Global Cartilage repair market

Global Cartilage Repair Market Size, Share, Growth Analysis, By Treatment modality type(Cell-Based (Chondrocyte Transplantation, Growth Factor Technology)), By Application(Hyaline, Fibrocartilage), By Treatment type(Palliative (Viscosupplementation, Debridement & Lavage)), By Site(Knee Cartilage Repair (Arthroscopic Chondroplasty, Autologous Chondrocyte) - Industry Forecast 2024-2031


Report ID: SQMIG35D2072 | Region: Global | Published Date: April, 2024
Pages: 157 | Tables: 121 | Figures: 77

Global Cartilage Repair Market Insights

Cartilage Repair Market size was valued at USD 927.63 million in 2019 and is poised to grow from USD 1040.29 million in 2023 to USD 1570.16 million by 2031, growing at a CAGR of 12.13% in the forecast period (2024-2031).

Cartilage regeneration replaces articular cartilage, which acts as a cushion between bone terminals. When the cartilage between the bones is injured or worn down, it causes pain near the sensitive nerve ends. Because cartilage lacks a blood supply, its ability to repair itself is limited. Cartilage repair is the restoration of the cartilage (articular) surface of a joint that has been impacted by an osteochondral/chondral defect. After an accident, the injured joint usually swells, and the swelling can last for weeks or even months. Articular cartilage is a defect caused by osteoarthritis that is less important for repairs due to its vascular structure and limited mitotic capabilities. Symptoms of cartilage loss include movement restrictions, muscle stiffness, soreness, inflammation, and physical disability. The rising prevalence of diabetes and obesity worldwide is expected to drive the cartilage repair market over the forecast period. Diabetes accelerates cartilage degeneration.

US Cartilage Repair Market is poised to grow at a sustainable CAGR for the next forecast year.

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Global Cartilage Repair Market Segmental Analysis

Global cartilage repair market is segmented based on treatment modality, application, treatment type, site, and region. Based on treatment modality market is segmented as cell-based (chondrocyte transplantation, growth factor technology), non-cell-based (tissue scaffolds, cell-free composites). Based on application market is segmented as hyaline, fibrocartilage. Based on treatment type market is segmented as palliative (viscosupplementation, debridement & lavage), intrinsic repair stimulus. Based on site, market is segmented as knee cartilage repair (arthroscopic chondroplasty, autologous chondrocyte, osteochondral grafts transplantation, cell-based cartilage resurfacing, microfracture, other), other. Based on region market is segmented into North America, Asia Pacific, Europe, Latin America and Middle East Africa.

Cartilage Repair Market Analysis by Treatment Type:

The treatment is classified as palliative or intrinsic repair stimulus. Because of the widespread use of the microfracture technique during cartilage repair surgeries, the intrinsic repair stimulus segment grew to be the largest. Microfracture and drilling techniques that stimulate Mesenchymal Stem Cells (MSC) to the site of injured cartilage to form repair tissue are examples of intrinsic repair stimuli.

The palliative segment is divided into two parts: viscosupplement and debridement & lavage. In order to treat OA of the thumb, toe, or other small joints, hyaluronic acid is injected into the joint to replace or supplement synovial fluid. Because of the increase in OA-induced pain and rising demand for hyaline-like cartilage regeneration, the viscosupplement segment is expected to gain market share over the forecast period.

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Global Cartilage Repair Market Regional Insights

Based on region global cartilage repair market is segmented into North America, Asia Pacific, Europe, Latin America and Middle East Africa. The Asia Pacific region is expected to grow at a faster rate. North America accounted for the largest share of the cartilage repair and regeneration market, owing to the high prevalence of osteoarthritis, the growing prevalence of sports injuries, and increased research funding in the United States and Canada. In addition, increased physician and patient awareness of innovative treatment techniques and technologies, as well as significant government investments in Cartilage Repair/Regeneration technologies and therapies, are all contributing to the market's growth in North America. Over the projection period, the Asia Pacific region is expected to grow at a faster rate than other regions. Furthermore, the increased prevalence of osteoporosis in Australia and New Zealand is leading to an increase in cartilage injury, which is expected to accelerate vertical growth. South American, Middle Eastern, and African (MEA) markets have been gradually expanding in recent years. Because of the large population suffering from chronic joint and bone problems, these markets have untapped potential.

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Global Cartilage Repair Market Dynamics

Cartilage Repair Market Drivers

  • Osteoarthritis has become increasingly common in recent years throughout the world. According to a University of North Carolina study, approximately 1 million knee and hip replacement procedures are performed in the United States each year. The annual cost of osteoarthritis in the United States is $136.8 billion. According to the Arthritis Foundation, degenerative joint diseases such as osteoarthritis will affect more than 130 million people worldwide by 2050. Two of the most common treatments for osteoarthritis are autologous chondrocyte implantation and Scaffolds implants. As a result, as the prevalence of osteoarthritis rises, so will demand for cartilage repair and regeneration products.

Cartilage Repair Market Restraint

Although cartilage repair surgeries provide better and longer-lasting results than total knee replacement surgeries, the cost of these therapies is a major barrier to patient adoption. Knee replacement procedures typically cost around USD 16,000, while cartilage repair procedures typically cost between USD 18,000 and USD 23,000, depending on the region where the procedure is performed. Such high costs undervalue the outcomes of cartilage repair therapies, resulting in a lower preference for these procedures over knee replacement surgeries.

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Global Cartilage Repair Market Competitive Landscape

The global cartilage repair market is fragmented, with a prominent market player acquiring a sizable portion. The prominent players operating in the market are constantly adopting various growth strategies to stay afloat in the market. Product launches, innovations, mergers, and acquisitions, collaborations and partnerships, and intensive R&D are some of the growth strategies that are adopted by these key players to thrive in the competitive market. The key market players are also constantly focused on R&D to supply industries with the most efficient and cost-effective.

Top Players in the Global Cartilage Repair Market

  • DePuy Synthes (a subsidiary of Johnson & Johnson)
  • Zimmer Biomet Holdings Inc.
  • Smith & Nephew plc
  • Vericel Corporation
  • Osiris Therapeutics Inc. (acquired by Smith & Nephew in 2019)
  • Histogenics Corporation
  • Anika Therapeutics Inc.
  • Arthrex Inc.
  • B. Braun Melsungen AG
  • Stryker Corporation
  • CONMED Corporation
  • Orthocell Limited
  • RTI Surgical Holdings Inc.
  • MEDIPOST Co. Ltd.
  • CellGenix GmbH
  • Tissue Regenix Group plc
  • CollPlant Biotechnologies Ltd.
  • ISTO Technologies Inc.
  • MTF Biologics
  • CartiHeal Ltd

Cartilage Repair Market Recent Developments

Stryker partnered with Minor League Baseball in April 2021 to become the official SmartRobotics joint replacement partner. Stryker has introduced Mako SmartRobotics, the latest advancement in joint replacement technology that uses 3D CT-based planning software for hip and knee replacement. It aids surgeons in creating a 3D image of each patient's distinct anatomy.

Smith-Nephew and Huma collaborated in March 2021. A remote patient monitoring app for orthopedic surgery was created using digital technology. Due to COVID-19, surgeries in the United Kingdom are operating at 50% of normal capacity, with approximately 250,000 patients on the waiting list for orthopedic operations. To reintroduce safe surgery, the company, in collaboration with Huma, devised a method for surgeons to better prepare their patients through remote monitoring app.

Global Cartilage Repair Key Market Trends

  • The number of companies focusing on the development of cartilage regeneration products has increased significantly in recent years as a result of rising government investments in regenerative medicine for cartilage regeneration research. As a result of these factors, the number of clinical trials and the development of new cartilage regeneration technologies has increased. Major market players are investing heavily in R&D, resulting in a robust pipeline of products based on various approaches to cartilage repair.

Global Cartilage Repair Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by the robust Secondary Desk research.

According to our global cartilage repair market analysis, the market is being driven by the increasing prevalence of joint and bone disorders, as well as an aging population. Technological advancements and an increasing number of road accidents and sports-related injuries are also driving the market. The prevalence of orthopaedic injuries and osteoarthritis is expected to drive the Knee Cartilage Repair Market.

Report Metric Details
Market size value in 2023 USD 927.63 million
Market size value in 2031 USD 1570.16 million
Growth Rate 12.13%
Forecast period 2024-2031
Forecast Unit (Value) USD Million
Segments covered
  • Treatment modality type
    • Cell-Based (Chondrocyte Transplantation, Growth Factor Technology), Non-Cell-Based (Tissue Scaffolds, Cell-Free Composites)
  • Application
    • Hyaline, Fibrocartilage
  • Treatment type
    • Palliative (Viscosupplementation, Debridement & Lavage), Intrinsic Repair Stimulus
  • Site
    • Knee Cartilage Repair (Arthroscopic Chondroplasty, Autologous Chondrocyte, Osteochondral Grafts Transplantation, Cell-based Cartilage Resurfacing, Microfracture, Other), Other
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • DePuy Synthes (a subsidiary of Johnson & Johnson)
  • Zimmer Biomet Holdings Inc.
  • Smith & Nephew plc
  • Vericel Corporation
  • Osiris Therapeutics Inc. (acquired by Smith & Nephew in 2019)
  • Histogenics Corporation
  • Anika Therapeutics Inc.
  • Arthrex Inc.
  • B. Braun Melsungen AG
  • Stryker Corporation
  • CONMED Corporation
  • Orthocell Limited
  • RTI Surgical Holdings Inc.
  • MEDIPOST Co. Ltd.
  • CellGenix GmbH
  • Tissue Regenix Group plc
  • CollPlant Biotechnologies Ltd.
  • ISTO Technologies Inc.
  • MTF Biologics
  • CartiHeal Ltd
Customization scope

Free report customization with purchase. Customization includes:-

  • Segments by type, application, etc
  • Company profile
  • Market dynamics & outlook
  • Region

Historical Year 2019

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Global Cartilage Repair Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Global Cartilage Repair Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Global Cartilage Repair Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Cartilage Repair Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Cartilage Repair Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Global Cartilage Repair Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Cartilage Repair Market size was valued at USD 927.63 million in 2019 and is poised to grow from USD 1040.29 million in 2023 to USD 1570.16 million by 2031, growing at a CAGR of 12.13% in the forecast period (2024-2031).

The global cartilage repair market is fragmented, with a prominent market player acquiring a sizable portion. The prominent players operating in the market are constantly adopting various growth strategies to stay afloat in the market. Product launches, innovations, mergers, and acquisitions, collaborations and partnerships, and intensive R&D are some of the growth strategies that are adopted by these key players to thrive in the competitive market. The key market players are also constantly focused on R&D to supply industries with the most efficient and cost-effective. 'DePuy Synthes (a subsidiary of Johnson & Johnson)', 'Zimmer Biomet Holdings Inc.', 'Smith & Nephew plc', 'Vericel Corporation', 'Osiris Therapeutics Inc. (acquired by Smith & Nephew in 2019)', 'Histogenics Corporation', 'Anika Therapeutics Inc.', 'Arthrex Inc.', 'B. Braun Melsungen AG', 'Stryker Corporation', 'CONMED Corporation', 'Orthocell Limited', 'RTI Surgical Holdings Inc.', 'MEDIPOST Co. Ltd.', 'CellGenix GmbH', 'Tissue Regenix Group plc', 'CollPlant Biotechnologies Ltd.', 'ISTO Technologies Inc.', 'MTF Biologics', 'CartiHeal Ltd'

Osteoarthritis has become increasingly common in recent years throughout the world. According to a University of North Carolina study, approximately 1 million knee and hip replacement procedures are performed in the United States each year. The annual cost of osteoarthritis in the United States is $136.8 billion. According to the Arthritis Foundation, degenerative joint diseases such as osteoarthritis will affect more than 130 million people worldwide by 2050. Two of the most common treatments for osteoarthritis are autologous chondrocyte implantation and Scaffolds implants. As a result, as the prevalence of osteoarthritis rises, so will demand for cartilage repair and regeneration products.

The number of companies focusing on the development of cartilage regeneration products has increased significantly in recent years as a result of rising government investments in regenerative medicine for cartilage regeneration research. As a result of these factors, the number of clinical trials and the development of new cartilage regeneration technologies has increased. Major market players are investing heavily in R&D, resulting in a robust pipeline of products based on various approaches to cartilage repair.

Based on region global cartilage repair market is segmented into North America, Asia Pacific, Europe, Latin America and Middle East Africa. The Asia Pacific region is expected to grow at a faster rate. North America accounted for the largest share of the cartilage repair and regeneration market, owing to the high prevalence of osteoarthritis, the growing prevalence of sports injuries, and increased research funding in the United States and Canada. In addition, increased physician and patient awareness of innovative treatment techniques and technologies, as well as significant government investments in Cartilage Repair/Regeneration technologies and therapies, are all contributing to the market's growth in North America. Over the projection period, the Asia Pacific region is expected to grow at a faster rate than other regions. Furthermore, the increased prevalence of osteoporosis in Australia and New Zealand is leading to an increase in cartilage injury, which is expected to accelerate vertical growth. South American, Middle Eastern, and African (MEA) markets have been gradually expanding in recent years. Because of the large population suffering from chronic joint and bone problems, these markets have untapped potential.

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