USD 2.10 Billion
Global Tangential Flow Filtration Market Size, Share, Growth Analysis, By Product(Single-use Tangential Flow Filtration Systems, Reusable Tangential Flow Filtration Systems), By Technology(Ultrafiltration, Microfiltration), By Application(Protein Purification, Vaccine and Viral Vectors), By End-use(Pharmaceutical & Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations) - Industry Forecast 2024-2031
Report ID:
SQMIG35H2128 |
Region:
Global |
Published Date: April, 2024
Pages:
219
|
Tables:
121 |
Figures:
77
Global Tangential Flow Filtration Market Insights
Global Tangential Flow Filtration Market size was valued at USD 2.10 Billion in 2022 and is poised to grow from USD 2.34 Billion in 2023 to USD 5.61 Billion by 2031, at a CAGR of 11.53% during the forecast period (2024-2031).
Tangential flow filtration technology is growing in popularity to meet the increased demand for biopharmaceuticals for the management of different diseases and degenerative diseases including diabetes, cancer, & rheumatoid arthritis. This trend is the primary factor driving the market. Tangential flow filtration's (TFF) advantages, such as its high performance & reproducible operations, as well as companies increasing involvement in the creation of fresh TFF products, are also having an effect on the market's growth.
Additionally, ongoing industry expenditures and encouraging government initiatives have led to facility expansions and active R&D for the creation of new tools and technologies that are used in the production of biopharmaceuticals. The mass manufacture of the COVID-19 vaccine and the rising demand for biopharmaceuticals have opened up a slew of new options for major firms. Additionally, the utilization of single-use TFF equipment among end-users has increased due to the growing acceptance of single-use biological processing equipment for the production of biopharmaceuticals. To address the rising demand for single-use technology required for the production of the COVID-19 vaccine, for instance, Pall Corporation invested a total of USD 114 million.
The additional advantages of TFF above traditional flow filtration add to the high utilization rate and continue to drive the market growth. A few benefits of TFF systems include increased flow rate, reduced product build-up, removing filter aids, simplified cleaning, and filter replacement. Additionally, because TFF is a continuous filtering process, it takes less time to run and is now automated thanks to technology improvements. Automated filtering systems extend the process's resilience and productivity by decreasing fouling of the membrane, which eventually lengthens the membrane's shelf life. These advantages have led to the use of TFF systems in the production of biopharmaceuticals. Several firms have also improved their marketplace presence and created cutting-edge technology. For instance, Repligen Corporation received a patent in 2021 for their Tangential Flow Depth Filtering (TFDF) filter, which offers a one-use solution with little hold-up volume and lots of flux. Over the forecast period, such advancements and breakthroughs in this field are anticipated to fuel industry expansion.
US Tangential Flow Filtration Market is poised to grow at sustainable CAGR for the next forecast year.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Microfiltration
Fastest Growth
Microfiltration
Growth Rate
11.53% CAGR
Global Tangential Flow Filtration Market ($ Bn)
Country Share for North America Region (%)
Global Tangential Flow Filtration Market By Technology ($ Bn)
Global Tangential Flow Filtration Market By Technology (%)
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Global Tangential Flow Filtration Market Segmental Analysis
The global tangential flow filtration market is segmented on the basis of product, technology, application, end-use, and region. Based on product, the market is segmented into Single-use Tangential Flow Filtration Systems, Reusable Tangential Flow Filtration Systems, Membrane Filters, and Filtration Accessories. In terms of technology, the market is segmented into Ultrafiltration, Microfiltration, Nanofiltration, and Others. Based on Application the market is segmented into Protein Purification, Vaccine and Viral Vectors, Antibody Purification, Raw Material Filtration, Others. Based on End-user the market is segmented into Pharmaceutical & Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations, Academic Institutes & Research Laboratories. Based on region the global Tangential Flow Filtration Market is segmented into North America, Europe, Asia-Pacific, South America, and MEA.
Tangential Flow Filtration Market Analysis by Product
The membrane filters had the biggest market share—more than 30% in 2022. The category is growing as a result of the ongoing use of filtering systems by diverse industries, the benefits of the TFF system above dead-end and normal flow filtration, and the availability of numerous filter types like PES, PVDF, PCTE, and PTFE. Additionally, the ability to scale upward and downward is powered by the ability to use different membrane pores & filtration regions for the desired operation.
Single-use TFF systems will experience a growth rate of 12.26% throughout the duration of the prediction. The market's growth will be aided by the growing use of single-use technologies by companies, contract organizations, and academic settings. Smaller footprints, quicker processing times, and less cross-contamination are just a few of the benefits that have propelled the market for disposable TFF systems. The predicted growth is further aided by the introduction of new single-use TFF systems. For instance, ABEC, Inc. stated the release date of their fresh single-use TFF device as 2021. In this item's launch, the company aims to increase downstream production by offering high flow rates and rapid processing times.
Tangential Flow Filtration Market Analysis by Technology
The microfiltration market had the greatest share—more than 30.0% in 2030. The extensive usage of microfiltration technologies during cell separation procedures greatly aids in this segment's income generating. Microfiltration membranes also provide solutions for problems including protein fractionation, microbial eradication, and treatment of other membranes, which supports the growth. Additionally, because the pore diameters of these membranes range from 0.1 to 10 m, this technology provides optimized flow, lessens the potential for fouling, and aids in the separation of particles that are suspended.
The market for nanofiltration is predicted to develop at the quickest rate between 2023 and 2030. Selective ion separation & end-stage sterilization are two common applications for nanofiltration technology, which makes use of pores in membranes with a size of 1 to 10 nm. Additionally, these membranes use less energy while producing a high flux at low pressures. Nanofiltration membranes, which exclude multivalent ions, microorganisms, proteins, and organic molecules while permitting only water and certain salts to pass through, will be the primary source of demand for this market sector in the future. Water purification, supply stream management, medicine formulation and filling, and water pollution control all make extensive use of this technique.
Global Tangential Flow Filtration Market By Technology , 2023 (%)
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Global Tangential Flow Filtration Market Regional Insights
North America had the highest revenue share (almost 40.0%) in 2022. Regional growth has been aided by the expansion of bioprocessing facilities to fulfill the demand for biotherapeutics, the rise in the prevalence of chronic diseases & genetic conditions, growing public knowledge of the safety of medical interventions, and the development of healthcare environments. In addition, having a helpful government promotes development. For instance, the budget for 2021 from the Government of Canada included around USD 0.7 billion (CAD 1 billion) in funding for the growth of life sciences and biomanufacturing companies. This financing is provided for a period of more than seven years through the Strategic Innovation Fund. In order to increase domestic demand for medicines and vaccines in Canada, Biovectra, a CDMO, upgraded its Nova Scotia biologics facility & constructed a new facility in Prince Edward Island.
Asia Pacific (APAC) is expected to see the fastest rate of growth during the forecast period. One of the main factors driving the industry's growth is the creation of CMOs in emerging economies like China, Japan, & South Korea, as well as the growing need for pharmaceuticals & biologics and the large inflow of investments from foreign and domestic companies. The rise of the TFF market in APAC will also be aided by the advancement of the healthcare system, the demand for reasonably priced medications, and the focus on modernizing therapies.
Global Tangential Flow Filtration Market By Geography, 2024-2031
- Largest
- Fastest
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Global Tangential Flow Filtration Market Dynamics
Tangential Flow Filtration Market Drivers
Increasing Demand for Biopharmaceuticals
- The growing demand for biopharmaceutical products, such as monoclonal antibodies, vaccines, and recombinant proteins, is a significant driver for the TFF market. TFF is widely used in the biopharmaceutical industry for the purification and concentration of these products.
Tangential Flow Filtration Market Restraints
High Initial Investment and Operational Costs
- The implementation of TFF systems can involve significant upfront costs for equipment, consumables, and infrastructure. Additionally, operational costs associated with maintenance, validation, and cleaning can be substantial. These factors may restrain the adoption of TFF, particularly for small and medium-sized enterprises with limited budgets.
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Global Tangential Flow Filtration Market Competitive Landscape
As a result of its advantages and swift adoption by bio-manufacturers, the industry has been expanding without end for the past few years. Key companies in the TFF market now have worthwhile chances thanks to the rising application in domains like immunology, microbiology, and protein purification procedures. A large product line of filtering products for a variety of applications has also led to considerable income generating. Players use a variety of strategic efforts, including alliances, acquisitions, new product launches, and collaborations, to achieve a competitive advantage.
For instance, Solaris Biotechnology Srl, a producer of bioprocessing equipment with headquarters in Italy, was purchased by Donaldson Company, Inc. in 2021 for USD 40.3 million (EUR 41 million). Since Solaris's portfolio comprised bioreactors, TFF structures, and fermenters, the acquisition increased the company's access to clients in the biopharmaceutical and life science industries. These business initiatives will expand the product line, increase the use of TFF goods in bioprocessing operations, or raise market rivalry, all of which will move the market forward.
Tangential Flow Filtration Market Top Player’s Company Profiles
- Thermo Fisher Scientific Inc.
- Danaher Corporation
- MilliporeSigma
- Repligen Corporation
- 3M Company
- Pall Corporation (a division of Danaher Corporation)
- Parker Hannifin Corporation
- Asahi Kasei Corporation
- Alfa Laval AB
- Eppendorf AG
- Spectrum Laboratories, Inc. (a subsidiary of Repligen Corporation)
- Cole-Parmer Instrument Company LLC
- GEA Group AG
- Novasep Holding S.A.S.
- Filtration Group Corporation
- Starlab Scientific Co., Ltd.
- Alfa Wassermann Separation Technologies S.p.A.
Tangential Flow Filtration Market Recent Developments
-
In January 2024, Verdot, downstream bioprocessing technology company announced the launch of its FlexiPro TFF, a multipurpose tangential flow filtration (TFF) GMP system, in response to rising industry demand for gene therapy, vaccine, and mRNA-based therapeutics.
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In November 2023, Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, announced the commercial launch of TangenX SC, the industry’s first holder-free, self-contained Tangential Flow Filtration (TFF) device. The technology is especially suited to the manufacture of biologics where fully closed systems are critical or ideal, including antibody drug conjugates (ADCs), viral vectors, nucleic acids and lipid nanoparticles, and can also be applied to monoclonal antibody, and recombinant protein production.
Global Tangential Flow Filtration Key Market Trends
- Increasing Adoption of Single-use TFF Systems: The market is witnessing a growing trend towards the use of single-use TFF systems. Single-use TFF offers several advantages, including reduced cross-contamination risk, simplified cleaning and validation processes, and increased operational flexibility. The convenience and cost-effectiveness of single-use systems are driving their adoption across various biopharmaceutical manufacturing processes.
- Rising Demand for High-capacity TFF Systems: With the increasing production volumes of biopharmaceuticals, there is a growing need for TFF systems with higher capacity and throughput. Market players are focusing on developing high-capacity TFF systems that can handle larger volumes of feedstock and improve process efficiency. These systems enable higher productivity and scalability, catering to the industry's demand for large-scale bioprocessing.
- Emergence of Integrated TFF Platforms: Integrated TFF platforms that combine multiple functionalities, such as TFF, viral clearance, and ultrafiltration, into a single system, are gaining traction in the market. These integrated platforms offer streamlined processes, reduced footprint, and improved process control. They enable efficient and seamless operation, reducing the need for multiple standalone systems and enhancing overall manufacturing efficiency.
- Adoption of Advanced TFF Membranes and Materials: Market players are continuously investing in research and development to improve TFF membrane technologies and develop new materials. There is a focus on developing membranes with enhanced selectivity, flux rates, and fouling resistance to optimize TFF processes. Novel materials and coatings are also being explored to address specific filtration challenges and improve overall performance.
Global Tangential Flow Filtration Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyzes the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.
According to our global tangential flow filtration market analysis, filtration technology is growing in popularity to meet the increased demand for biopharmaceuticals for the management of different diseases and degenerative diseases including diabetes, cancer, & rheumatoid arthritis. This trend is the primary factor driving the market. Tangential flow filtration's (TFF) advantages, such as its high performance & reproducible operations, as well as companies increasing involvement in the creation of fresh TFF products, are also having an effect on the market's growth.
| Report Metric | Details |
|---|---|
| Market size value in 2023 | USD 2.10 Billion |
| Market size value in 2031 | USD 5.61 Billion |
| Growth Rate | 11.53% |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
|
| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Global Tangential Flow Filtration Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Global Tangential Flow Filtration Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Global Tangential Flow Filtration Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Tangential Flow Filtration Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Tangential Flow Filtration Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Global Tangential Flow Filtration Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
Global Tangential Flow Filtration Market Report Snapshots
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