Global Gene Editing Market

Gene Editing Market Size, Share, Growth Analysis, By Type(CRISPR/Cas9, TALENS), By Application(Diagnostics, Drug discovery and development) - Industry Forecast 2024-2031


Report ID: SQMIG35H2103 | Region: Global | Published Date: February, 2024
Pages: 157 | Tables: 65 | Figures: 75

Gene Editing Market Insights

Gene Editing Market size was valued at USD 3.8 billion in 2021 and is poised to grow from USD 4.06 billion in 022 to USD 6.87 billion by 2030, growing at a CAGR of 6.8% during the forecast period (2023-2030).

The Global Gene Editing Market has experienced significant growth and advancement in recent years, revolutionizing the field of biotechnology and genetic research. Gene editing technologies, such as CRISPR-Cas9, TALENs, and zinc finger nucleases, have emerged as powerful tools for precise modification of DNA sequences in various organisms, including humans. The market is driven by the increasing demand for personalized medicine, advancements in genetic engineering, and rising investments in research and development activities. The therapeutic applications of gene editing, including the treatment of genetic disorders, cancer immunotherapy, and infectious diseases, have gained immense attention, propelling the market growth. Additionally, the agriculture sector has witnessed a surge in the adoption of gene editing techniques to develop crops with improved yield, nutritional value, and resistance to pests and diseases. Global market is characterized by intense competition among key players, including pharmaceutical companies, biotechnology firms, and research institutions. These entities are actively engaged in strategic partnerships, mergers and acquisitions, and collaborations to enhance their research capabilities and expand their product portfolios. North America dominated the global market, driven by the presence of advanced healthcare infrastructure, a strong research base, and substantial investments in genomic research. However, Asia-Pacific is expected to witness significant growth, attributed to the increasing focus on precision medicine, rising healthcare expenditure, and supportive government initiatives in countries like China, Japan, and India. The market is also fueled by supportive government initiatives, collaborations between academic institutions and biotechnology companies, and a growing number of startups entering the gene editing space. However, ethical concerns, regulatory challenges, and potential off-target effects of gene editing technologies pose significant hurdles to market growth. Nonetheless, with ongoing advancements and increasing awareness about the potential benefits, the global market is projected to witness substantial expansion in the foreseeable future.

US Gene Editing Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2024-2031

Global Market Size

USD 3.8 billion

Largest Segment

CRISPR/Cas9

Fastest Growth

CRISPR/Cas9

Growth Rate

6.8% CAGR

Global Gene Editing Market ($ Bn)
Country Share for North America Region (%)
Global Gene Editing Market By Type ($ Bn)
Global Gene Editing Market By Type (%)

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Gene Editing Market Segmental Analysis

The Global Gene Editing Market is segmented by type, application, and region. Based on type, the market can be segmented into CRISPR/Cas9, TALENS, ZFN, restriction enzymes and others. Based on application, the market is segmented into Diagnostics, Drug discovery and development, cell line, animal and plant genetic engineering and others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Gene Editing Market Analysis by Type

Among the various types of gene editing technologies, CRISPR/Cas9 holds the dominant position in the market. CRISPR/Cas9 technology has gained widespread popularity due to its simplicity, cost-effectiveness, and high precision in targeting specific DNA sequences. It allows researchers and scientists to edit genes with greater efficiency, making it a preferred choice for a wide range of applications, including therapeutic development, genetic engineering, and disease research.

The fastest growing segment in the gene editing market is the restriction enzymes segment. Restriction enzymes, also known as molecular scissors, have been widely used in gene editing for several decades. They play a crucial role in cutting DNA at specific recognition sites, enabling the insertion, deletion, or modification of genetic material. Recent advancements in restriction enzyme technology, such as the development of novel variants with improved specificity and efficiency, have propelled their adoption in gene editing applications. The increasing demand for precise gene editing tools and the expanding research activities in molecular biology are driving the growth of the restriction enzymes segment in the gene editing market.

Gene Editing Market Analysis by Application

The dominant segment in the gene editing market based on application is drug discovery and development. Gene editing technologies have revolutionized the drug discovery process by enabling the development of more targeted and effective therapies. With gene editing, researchers can precisely manipulate genes associated with diseases, allowing for a better understanding of their mechanisms and identification of potential therapeutic targets. This application of gene editing has garnered significant attention from pharmaceutical companies and research institutions, driving the dominance of the drug discovery and development segment.

The fastest growing segment in the gene editing market based on application is plant genetic engineering. Gene editing techniques offer immense potential for enhancing crop traits such as yield, nutritional value, and resistance to pests and diseases. Plant genetic engineering through gene editing enables the development of crops with improved productivity, sustainability, and resilience to changing environmental conditions. The growing global population, increasing demand for food security, and the need for sustainable agricultural practices are fueling the adoption of gene editing technologies in plant genetic engineering. As a result, the plant genetic engineering segment is experiencing rapid growth in the gene editing market.

Global Gene Editing Market By Type, 2023 (%)

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Gene Editing Market Regional Insights

North America dominated the gene editing market. North America has a well-established healthcare infrastructure, a strong presence of key biotechnology companies, and significant investments in genetic research. The region is at the forefront of gene editing advancements, with major contributions from academic institutions, pharmaceutical companies, and research organizations. The presence of robust regulatory frameworks, favorable government initiatives, and a high level of research funding have contributed to the dominance of North America in the gene editing market.

Asia Pacific is the fastest growing segment in the gene editing market. The Asia Pacific region is witnessing significant growth due to the increasing focus on precision medicine, advancements in healthcare infrastructure, and rising investments in genomic research. Countries like China, Japan, and India are actively investing in gene editing technologies and research initiatives. Additionally, the region has a large patient population, providing opportunities for gene editing applications in therapeutic interventions. The Asia Pacific region's expanding biotechnology sector, favorable government policies, and rising healthcare expenditure contribute to its status as the fastest growing segment in the gene editing market.

Global Gene Editing Market By Geography, 2024-2031
  • Largest
  • Fastest

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Gene Editing Market Dynamics

Gene Editing Market Drivers

Increasing demand for personalized medicine

  • One key driver of the gene editing market is the increasing demand for personalized medicine. Gene editing technologies offer the potential to develop tailored therapies and treatments based on an individual's genetic makeup. This personalized approach to medicine holds the promise of improved treatment outcomes, reduced side effects, and enhanced patient well-being. The growing awareness of personalized medicine and the need for targeted therapies have been significant drivers in the adoption and advancement of gene editing technologies.

Gene Editing Market Restraints

Ethical and regulatory challenges associated with the technology

  • One key restraint of the gene editing market is the ethical and regulatory challenges associated with the technology. The manipulation of genetic material raises complex ethical considerations, particularly when it comes to germline editing and inheritable genetic changes. There are ongoing debates and discussions surrounding the moral implications and potential long-term consequences of gene editing. Additionally, regulatory frameworks governing gene editing practices vary across different jurisdictions and are continuously evolving. The need for comprehensive ethical guidelines and clear regulatory pathways poses a significant restraint to the gene editing market's growth and widespread adoption.

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Gene Editing Market Competitive Landscape

The competitive landscape of the gene editing market is characterized by intense competition and a diverse range of participants, including pharmaceutical companies, biotechnology firms, research institutions, and academic organizations. The market is driven by continuous innovation and advancements in gene editing technologies, with a focus on improving precision, efficiency, and safety. Strategic partnerships, collaborations, and mergers and acquisitions are common strategies employed by market players to enhance their research capabilities, expand product portfolios, and gain a competitive edge. Additionally, the market is influenced by factors such as intellectual property rights, regulatory compliance, and the ability to address ethical concerns.

Gene Editing Market Top Player’s Company Profiles

  • Bio-Rad (US)
  • Merck KGaA (Germany)
  • OriGene Technologies (US)
  • Precision Biosciences (US)
  • Takara Bio (Japan)
  • Addgene (US)
  • Thermo Fisher Scientific Inc. (US)
  • Editas Medicine (US)
  • Sangamo Therapeutics (US)
  • Lonza Group (Switzerland)
  • Horizon Discovery (UK)
  • Intellia Therapeutics (US)
  • Caribou Biosciences (US)
  • Synthego (US)
  • GenScript Biotech Corporation (China)
  • CRISPR/Cas9 Ltd. (UK)
  • Inscripta (US)

Gene Editing Market Recent Developments

  • In April 2022, Thermo Fisher Scientific unveiled a new Gibco CTS TrueCut Cas9 Protein, manufactured under Good Manufacturing Practice (GMP) standards. This launch was significant as it addressed the increasing need for high-quality materials and comprehensive documentation in genome editing research, particularly as researchers transition from basic research to therapeutic applications. The Gibco CTS TrueCut Cas9 Protein was specifically designed for CRISPR-Cas9 genome editing in CAR T-cell therapy research, consistently demonstrating exceptional editing efficiency across various cell lines and achieving over 90% efficiency in human primary T-cells. Thermo Fisher Scientific's introduction of this product provided researchers with a reliable and efficient tool for their genome editing endeavors in therapeutic settings.
  • In June 2021, Allele Biotechnology and Alpine BioTherapeutics Corporation entered into a partnership to jointly develop induced pluripotent stem cells (iPSCs) for the treatment of retinal diseases. This collaboration aimed to leverage their respective expertise and resources in order to advance the development of iPSC-based therapies for retinal conditions. The strategic agreement bolstered Allele Biotechnology's product portfolio and facilitated their progress in the field of regenerative medicine.

Gene Editing Key Market Trends

  • One key market trend in the gene editing market is the increasing focus on therapeutic applications and the development of gene therapies. Gene editing technologies have opened up new possibilities for targeted and precise treatments of genetic disorders, cancers, and other diseases. The market is witnessing a shift towards therapeutic research and clinical applications, with a growing number of companies and researchers exploring gene editing as a potential solution for unmet medical needs. This trend reflects the transformative potential of gene editing in the field of medicine and the pursuit of innovative therapies that can directly address underlying genetic causes of diseases.

Gene Editing Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

According to our global gene editing market analysis, the market is experiencing significant growth and innovation, driven by advancements in gene editing technologies such as CRISPR/Cas9, TALENs, and ZFN. The market is dominated by the therapeutic application segment, where gene editing holds great promise for developing personalized medicines and targeted therapies. Additionally, the market is witnessing rapid growth in plant genetic engineering, driven by the increasing demand for improved crop traits. North America currently leads the market, with a strong research base and favorable regulatory frameworks. However, the Asia Pacific region is emerging as the fastest-growing segment, fueled by investments in precision medicine and genomic research. The market is highly competitive, with companies actively engaging in collaborations and partnerships. Ethical and regulatory challenges remain as key restraints, but ongoing advancements in technology and evolving guidelines are shaping the future of the global market.

Report Metric Details
Market size value in 2023 USD 3.8 billion
Market size value in 2031 USD 6.87 billion
Growth Rate 6.8%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Type
    • CRISPR/Cas9, TALENS, ZFN, restriction enzymes and others
  • Application
    • Diagnostics, Drug discovery and development, cell line, animal and plant genetic engineering and others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Bio-Rad (US)
  • Merck KGaA (Germany)
  • OriGene Technologies (US)
  • Precision Biosciences (US)
  • Takara Bio (Japan)
  • Addgene (US)
  • Thermo Fisher Scientific Inc. (US)
  • Editas Medicine (US)
  • Sangamo Therapeutics (US)
  • Lonza Group (Switzerland)
  • Horizon Discovery (UK)
  • Intellia Therapeutics (US)
  • Caribou Biosciences (US)
  • Synthego (US)
  • GenScript Biotech Corporation (China)
  • CRISPR/Cas9 Ltd. (UK)
  • Inscripta (US)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Gene Editing Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Gene Editing Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Gene Editing Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Gene Editing Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Gene Editing Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Gene Editing Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Gene Editing Market size was valued at USD 3.8 billion in 2021 and is poised to grow from USD 4.06 billion in 022 to USD 6.87 billion by 2030, growing at a CAGR of 6.8% during the forecast period (2023-2030).

The competitive landscape of the gene editing market is characterized by intense competition and a diverse range of participants, including pharmaceutical companies, biotechnology firms, research institutions, and academic organizations. The market is driven by continuous innovation and advancements in gene editing technologies, with a focus on improving precision, efficiency, and safety. Strategic partnerships, collaborations, and mergers and acquisitions are common strategies employed by market players to enhance their research capabilities, expand product portfolios, and gain a competitive edge. Additionally, the market is influenced by factors such as intellectual property rights, regulatory compliance, and the ability to address ethical concerns. 'Allele Biotech (US)', 'GE Healthcare (US)', 'Bio-Rad (US)', 'CRISPR Therapeutics (Switzerland)', 'Merck KGaA (Germany)', 'OriGene Technologies (US)', 'Precision Biosciences (US)', 'Takara Bio (Japan)', 'Addgene (US)', 'Thermo Fisher Scientific Inc. (US)', 'Editas Medicine (US)', 'Sangamo Therapeutics (US)', 'Lonza Group (Switzerland)', 'Horizon Discovery (UK)', 'Intellia Therapeutics (US)', 'Caribou Biosciences (US)', 'Synthego (US)', 'GenScript Biotech Corporation (China)', 'CRISPR/Cas9 Ltd. (UK)', 'Inscripta (US)'

One key driver of the gene editing market is the increasing demand for personalized medicine. Gene editing technologies offer the potential to develop tailored therapies and treatments based on an individual's genetic makeup. This personalized approach to medicine holds the promise of improved treatment outcomes, reduced side effects, and enhanced patient well-being. The growing awareness of personalized medicine and the need for targeted therapies have been significant drivers in the adoption and advancement of gene editing technologies.

One key market trend in the gene editing market is the increasing focus on therapeutic applications and the development of gene therapies. Gene editing technologies have opened up new possibilities for targeted and precise treatments of genetic disorders, cancers, and other diseases. The market is witnessing a shift towards therapeutic research and clinical applications, with a growing number of companies and researchers exploring gene editing as a potential solution for unmet medical needs. This trend reflects the transformative potential of gene editing in the field of medicine and the pursuit of innovative therapies that can directly address underlying genetic causes of diseases.

North America dominated the gene editing market. North America has a well-established healthcare infrastructure, a strong presence of key biotechnology companies, and significant investments in genetic research. The region is at the forefront of gene editing advancements, with major contributions from academic institutions, pharmaceutical companies, and research organizations. The presence of robust regulatory frameworks, favorable government initiatives, and a high level of research funding have contributed to the dominance of North America in the gene editing market.

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Global Gene Editing Market

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