Global N-Acetylcysteine Market

N-Acetylcysteine Market Size, Share, Growth Analysis, By Type(Spray, Tracheal Drip, Tablet), By Application(Medicine, Nutritional Supplements, Others), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35I2290 | Region: Global | Published Date: July, 2001
Pages: 157 |Tables: 63 |Figures: 75

N-Acetylcysteine Market Insights

N-Acetylcysteine Market size was valued at USD 1083.78 million in 2019 and is poised to grow from USD 1316.79 million in 2023 to USD 7598.08 million by 2031, growing at a CAGR of 21.5% in the forecast period (2024-2031).

Acetylcysteine (NAT) is a chemical used to treat paracetamol (acetaminophen) overdoses and to release thick mucus in people suffering from chronic respiratory ailments such as pneumonia and bronchitis. Lactobezoar can be treated in newborns using it. It can be injected, consumed, or inhaled as a mist. Many individuals use it as a dietary supplement. Nausea and vomiting are frequent adverse effects when taken by mouth. After taking the drug, some people experience skin redness and irritation. Non-immune anaphylaxis is also conceivable. It is considered safe during pregnancy. To combat paracetamol overdose, it raises glutathione levels, an antioxidant that neutralises paracetamol's harmful breakdown products. It functions as a mucolytic when inhaled, lowering mucus thickness.

US N-Acetylcysteine Market  is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 1083.78 million

Largest Segment

Medicine

Fastest Growth

Medicine

Growth Rate

21.5% CAGR

Global N-Acetylcysteine Market ($ Bn)
Country Share for North America Region (%)

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N-Acetylcysteine Market Segmental Analysis

The Global N-Acetylcysteine Market is segmented based on the Component, Type, Application, and Region. Based on the Type, the Global N-Acetylcysteine Market is segmented as Spray and Tracheal Drip and Tablet. Based on the Application, the Global N-Acetylcysteine Market is segmented as Medicine, Nutritional Supplements, and Tablet. Based on Region it is categorized into North America, Europe, Asia-Pacific, Latin America, and MEA.

N-Acetylcysteine Market Analysis by Application

In terms of type, tablet dominated the global market in 2021 and is projected to show a similar trend over the forecast period. Rising demand for N-Acetylcysteine for the treatment of acetaminophen intoxication, as well as growing usage of N-Acetylcysteine in the healthcare industry, are projected to help the market. The demand for acetaminophen is growing, as are the cases of paracetamol overdose. Indeed, in countries such as the United Kingdom, Australia, and the United States, the prevalence of paracetamol overdose is higher than the rate of paracetamol itself. Paracetamol poisoning instances, for example, have increased by more than 40% in the United Kingdom and Australia during the previous decade.

Global N-Acetylcysteine Market By Application, 2023 (%)

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N-Acetylcysteine Market Regional Insights

North America is predicted to have the greatest market share due to considerable R&D in the medical industry. The business is booming as researchers work to find a treatment for HIV. Because of China's enormous manufacturing base, Asia Pacific is expected to develop significantly. The use of n-acetylcysteine for paracetamol intoxication is predicted to drive a significant increase in Europe. Eastern and southern Africa will account for over 52% of all HIV-infected persons by 2020. Because of the growing number of HIV patients, Latin America, the Middle East, and Africa will experience a significant increase by the end of the projection period.

Global N-Acetylcysteine Market By Region, 2024-2031
  • Largest
  • Fastest

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N-Acetylcysteine Market Dynamics

N-Acetylcysteine Market Driver

Growing Demand from The Health Industry

  • N-acetyl cysteine is an antioxidant that may help prevent cancer. It is a medication used by doctors to treat acetaminophen (Tylenol) toxicity. It acts by binding the toxic forms of acetaminophen produced in the liver. N-acetyl cysteine is often used to treat coughs and other respiratory diseases. It is also claimed to treat the flu, dry eyes, and a variety of other illnesses, although there is no scientific evidence to back up many of these claims. There is also no convincing evidence to support the use of N-acetyl cysteine in the treatment of COVID-19.

N-Acetylcysteine Market Restraint

N-Acetylcysteine Side Effects

  • N-acetylcysteine is well tolerated at doses of 1,200 mg twice daily or less. Side effects are uncommon at these doses; however, they may include nausea, vomiting, diarrhoea, a brief skin rash, flushing, epigastric discomfort, and constipation. N-acetylcysteine is sometimes poorly tolerated at much higher dosages used to treat acetaminophen overdose, with adverse symptoms such as headache, tinnitus, urticaria, rash, chills, fever, and anaphylactoid responses (pseudoanaphylaxis). N-acetylcysteine greatly enhances the impact of nitroglycerin and similar drugs, and therefore should be used with caution in patients taking these treatments who are at risk of hypotension.

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N-Acetylcysteine Market Competitive Landscape

The primary means through which the corporation competes in the global market are innovation and commercial expansion. To compete, these businesses use a range of business methods, such as long-term supply agreements with several distribution channels. Major corporations have increasingly concentrated on entering Asian markets in recent years due to the availability of a target consumer base in the region.

N-Acetylcysteine Market Top Player's Company Profiles

  • Zambon Company S.p.A.
  • Wuxi Jinghai Amino Acid Co., Ltd.
  • Pharma Nord ApS
  • Nacalai Tesque, Inc.
  • Manus Aktteva Biopharma LLP
  • Sigma-Aldrich Corporation
  • Taizhou Tianhong Biochemistry Technology Co., Ltd.
  • Alfa Aesar
  • Acetylcysteine China Inc.
  • Zhejiang Kangle Pharmaceutical Co., Ltd.
  • Wuhan Wuyao Pharmaceutical Co., Ltd.
  • Shijiazhuang Haitian Amino Acid Co., Ltd.
  • Jiangsu Gedi Biological Engineering Co., Ltd.
  • Nantong Baihua Bio-pharmaceutical Co., Ltd.
  • Changzhou Yabang-QH Pharmachem Co., Ltd.
  • Anhui Leafchem Co., Ltd.
  • Huahai Pharmaceutical Co., Ltd.
  • Hebei Guangren Pharmaceutical Technology Co., Ltd.
  • Sichuan Mingxin Pharmaceutical Co., Ltd.
  • Hangzhou Hyper Chemicals Limited

N-Acetylcysteine Market Recent Developments

  • In April 2022, CMS I-neb® by Zambon received FDA Breakthrough Therapy Designation in Patients with Non-Cystic Fibrosis Bronchiectasis from Zambon (NCFB). CMS I-neb® is an experimental inhalation medication that is aimed to deliver precise concentrations of medicine directly to the site of illness while minimizing systemic exposure, which can cause toxicity and adverse effects.
  • In 2019, Zambon has finalised its transformative purchase of Breath Therapeutics, which is developing a treatment for the rare respiratory condition Bronchiolitis Obliterans Syndrome.

N-Acetylcysteine Key Market Trends

  • NAC research is incredibly broad, spanning from cell-free systems to living organisms. On the one hand, there is the notion that administering NAC in the context of human illness can be helpful. Much research has been conducted to investigate the pharmacological application of NAC in animal illness models and clinical trials. Beyond its original applications as a mucolytic agent and an antidote to paracetamol overdose, subsequent research has looked into its possible utility in a variety of different pathophysiological settings, including mental and neurological illnesses, as well as coronavirus disease 2019.
  • On the other side, there is the possibility of employing NAC as a tool for removing oxidants (scavenging) in cell culture or animal research. NAC is frequently regarded as a general "antioxidant," and many researchers who use or test NAC believe that it reduces reactive oxygen species (ROS) levels and alleviates "oxidative stress," whatever these umbrella phrases may signify in any given circumstance.

N-Acetylcysteine Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by robust Secondary Desk research.

According to our Global N-Acetylcysteine Market Analysis, With the efficient control of the Covid-19 outbreak, sales of Acetylcysteine in the Chinese market will increase from 2022 to 2028. Furthermore, with the advent of additional manufacturers, the price of acetylcysteine is likely to fall. There is opportunity for expansion in terms of both sales volume and sales.

Report Metric Details
Market size value in 2023 USD 1083.78 million
Market size value in 2031 USD 7598.08 million
Growth Rate 21.5%
Forecast period 2024-2031
Forecast Unit (Value) USD Million
Segments covered
  • Type
    • Spray, Tracheal Drip, Tablet
  • Application
    • Medicine, Nutritional Supplements, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Zambon Company S.p.A.
  • Wuxi Jinghai Amino Acid Co., Ltd.
  • Pharma Nord ApS
  • Nacalai Tesque, Inc.
  • Manus Aktteva Biopharma LLP
  • Sigma-Aldrich Corporation
  • Taizhou Tianhong Biochemistry Technology Co., Ltd.
  • Alfa Aesar
  • Acetylcysteine China Inc.
  • Zhejiang Kangle Pharmaceutical Co., Ltd.
  • Wuhan Wuyao Pharmaceutical Co., Ltd.
  • Shijiazhuang Haitian Amino Acid Co., Ltd.
  • Jiangsu Gedi Biological Engineering Co., Ltd.
  • Nantong Baihua Bio-pharmaceutical Co., Ltd.
  • Changzhou Yabang-QH Pharmachem Co., Ltd.
  • Anhui Leafchem Co., Ltd.
  • Huahai Pharmaceutical Co., Ltd.
  • Hebei Guangren Pharmaceutical Technology Co., Ltd.
  • Sichuan Mingxin Pharmaceutical Co., Ltd.
  • Hangzhou Hyper Chemicals Limited
Customization scope

Free report customization with purchase. Customization includes:-

  • Segments by type, application, etc
  • Company profile
  • Market dynamics & outlook
  • Region

Historical Year 2019

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on N-Acetylcysteine Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on N-Acetylcysteine Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the N-Acetylcysteine Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the N-Acetylcysteine Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the N-Acetylcysteine Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the N-Acetylcysteine Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

N-Acetylcysteine Market size was valued at USD 1083.78 million in 2019 and is poised to grow from USD 1316.79 million in 2023 to USD 7598.08 million by 2031, growing at a CAGR of 21.5% in the forecast period (2024-2031).

The primary means through which the corporation competes in the market are innovation and commercial expansion. To compete, these businesses use a range of business methods, such as long-term supply agreements with several distribution channels. Major corporations have increasingly concentrated on entering Asian markets in recent years due to the availability of a target consumer base in the region. 'Zambon Company S.p.A.', 'Wuxi Jinghai Amino Acid Co., Ltd.', 'Pharma Nord ApS', 'Nacalai Tesque, Inc.', 'Manus Aktteva Biopharma LLP', 'Sigma-Aldrich Corporation', 'Taizhou Tianhong Biochemistry Technology Co., Ltd.', 'Alfa Aesar', 'Acetylcysteine China Inc.', 'Zhejiang Kangle Pharmaceutical Co., Ltd.', 'Wuhan Wuyao Pharmaceutical Co., Ltd.', 'Shijiazhuang Haitian Amino Acid Co., Ltd.', 'Jiangsu Gedi Biological Engineering Co., Ltd.', 'Nantong Baihua Bio-pharmaceutical Co., Ltd.', 'Changzhou Yabang-QH Pharmachem Co., Ltd.', 'Anhui Leafchem Co., Ltd.', 'Huahai Pharmaceutical Co., Ltd.', 'Hebei Guangren Pharmaceutical Technology Co., Ltd.', 'Sichuan Mingxin Pharmaceutical Co., Ltd.', 'Hangzhou Hyper Chemicals Limited'

N-acetyl cysteine is an antioxidant that may help prevent cancer. It is a medication used by doctors to treat acetaminophen (Tylenol) toxicity. It acts by binding the toxic forms of acetaminophen produced in the liver. N-acetyl cysteine is often used to treat coughs and other respiratory diseases. It is also claimed to treat the flu, dry eyes, and a variety of other illnesses, although there is no scientific evidence to back up many of these claims. There is also no convincing evidence to support the use of N-acetyl cysteine in the treatment of COVID-19.

NAC research is incredibly broad, spanning from cell-free systems to living organisms. On the one hand, there is the notion that administering NAC in the context of human illness can be helpful. Much research has been conducted to investigate the pharmacological application of NAC in animal illness models and clinical trials. Beyond its original applications as a mucolytic agent and an antidote to paracetamol overdose, subsequent research has looked into its possible utility in a variety of different pathophysiological settings, including mental and neurological illnesses, as well as coronavirus disease 2019.

North America is predicted to have the greatest market share due to considerable R&D in the medical industry. The business is booming as researchers work to find a treatment for HIV. Because of China's enormous manufacturing base, Asia Pacific is expected to develop significantly. The use of n-acetylcysteine for paracetamol intoxication is predicted to drive a significant increase in Europe. Eastern and southern Africa will account for over 52% of all HIV-infected persons by 2020. Because of the growing number of HIV patients, Latin America, the Middle East, and Africa will experience a significant increase by the end of the projection period.

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Global N-Acetylcysteine Market

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