Top Next Generation Sequencing Companies

The increasing demand for efficient, precise, and inexpensive genomic analysis in clinical diagnostics, pharmaceutical R&D, and academic research is the primary driver behind the global next generation sequencing market. Decreased sequencing costs and improved sequencing platforms, library preparation kits, and bioinformatics tools are leading to greater adoption of NGS. There is an increasing incidence of cancer and rare genetic diseases, which has led health systems to adopt NGS technologies for early detection and precision oncology and companion diagnostics. There is also increased adoption and utilization of NGS technologies for reproductive health, including non-invasive prenatal testing (NIPT) and carrier screening.

Industry Overview

According to SkyQuest Technology “Next Generation Sequencing Market By Technology (WGS, Whole Exome Sequencing, Targeted Sequencing & Resequencing, and Others), By Product (Platform and Consumables), By End-Use (Academic Research, Clinical Research, Hospitals & Clinics, Pharma & Biotech Entities, and Other Users), By Region- Industry Forecast 2025-2032,” Global Next Generation Sequencing Market is projected to grow at a CAGR of over 14.3% by 2032, on account of urgent need for automating quantified data. Emerging applications of NGS in microbiology, infectious disease surveillance, and tracking outbreaks of pathogens are also contributing to market growth. Additionally, government funding and investment programs, genomics initiatives with large-scale whole genome sequencing, and partnerships between providers of sequencing technologies and clinical laboratories are all pushing the global market forward.

Top 10 Global Next Generation Sequencing Companies

1. Illumina, Inc.

Illumina, Inc. is the global leader in next-generation sequencing, known for its high-throughput sequencing platforms such as the NovaSeq, NextSeq, and MiSeq systems. The company has played a key role in reducing the cost of genome sequencing and promoting the use of genomics in research, clinical diagnostics, and precision medicine.

2. Thermo Fisher Scientific (NGS Division)

Thermo Fisher Scientific houses one of the most diverse life sciences portfolios in the world, with its Ion Torrent sequencing platforms forming the backbone of its NGS business. The company delivers targeted sequencing technologies, benchtop sequencers, a solid reagent portfolio, automated sample preparation systems, and integrated genomic analysis software.

3. BGI Genomics / MGI Tech

BGI Genomics is among the largest genomic service providers in the world, and MGI Tech, a subsidiary, is a significant NGS technology developer. The company provides well-priced, low-cost DNBSEQ sequencing platforms that are direct competitors to the global leaders based upon throughput, accuracy and price. BGI engages in large population genomic studies, infectious disease surveillance, reproductive health testing, and research sequencing.

4. Roche Sequencing Solutions

Roche Sequencing Solutions, a division of Roche Diagnostics, is dedicated to developing clinical-grade NGS technologies. The company offers target enrichment technologies, sequencing reagents, and platforms for disease-specific applications, including oncology, infectious diseases, and hereditary genetics.

5. Oxford Nanopore Technologies

Oxford Nanopore Technologies is a leader in long-read sequencing and manufactures nanopore-based, real-time sequencing platforms. Products such as the MinION, GridION, and PromethION allow for long-read sequencing to facilitate comprehensive genome assembly, epigenetic studies, and structural variant analysis.

6. Qiagen (NGS Division)

Qiagen is a leading supplier of NGS workflow components, specifically sample preparation technologies, library preparation kits, and bioinformatics tools. Qiagen does not supply large sequencing instruments, but its consumables exist in NGS workflows globally. Qiagen's primary NGS-related products include the QIAseq library prep systems and CLC Genomics Workbench software.

7. Pacific Biosciences (PacBio)

Pacific Biosciences manufactures high-fidelity long-read sequencing technologies and offers advanced systems based on Single Molecule Real-Time (SMRT) sequencing. PacBio's HiFi sequencing has excellent accuracy and is a powerful approach to genome assembly, structural variant analysis, genetics of rare disease, metagenomics, and full-length transcriptome.

8. Agilent Technologies

Agilent Technologies is critically important to NGS workflows with its comprehensive suite of sample preparation and target enrichment products. Agilent’s SureSelect and SureSeq platforms, for example, are used for exome sequencing, cancer panel testing, and target gene analysis in the laboratory. Agilent also has automation systems, reagents, and software tools that complete genomics laboratories in the laboratory space. 

9. Genewiz

Genewiz, a part of Azenta Life Sciences, provides sequencing services globally, including NGS, Sanger sequencing, synthetic biology, and microbiome analysis. The company serves as a solution provider for organizations engaged in pharmaceutical, biotech, and academic research by offering high-quality sequencing and timely and reliable data analysis and project management for large genomic studies.

10. PerkinElmer (Life Sciences Division)

PerkinElmer’s life sciences division provides multiple technologies that support the NGS workflows, including automated sample preparation systems, library preparation systems, and integrated genomic analysis systems commercially known as their life sciences division.

Other Leading Global Next Generation Sequencing Companies

• Integrated DNA Technologies (IDT)
• Takara Bio
• Bio-Rad Laboratories
• Beckman Coulter Life Sciences
• Fluidigm (Standard BioTools)
• Twist Bioscience
• 10x Genomics
• Element Biosciences
• Ultima Genomics
• SeqWell
• PierianDx
• Strand Life Sciences

Conclusion

The global next generation sequencing market is on a path of sustained growth as the technology continues to transition from research settings to established practices in clinical medicine. Growing adoption of NGS across oncology, reproductive genetics, infectious disease diagnostics, and personalized medicine indicates its increasing importance in improving the accuracy of patient diagnoses and treatment decisions has gained popularity. Continued innovation in sequencing platforms, AI-enabled data analysis, and automation simplifies operational workflows, making NGS more accessible for laboratories across the globe. Once again, the increasing investment from government, healthcare systems and private organizations in large-scale genomics programs is expected to further mature the market and is fueled by strong demand for high-throughput, cost-effective and clinically relevant sequencing options. Overall, NGS technology is moving from a research tool to a key technology that will drive the future of precision healthcare.