Global Viscosupplementation Market
Viscosupplementation Market

Report ID: SQMIG35B2276

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Viscosupplementation Market Size, Share, and Growth Analysis

Global Viscosupplementation Market

Viscosupplementation Market By Product (Introduction, Single Injection), By Application (Introduction, Knee Osteoarthritis), By Source (Introduction, Animal Source), By End User (Introduction, Hospitals), By Region - Industry Forecast 2026-2033


Report ID: SQMIG35B2276 | Region: Global | Published Date: January, 2026
Pages: 183 |Tables: 95 |Figures: 71

Format - word format excel data power point presentation

Viscosupplementation Market Insights

Global Viscosupplementation Market size was valued at USD 5.38 Billion in 2024 and is poised to grow from USD 5.68 Billion in 2025 to USD 8.71 Billion by 2033, growing at a CAGR of 5.5% during the forecast period (2026–2033). 

The market is experiencing steady growth fuelled by an increased prevalence of osteoarthritis (OA) predominantly in the growing elderly population. Given the rate of increase in demand for non-invasive treatment, viscosupplementation is evolving into the more favored therapy that can delay joint-removal surgery. The technological improvement in hyaluronic acid-based products and the growing knowledge and preference for minimally invasive procedures is further stimulating uptake. The growing commitment to physical mobility, the constantly increasing aging population and worldwide base of increasing sports-related injuries are all significantly driving growth in the market.

Despite these available approaches, market development is limited by several factors, such as the high cost of treatment, reimbursement issues, and the inconsistency of the efficacy of viscosupplementation between varying groups of patients. There are several other treatment alternatives including corticosteroid injections, physical therapy, and oral pain medications, which can further complicate these issues of market development. Further, there are regulatory changes, and different reimbursement policies on regional bases that can strongly inhibit viscosupplementation market penetration.

How are Emerging Technologies like AI and IOT Transforming the Viscosupplementation Market?

The combined use of AI and IoT technologies is generating enormous momentum in the viscosupplementation market and significantly altering how we treat and manage patients with osteoarthritis. AI-powered imaging products are providing superior analysis of MRI and X‑ray scans to quantify their assessment of cartilage degradation and enable clinicians to customize intra-articular hyaluronic acid injections based on each joint profile and the patient's severity-of-disease. Precision injection systems offering both robotic and image-guidance provide timely information and accuracy to minimize complications that may occur during the procedure, while improving patient confidence in the safety of these minimally invasive procedures.

In July 2025, The Shanghai Jiao Tong University and colleagues presented an AI-enabled piezoelectric wearable device that can monitor joint torque. This lightweight, portable, and low‑cost system employs boron nitride nanotubes as sensors and uses a lightweight, on-device neural network to allow for real-time monitoring. By providing real-time continuum in movement data, the device will facilitate the measurement of joint health, a very important tool for evaluating knee joint health in patients with osteoarthritis receiving viscosupplementation, rehabilitation and follow-up protocols.

Market snapshot - 2026-2033

Global Market Size

USD 4.58 Billion

Largest Segment

Osteoarthritis

Fastest Growth

Other Orthopedic Conditions

Growth Rate

4.76% CAGR

Global Viscosupplementation Market 2026-2033 ($ Bn)
Country Share by North America 2025 (%)

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Viscosupplementation Market Segments Analysis

Global Viscosupplementation Market is segmented by Product, Application, Source, End User and region. Based on Product, the market is segmented into Introduction, Single Injection, Three Injection and Five Injection. Based on Application, the market is segmented into Introduction, Knee Osteoarthritis, Hip Osteoarthritis, Shoulder Osteoarthritis and Other Applications. Based on Source, the market is segmented into Introduction, Animal Source and Non-Animal Source. Based on End User, the market is segmented into Introduction, Hospitals, Orthopedic Clinics/Ambulatory Surgical Centers (ASCS), Retail Pharmacies and Online Pharmacies. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.  

Which Application Segment Dominates the Viscosupplementation Market?

Based on the global viscosupplementation market forecast, Osteoarthritis dominates the application segment due to high prevalence globally. Osteoarthritis can be defined as a degenerative joint disease, which strongly affects a person's mobility and quality of life, leading to a demand for non-surgical and minimal invasive procedures. In addition, increasing awareness of viscosupplementation treatments, growth of clinical research, and favorable reimbursement policies in developed markets have propelled adoption of viscosupplementation for osteoarthritis.

Sports injuries is the fastest growing application segment due to the increasing frequency of joint injury among sports athletes and recreational athletes. Increased usage in sports medicine combined with innovations in combination therapies will improve the growth potential for this segment. Furthermore, the growing use of advanced diagnostic imaging and personalized treatment pathways will fuel the sector’s meteoric rise in the marketplace.

Why is Platelet-Rich Plasma the Fastest Growing Product Type Segment?

Hyaluronic acid dominates the product type segment due to its demonstrated efficacy, safety, and historical acceptance by clinicians. Hyaluronic acid is a component of synovial fluid and the ability of hyaluronic acid to reconstitute lubricating joint fluid and provide cushioning means it is being aggressively adopted in hospital and out-patient settings alike. Also, the recent proliferation of cross-linked and long-acting formulations expands both clinical use of hyaluronic acid and enhances global patient compliance.

Platelet-rich plasma (PRP) is the fastest growing product type due to increased interest in regenerative medicine and its mechanism of action by stimulating joint healing through autologous growth factors. The natural source, low rate of adverse events, expanding acceptance by orthopedic professionals is driving rapid demand. New clinical trials and regulatory advancements will continue to expand the market opportunities.

Global Viscosupplementation Market By Application 2026-2033 (%)

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Viscosupplementation Market Regional Insights

Which Drivers have Positioned North America as the Dominant Region in the Viscosupplementation Market?

As per the global viscosupplementation market analysis, North America dominates the global viscosupplementation market because of its sophisticated healthcare structures, the prevalence of osteoarthritis in the region and the span of reimbursement. There is also an increasing prevalence of awareness for viscosupplementation therapy as treatment options and improvements in the single-injection product formulations continue to develop. Additionally, government support for viscosupplementation, as well as strong clinical trial networks, add to overall market market strength in the U.S. and Canada.

US Viscosupplementation Market

The U.S has been the leader for viscosupplementation for knee osteoarthritis. The U.S. achieved this status with momentum from high procedure volumes, favorable regulatory environment, and established orthopedic clinical environment. Additionally, their recent release of single-dose HA injectables for more patient-friendly VISCO injections also improved patient compliance with appropriate treatment and reduced clinic visits. Furthermore, aging consumers and the increase in joint injuries in sports further heightens demand across both inpatient hospital and outpatient settings.

Canada Viscosupplementation Market

Canada is experiencing rapid growth due to rising diagnoses rates of arthritis and better access to treatment. Canadians are embracing extended-release viscosupplements, such as viscosupplements containing longer-acting hyaluronic acid. Continued clinical integration within physiotherapy and orthopedic clinics has demonstrated successful results. National awareness campaigns and other digital education platforms on joint care, and the promotion of all possible arthritis therapy options, has varied levels of uptake on a province-by-province basis in Canada.

How has Europe become the Fastest-Growing Viscosupplementation Market?

Europe is the fastest growing region because of aging populations and structured healthcare systems. Germany, France & the U.K. are incorporating viscosupplementation around structured care pathways for arthritis. There has also been significant growth due to cross-border collaborations in research and expanded insurance coverage from local health organizations. Further, the emphasis on early intervention for joint disorders and continuous clinical evaluations of long-acting formulations are driving the rapid growth of the viscosupplementation market across Europe.

Germany Viscosupplementation Market

Germany has a large market for viscosupplementation in Europe, with a solid orthopedic network and easily accessible insurance to see specified providers following an osteoarthritis diagnosis. With its highly organized healthcare system, there has been successful adoption of both multi-injection and single-injection HA. Existing HA products were introduced as extended-release intra-articular injections and were available to patients in the outpatient hospitals' clinics. These novels reproductive extended-release patients and can improve the patient’s adherence to prescribed treatment.

France Viscosupplementation Market

France is quickly becoming the fastest-growing country in Europe’s viscosupplementation market. The country has adopted new guidelines promoting hyaluronic acid injections as a first-line treatment for early-stage osteoarthritis. The adoption of regionally authorized cross-linked HA products in public hospitals has increased treatment rates. Reform in French healthcare to shift to outpatient care, combined with easier digital access to specialized orthopedic consultations, is increasing patient access and procedure volumes.

UK Viscosupplementation Market

The UK is rapidly growing in Europe in this market due to private clinics in urban centers adopting a single injection of hyaluronic acid (HA) and cross‑linked versions. Even though public coverage generally remains limited, increasing self-pay access as well as trials at leading research institutes and technology evidence is increasing the visibility of these treatments. Initiatives to integrate outpatient single-dose therapies in major hospital networks are increasing in the region.

How does Development across Asia Pacific Influence the Viscosupplementation Market?

Asia Pacific presents a significant growth opportunity from rapidly aging populations, growing instances of joint disease, and increasing availability of healthcare. The market is benefitting from increased government interest in non-surgical options, and a growing shift away from invasive surgical treatments. They’re improving accessibility of viscosupplementation therapies through local manufacturing and growing awareness, as well as the increase of training programs for orthopedic practitioners in countries such as Japan and South Korea.

Japan Viscosupplementation Market

Japan is the leader in the viscosupplementation market in the Asia Pacific region, with a sophisticated healthcare system and optimal geriatric care services. Japan has adopted single- and triple-injection regimens for osteoarthritis, specifically for elderly patients. With advancements in HA-based formulations with longer-lasting effects, Japan has increased usage in orthopedic hospitals. Japan's efforts to preserve mobility and quality of life for seniors will continue to move treatment options forward.

South Korea Viscosupplementation Market

South Korea is by far the fastest growing market in the Asia Pacific region driven by its rapid urbanization and healthcare digitization. Orthopedic clinics are using three-injection viscosupplementation protocols with increasing frequency especially for active aging populations. Their combination therapies (HA and PRP) used in joint clinics, have increased the standard of care. The South Korean government’s support of innovative healthcare programs and the increasing tendency toward outpatient procedures is driving faster market growth.

Global Viscosupplementation Market By Geography, 2026-2033
  • Largest
  • Fastest

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Viscosupplementation Market Dynamics

Viscosupplementation Market Drivers

Rising Osteoarthritis Prevalence Among Aging Population

  • The increasing prevalence of osteoarthritis, specifically for the older population, is one of the main factors driving the viscosupplementation market. With age comes the added risk of joint degeneration, thus non-surgical solutions for pain relief like hyaluronic acid injections are rapidly becoming in demand. This preference for minimally invasive non-surgical types of pain-relieving therapies over total joint replacements, also allows for market growth both in developed and developing countries alike.

Preference for Minimally Invasive and Outpatient Treatments

  • Patients are increasingly finding less invasive therapeutic alternatives to avoid the risks and downtime required by surgery. Viscosupplementation serves as an easy and cost-effective way to manage joint pain in the outpatient setting. Given the transition away from surgery, along with new developments in technology allowing for single injection therapy, there has been a surge in demand at orthopedic clinics and ambulatory care units.

Viscosupplementation Market Restraints

High Treatment Costs and Limited Reimbursement

  • Viscosupplementation procedures, especially those with advanced or branded hyaluronic acid formulations, are expensive. In many areas, limited or inconsistent reimbursement policies will also prevent patients from opting for this procedure. The burden to both the healthcare systems and patients individually, for out-of-pocket expenses, remains a large barrier to wider acceptance especially in price sensitive markets.

Variability in Clinical Effectiveness

  • Viscosupplementation effects differ by patient, with some reporting only short-term or poorly controlled relief of symptoms. The lack of consistent long-term efficacy data across patients and patient populations has caused some skepticism among both physicians and patients, which has affected some certainty in treatment, subsequent injections, and overall market expansion.

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Viscosupplementation Market Competitive Landscape

The global viscosupplementation market outlook is highly competitive, with market competitors like DePuy Synthes, Fidia Farmaceutici and Sanofi disrupt the market with differentiated formulations of hyaluronic acid (HA), ranging from single, to cross-linked and high-molecular-weight approaches with a goal of maximizing pain relief and minimizing frequency of injections. DePuy's MONOVISC and ORTHOVISC products are being positioned with education programs in orthopedic clinics. Fidia Farmaceutici has been creating preference for Hymovis, a two-injection product that is being developed for shoulder and ankle applications, with EMA approvals.

As per the global viscosupplementation industry analysis, the startup scene is rapidly evolving, emerging players are focused on advanced formulations and minimally invasive delivery systems. Many of the startups are utilizing biotechnology, particularly looking to develop the next generation of hyaluronic acid-based products, and are attempting to enhance efficacy and improve patient compliance. Some of them are investing in AI-driven in-app diagnostics to make personalized treatment plans. They are benefiting from the increasing incidence of osteoarthritis as well as a sustained upswing in demand for a non-surgical solution.

  • Founded in 2024, BioSenic their lead product, JTA, is displaying lengthy intra-articular residence time and improved functional outcomes from preliminary clinical evaluations. This development has placed them in a position to disrupt the standard of traditional HA injections with enhanced compliance and relief. Their sole aim is to produce the next-generation hyaluronic acid viscosupplements with enhanced retention and viscosity.
  • Established in 2020, Articulate Biosciences pre‑seed technology targets cartilage‑preserving formulations showing improved functional outcomes with preliminary clinical observations. Their key aim is development of next‑generation biomimetic polymer viscosupplements that achieve extended pain relief and joint protection vs. conventional HA injections.

Top Player’s Company Profiles

  • Sanofi S.A. (France) 
  • Anika Therapeutics, Inc. (United States) 
  • SEIKAGAKU CORPORATION (Japan) 
  • Zimmer Biomet Holdings, Inc. (United States) 
  • Bioventus Inc. (United States) 
  • Fidia Farmaceutici S.p.A. (Italy) 
  • Ferring Pharmaceuticals (Switzerland) 
  • Johnson & Johnson (United States) 
  • Smith & Nephew plc (United Kingdom) 
  • Avanos Medical, Inc. (United States) 
  • LG Chem, Ltd. (South Korea) 
  • IBSA Institut Biochimique SA (Switzerland) 
  • Hoffmann-La Roche Ltd. (Switzerland) 
  • Teva Pharmaceutical Industries Ltd. (Israel) 
  • Viatris Inc. (United States) 
  • Lifecore Biomedical, LLC (United States) 
  • Aptissen SA (Switzerland) 
  • Chugai Pharmaceutical Co., Ltd. (Japan) 
  • Kolon TissueGene, Inc. (South Korea) 
  • TRB CHEMEDICA SA (Switzerland) 

Recent Developments in Viscosupplementation Market

  • In February 2025, LG Chem expanded its viscosity supplementation presence in the Asia-Pacific (APAC) region by launching non-animal derived hyaluronic acid injectables and increasing its local production capacity in South Korea and Vietnam. The new product line addresses increasing regional demand and a regulatory requirement to improve access for more patients, strengthen the region's supply resilience, and assurance of clinical quality supply.
  • In July 2024, Anika Therapeutics launched Hyalofast, a next-engineered hyaluronic acid injectable for osteoarthritis. Hyalofast provides patients with fewer injections and faster recovery times while providing enhanced convenience and learning opportunities. The expanded product suite ultimately strengthens Anika's position in orthopedic clinics around the world, which is timely as demand is increasing for minimally invasive treatments for joints and brief care pathways.
  • In March 2024, Smith & Nephew launched Synvisc‑One, a viscosupplement for knee osteoarthritis as a single-injection treatment to give extended pain relief and mobility benefits while reducing the procedural burden and increasing compliance. This introduction is congruent with the global trend in industry simplification, with an emphasis on patient-centric care in outpatient orthopedic practice.

Viscosupplementation Key Market Trends

Viscosupplementation Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

As per SkyQuest analysis, the global viscosupplementation industry is experiencing robust growth driven by the rising incidence of osteoarthritis, an aging population, and a rising tide of demand for minimally invasive treatment options. Technological innovations, primarily through AI & IoT, are disrupting the market by providing personalized treatment options, real-time monitoring of patient outcomes, and smart devices that increase the precision of injections. The above innovations increase patient adherence and clinical efficacy, propelling market growth. However, there are challenges in adoption due to inadequately high costs of treatment, reimbursement, and risk of adverse reactions.

Despite these restraints, AI-enabled diagnostics and IoT-based delivery systems are expected to help revolutionize viscosupplementation therapies with improved and less expensive access. Emerging markets remain a largely untapped opportunity, partly supported by better healthcare infrastructure and improved recognition of the technology provided. As new entrants and established players innovate and enhance their models, the viscosupplementation product market is positioned to develop in line with current expectations of patients and healthcare providers globally.

Report Metric Details
Market size value in 2024 USD 5.38 Billion
Market size value in 2033 USD 8.71 Billion
Growth Rate 5.5%
Base year 2024
Forecast period 2026-2033
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Introduction ,Single Injection ,Three Injection ,Five Injection
  • Application
    • Introduction ,Knee Osteoarthritis ,Hip Osteoarthritis ,Shoulder Osteoarthritis ,Other Applications
  • Source
    • Introduction ,Animal Source ,Non-Animal Source
  • End User
    • Introduction ,Hospitals ,Orthopedic Clinics/Ambulatory Surgical Centers (ASCS) ,Retail Pharmacies ,Online Pharmacies
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Sanofi S.A. (France) 
  • Anika Therapeutics, Inc. (United States) 
  • SEIKAGAKU CORPORATION (Japan) 
  • Zimmer Biomet Holdings, Inc. (United States) 
  • Bioventus Inc. (United States) 
  • Fidia Farmaceutici S.p.A. (Italy) 
  • Ferring Pharmaceuticals (Switzerland) 
  • Johnson & Johnson (United States) 
  • Smith & Nephew plc (United Kingdom) 
  • Avanos Medical, Inc. (United States) 
  • LG Chem, Ltd. (South Korea) 
  • IBSA Institut Biochimique SA (Switzerland) 
  • Hoffmann-La Roche Ltd. (Switzerland) 
  • Teva Pharmaceutical Industries Ltd. (Israel) 
  • Viatris Inc. (United States) 
  • Lifecore Biomedical, LLC (United States) 
  • Aptissen SA (Switzerland) 
  • Chugai Pharmaceutical Co., Ltd. (Japan) 
  • Kolon TissueGene, Inc. (South Korea) 
  • TRB CHEMEDICA SA (Switzerland) 
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Viscosupplementation Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Viscosupplementation Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Viscosupplementation Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Viscosupplementation Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Viscosupplementation Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Viscosupplementation Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

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FAQs

Global Viscosupplementation Market size was valued at USD 5.38 Billion in 2024 and is poised to grow from USD 5.68 Billion in 2025 to USD 8.71 Billion by 2033, growing at a CAGR of 5.5% during the forecast period (2026–2033). 

The global viscosupplementation market outlook is highly competitive, with market competitors like DePuy Synthes, Fidia Farmaceutici and Sanofi disrupt the market with differentiated formulations of hyaluronic acid (HA), ranging from single, to cross-linked and high-molecular-weight approaches with a goal of maximizing pain relief and minimizing frequency of injections. DePuy's MONOVISC and ORTHOVISC products are being positioned with education programs in orthopedic clinics. Fidia Farmaceutici has been creating preference for Hymovis, a two-injection product that is being developed for shoulder and ankle applications, with EMA approvals. 'Sanofi S.A. (France) ', 'Anika Therapeutics, Inc. (United States) ', 'SEIKAGAKU CORPORATION (Japan) ', 'Zimmer Biomet Holdings, Inc. (United States) ', 'Bioventus Inc. (United States) ', 'Fidia Farmaceutici S.p.A. (Italy) ', 'Ferring Pharmaceuticals (Switzerland) ', 'Johnson & Johnson (United States) ', 'Smith & Nephew plc (United Kingdom) ', 'Avanos Medical, Inc. (United States) ', 'LG Chem, Ltd. (South Korea) ', 'IBSA Institut Biochimique SA (Switzerland) ', 'Hoffmann-La Roche Ltd. (Switzerland) ', 'Teva Pharmaceutical Industries Ltd. (Israel) ', 'Viatris Inc. (United States) ', 'Lifecore Biomedical, LLC (United States) ', 'Aptissen SA (Switzerland) ', 'Chugai Pharmaceutical Co., Ltd. (Japan) ', 'Kolon TissueGene, Inc. (South Korea) ', 'TRB CHEMEDICA SA (Switzerland) '

The increasing prevalence of osteoarthritis, specifically for the older population, is one of the main factors driving the viscosupplementation market. With age comes the added risk of joint degeneration, thus non-surgical solutions for pain relief like hyaluronic acid injections are rapidly becoming in demand. This preference for minimally invasive non-surgical types of pain-relieving therapies over total joint replacements, also allows for market growth both in developed and developing countries alike.

Shift Toward Single-Injection and Long-Acting Formulations: A key trend driving viscosupplementation market is that Single-injection hyaluronic acid treatments are more commonly preferred by both consumers and providers because they provide convenience, less time in the clinic, and less procedural risk. However, with the advent of long-acting formulations, prolonged joint lubrication and pain relief can improve compliance and outcomes. These changes are consistent with larger changes in outpatient settings and provide a cost-effective method of managing osteoarthritis.

As per the global viscosupplementation market analysis, North America dominates the global viscosupplementation market because of its sophisticated healthcare structures, the prevalence of osteoarthritis in the region and the span of reimbursement. There is also an increasing prevalence of awareness for viscosupplementation therapy as treatment options and improvements in the single-injection product formulations continue to develop. Additionally, government support for viscosupplementation, as well as strong clinical trial networks, add to overall market market strength in the U.S. and Canada.
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