of the global market. The market is also growing as a result of the increased use of heparin in a variety of surgical operations, including orthopaedic and heart surgeries, as well as the increase in people having these procedures. But the market's growth is constrained by a number of unfavourable heparin side effects, including thrombocytopenia caused by heparin. Further limiting factors include the fact that heparin is made from animal sources, which poses serious safety and availability issues.

Market Snapshot - 2024-2031

Global Market Size

USD 7.48 billion

Largest Segment

Subcutaneous

Fastest Growth

Subcutaneous

Growth Rate

2.7% CAGR

Global Heparin Market 2022-2030 ($ Bn)
Country Share for North America Region- 2022 (%)

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Heparin Market Segmental Analysis

Global Heparin Market is segmented on the basis of type, route of administration, source, end use and region. By type, the market is segmented into low molecular weight, ultra low weight, unfractionated. By end use, the market is segmented into outpatient and inpatient. By route of administration, the market is segmented into intravenous and subcutaneous. By source, the market is segmented into porcine, bovine, others sources. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Global Heparin Market Analysis by Type

The most popular form of heparin will be low molecular weight (LMWH), which will grow at a CAGR of 7% during the projection period. Blood thinning is accomplished with the use of the anticoagulant LMWH (low molecular weight heparin). By carefully controlling the enzymatic depolymerization process, LMWH is made up of smaller heparin fragments that are created from unfractionated heparin (UFH). A number of benefits of low molecular weight heparin over unfractionated heparin, including longer-lasting and more predictable activity than UFH and simple self-administration at home via subcutaneous injection, which minimizes or eliminates hospital stays, are anticipated to propel the growth of this market over the forecast period. Additionally, the market for low molecular weight heparin molecules is anticipated to expand as government regulatory authorities for healthcare become increasingly focused on creating and offering these goods.

Heparin with an ultra-low molecular weight will command the second-largest market share. Heparin in the form of ultra-low molecular weight heparin (ULMWH) is a medication that thins the blood and prevents blood clots from forming. Vein thromboembolism (VTE) is becoming more common in sick patients, and LMWH is being used in a variety of ways to diagnose VTE, pregnancy problems, and atrial fibrillation.

Global Heparin Market Analysis by Source

With a market share of 90.02% in 2022, the porcine industry dominated the industry. Due to its extensive use in the manufacturing of heparin, particularly low molecular weight heparins like enoxaparin, the market is anticipated to maintain its leadership over the forecast period. Heparin has not yet become widely used, however, because Jews and Muslims forbid using anything made from pigs due to their religious beliefs.

The lack of pig heparin due to the scarcity of intestinal mucosa and unfavorable social perceptions of swine heparin are primary factors boosting the growth of this category, which is anticipated to increase by 28.7% over the forecast period. The effectiveness of bovine heparin is projected to be less than that of porcine, though to slow the segment's growth.

Global Heparin Market Size By Route Of Administration 2022(%), 2023 (%)

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Heparin Market Regional Insights

In 2022, North America dominated the market and contributed 38.97% of total revenue. The increase in cardiovascular diseases and injuries is to blame for this. In addition, rising levels of healthcare spending and rising patient awareness in this region are the other variables that contribute to the high share. According to the CDC, heart disease will be one of the leading causes of death in the United States in 2022, killing 659,000 people a year, or 1 in every 4 fatalities.

The market is anticipated to grow at the fastest rate in Asia Pacific, 3.9%, during the anticipated period. Some of the main drivers of the expansion are the growing elderly population, the large chronic disease population, and expanding economy. The region that delivers the most API and crude heparin is Asia Pacific, as well. Local businesses, like Pharma Life Sciences, benefit from this. Generic versions of pharmaceuticals whose patents have expired are being produced locally at a reasonable price.

Global Heparin Market Size By Geography, 2022-2030, 2024-2031
  • Largest
  • Fastest

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Heparin Market Dynamics

Global Heparin Market Drivers

Increased Incidence of Cardiovascular Disorders and Venous Thromboembolism

  • The need for heparin is increasing as coagulation diseases like venous thromboembolism (VTE), which includes both deep vein thrombosis and pulmonary embolism, are becoming more common. VTE, which includes pulmonary embolism and deep vein thrombosis, kills over 1.2 million individuals every year. Additionally, VTE is the biggest cause of death in Europe, outpacing AIDS, breast and prostate cancer, as well as traffic accidents taken together. Additionally, the global market is growing as a result of an increase in hypertension instances brought on by an unhealthy lifestyle. Heart attacks and strokes, which are on the rise, will open up new commercial prospects. According to the American Heart Association's (AHA) heart disease and Stroke Statistics, atrial fibrillation has an impact on Americans total 5.3 million. The market may be significantly impacted by rising patient demand for heparin.
  • Despite being more common in older persons, venous thromboembolism (VTE) can strike anyone at any age. Elderly people are more likely than young people to experience numerous ailments, such as heart failure, which can lead to thrombosis. With 85% of heart failure patients being older than 65, congestive heart failure is substantially more common in the elderly. In people over 80 compared to those under 65, the prevalence of atrial fibrillation is three times higher. Such occurrences raise the risk of pulmonary embolism, especially in the elderly. Therefore, the rise in the number of elderly people increases the need for heparin to treat illnesses and the expansion of the heparin market.

Global Heparin Market Restraints

Heparin Adverse Reactions Will Slow Market Growth

  • The main obstacles impeding market expansion are negative effects of heparin. Heparin's most frequent side effect is bleeding. Heparin can result in spontaneous bleeding from lips and gums, ovaries, uterus, intestines, stomach, and open surgical incisions. Furthermore, heparin has the potential to cause heparin-induced thrombocytopenia (HIT), which raises the risk of bleeding by inducing the immune system to develop antibodies against the body's platelets. As a result, the negative side effects of heparin may limit market expansion during the projection period.

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Heparin Market Competitive Landscape

Details about each competitor are included in the heparin market competitive landscape. Included data includes an overview of the company, financials, revenue generated, market potential, investments in R&D, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launches and application dominance. Only the companies' focus on the heparin industry is mentioned in the data points above.

Top Player’s Company Profiles in Global Heparin Market

  • Pfizer Inc. (United States)
  • Sanofi S.A. (France)
  • Leo Pharma A/S (Denmark)
  • Fresenius Kabi AG (Germany)
  • Aspen Holdings (South Africa)
  • Teva Pharmaceutical Industries Ltd. (Israel)
  • Dr. Reddy's Laboratories Ltd. (India)
  • B. Braun Melsungen AG (Germany)
  • LEO Pharma A/S (Denmark)
  • Baxter International Inc. (United States)
  • Shanghai Institute of Biological Products (China)
  • Nanjing King-friend Biochemical Pharmaceutical (China)
  • Changzhou Qianhong Bio-pharma (China)
  • Opocrin S.p.A. (Italy)
  • Nantong Pharmaceutical (China)
  • Celsus Laboratories Inc. (United States)
  • Hebei Changshan Biochemical Pharmaceutical (China)
  • Bioiberica S.A.U. (Spain)
  • Dongying Tiandong Pharmaceutical (China)
  • Shenzhen Hepalink Pharmaceutical Co., Ltd. (China)
  • Pharma Action GmbH (Germany)

Global Heparin Market Recent Developments

  • The FDA authorized CorMedix's antimicrobial medication in November 2023, the first commercial product launch for the business. The medication helps patients with renal illness by reducing bloodstream infections connected to catheter use. 
  • The FDA approved Delcath Systems, Inc.'s HEPZATO KIT in August 2023 for the treatment of adult patients with unresectable hepatic metastases and metastatic uveal melanoma. 
  • The Par Sterile Products division of Endo International started shipping bivalirudin injectable in July 2023. It comes in a handy 250 mg/50 mL single-use vial that is ready to use. Being the only liquid form of bivalirudin available in the United States, this medication stands out.

Heparin Key Market Trends

  • With the increasing use of heparin and other anticoagulant therapies, there is a growing need for effective reversal agents to counteract their anticoagulant effects in emergency situations or during surgery. Research and development efforts are underway to develop novel anticoagulant reversal agents, providing an additional growth avenue for the heparin market.

Heparin Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.

According to our analyses, the global heparin market has experienced steady growth in recent years. The market size is influenced by factors such as the aging population, lifestyle changes leading to higher incidences of cardiovascular diseases, and the need for effective anticoagulant therapies. The global heparin market is driven by the increasing prevalence of cardiovascular diseases and the need for effective anticoagulant therapies. With ongoing advancements in research and development, the market is expected to continue growing, particularly in emerging economies. The availability of alternative anticoagulant therapies and the emergence of biosimilars pose challenges to the growth of the heparin market. However, strict regulations and the presence of alternative therapies create challenges for market players.

Report Metric Details
Market size value in 2023 USD 7.48 billion
Market size value in 2031 USD 9.51 billion
Growth Rate 2.7%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Route of Administration
    • Intravenous and Subcutaneous
  • End Use
    • Outpatient and Inpatient
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Pfizer Inc. (United States)
  • Sanofi S.A. (France)
  • Leo Pharma A/S (Denmark)
  • Fresenius Kabi AG (Germany)
  • Aspen Holdings (South Africa)
  • Teva Pharmaceutical Industries Ltd. (Israel)
  • Dr. Reddy's Laboratories Ltd. (India)
  • B. Braun Melsungen AG (Germany)
  • LEO Pharma A/S (Denmark)
  • Baxter International Inc. (United States)
  • Shanghai Institute of Biological Products (China)
  • Nanjing King-friend Biochemical Pharmaceutical (China)
  • Changzhou Qianhong Bio-pharma (China)
  • Opocrin S.p.A. (Italy)
  • Nantong Pharmaceutical (China)
  • Celsus Laboratories Inc. (United States)
  • Hebei Changshan Biochemical Pharmaceutical (China)
  • Bioiberica S.A.U. (Spain)
  • Dongying Tiandong Pharmaceutical (China)
  • Shenzhen Hepalink Pharmaceutical Co., Ltd. (China)
  • Pharma Action GmbH (Germany)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Heparin Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Heparin Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Heparin Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Heparin Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Heparin Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Heparin Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Heparin Market size was valued at USD 7.48 billion in 2022 and is poised to grow from USD 7.68 billion in 2023 to USD 9.51 billion by 2031, at a CAGR of 2.7% during the forecast period (2024-2031).

Details about each competitor are included in the heparin market competitive landscape. Included data includes an overview of the company, financials, revenue generated, market potential, investments in R&D, new market initiatives, presence, production sites and facilities, production capacities, company strengths and weaknesses, product launches and application dominance. Only the companies' focus on the heparin industry is mentioned in the data points above. 'Pfizer Inc. (United States)', 'Sanofi S.A. (France)', 'Leo Pharma A/S (Denmark)', 'Fresenius Kabi AG (Germany)', 'Aspen Holdings (South Africa)', 'Teva Pharmaceutical Industries Ltd. (Israel)', 'Dr. Reddy's Laboratories Ltd. (India)', 'B. Braun Melsungen AG (Germany)', 'LEO Pharma A/S (Denmark)', 'Baxter International Inc. (United States)', 'Shanghai Institute of Biological Products (China)', 'Nanjing King-friend Biochemical Pharmaceutical (China)', 'Changzhou Qianhong Bio-pharma (China)', 'Opocrin S.p.A. (Italy)', 'Nantong Pharmaceutical (China)', 'Celsus Laboratories Inc. (United States)', 'Hebei Changshan Biochemical Pharmaceutical (China)', 'Bioiberica S.A.U. (Spain)', 'Dongying Tiandong Pharmaceutical (China)', 'Shenzhen Hepalink Pharmaceutical Co., Ltd. (China)', 'Pharma Action GmbH (Germany)'

The need for heparin is increasing as coagulation diseases like venous thromboembolism (VTE), which includes both deep vein thrombosis and pulmonary embolism, are becoming more common. VTE, which includes pulmonary embolism and deep vein thrombosis, kills over 1.2 million individuals every year. Additionally, VTE is the biggest cause of death in Europe, outpacing AIDS, breast and prostate cancer, as well as traffic accidents taken together. Additionally, the market is growing as a result of an increase in hypertension instances brought on by an unhealthy lifestyle. Heart attacks and strokes, which are on the rise, will open up new commercial prospects. According to the American Heart Association's (AHA) heart disease and Stroke Statistics, atrial fibrillation has an impact on Americans total 5.3 million. The market may be significantly impacted by rising patient demand for heparin.

With the increasing use of heparin and other anticoagulant therapies, there is a growing need for effective reversal agents to counteract their anticoagulant effects in emergency situations or during surgery. Research and development efforts are underway to develop novel anticoagulant reversal agents, providing an additional growth avenue for the heparin market.

In 2022, North America dominated the market and contributed 38.97% of total revenue. The increase in cardiovascular diseases and injuries is to blame for this. In addition, rising levels of healthcare spending and rising patient awareness in this region are the other variables that contribute to the high share. According to the CDC, heart disease will be one of the leading causes of death in the United States in 2022, killing 659,000 people a year, or 1 in every 4 fatalities.

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Global Heparin Market

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