USD 1.34 billion
Report ID: SQSG35J2010 | Region: Global | Published Date: April, 2023 | Pages: 278 | Tables: 92 | Figures: 76
In Situ Hybridization ISH Market size was valued at USD 1.34 billion in 2021 and is poised to grow from USD 1.44 billion in 2022 to USD 2.42 billion by 2030, growing at a CAGR of 6.9% in the forecast period (2023-2030).
Nucleic acids can be found and localized in cells, histological sections, and other biological samples using the molecular biology technique known as in-situ hybridization (ISH). It has many uses in molecular diagnosis, gene editing, and recombinant DNA technology because it enables scientists to observe how nucleic acids are distributed throughout the genome of the target organism. Due to ISH's high sensitivity, accurate localization, and effective quantification of sample nucleic acids, as well as its use in more and more fields including molecular biology, immunology, developmental biology, hematopathology, and phylogenetic analysis, the market is growing in terms of revenue.
Researchers have been able to learn more about disease prognosis, drug discovery and development, and the use of biomarkers through the detection of mRNA molecules and the study of the functional state of cells, among other major applications. Several research institutions and organizations have engaged in extensive R&D over the past few years to create a technology that can analyze the molecular profiles of individual cells. For instance, Proximity Ligation in situ Hybridization, an in situ hybridization method developed by Bio-protocol. The method is praised for its high performance, affordability, rapid multiplexing, and ease of use.
US In Situ Hybridization ISH Market is poised to grow at a sustainable CAGR for the next forecast year.
Global Market Size
USD 1.34 billion
Fluorescent In Situ Hybridization (FISH)
Chromogenic In Situ Hybridization (CISH)
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Global in situ hybridization (ISH) market is segmented based on the Technology, Product, Application, and region. Based on the Technology, the Global In Situ Hybridization (ISH) Market is segmented as FISH, and CISH. Based on the Product, the Global In Situ Hybridization ISH Market is segmented as Instruments, Kits & Probes, Software, and Service. Based on Application, the Global In Situ Hybridization ISH Market is segmented as Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, and Other. Based on Region it is categorized into North America, Europe, Asia-Pacific, Latin America, and MEA.
In Situ Hybridization ISH Market Analysis by Technology
Based on the Technology, the in situ hybridization ISH market is bifurcated into FISH, and CISH. The market share that belongs to FISH is the largest. This can be attributed to the numerous applications, such as the ability to diagnose congenital illnesses like Down syndrome and Edwards syndrome. The use of FISH technology has increased as a result of the rising prevalence and diagnosis of these diseases, which is anticipated to hasten market expansion. Due to its advantages over FISH in terms of cost, dependability, and practicality, the CISH market segment has also amassed a sizeable portion of in situ hybridization over time. With the help of the technology, conventional peroxidase reactions can detect copies of the HER-2/neu oncogene. The CISH market is expected to grow at a faster rate than average over the course of the forecast period due to rising acceptance of CISH technology for HPV genotyping on cervical smears.
In Situ Hybridization ISH Market Analysis by Product
Based on Product the in situ hybridization ish market is segmented into Instruments, Kits & Probes, Software, and Service. The Instruments category held the most market share. The growing networks of diagnostic and research laboratories are responsible for the rising demand for instruments. In situ hybridization is also expected to grow as a result of an increase in the number of strategic initiatives taken by the players to diversify their product offerings. As an illustration, in April 2021, Bio-Techne Corporation declared that it would release new DNA scope assays and RNAscope technology in the commercial market. It will be used to identify changes in DNA's copy number and structural makeup. Launches of such new products would support market expansion.
In Situ Hybridization ISH Market Analysis by Application
Based on Application the in situ hybridization ISH market is segmented into Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, and Other. The Cancer category held the most market share. It is anticipated that the growth will be fueled by an increase in the incidence rate of cancer cases. Around 1.9 million new cases of cancer are anticipated to be reported in the US in 2021, according to data released by the American Cancer Society. The need for in situ hybridization techniques for quick and accurate diagnosis is high due to the increase in cancer cases. Leading causes of cancer include an aging population, an increase in unhealthy lifestyles, poor health conditions, and the environment. Numerous organizations conduct research and support the advancement of cancer treatments. For instance, the grant program for cancer research at the American Institute for Cancer Research funded roughly 110 million USD in 2020–21.
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North America is expected to control the in situ hybridization (ISH) market share. The presence of a sizable number of market participants and the regional government's encouragement of research projects are both responsible for the region's growth. Throughout the forecast period, the region will continue to dominate due to high healthcare costs and strict FDA and Health Canada regulations. The most patents are in the North American market, while the Asia-Pacific market has a higher marginal increase than other markets. Health Canada-funded research institutions and projects are likely to have a small but positive impact on the market. The market is anticipated to grow the fastest in Asia Pacific during the anticipated period. Over the course of the forecast period, increasing the involvement of local authorities in R&D is anticipated to be the main market driver. In the Asia Pacific region, China and India have the two fastest-growing economies.
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In Situ Hybridization ISH Market Driver
In Situ Hybridization ISH Market Restraint
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Global in situ hybridization (ISH) market is highly competitive and somewhat fragmented. To maintain a competitive edge, the major industry participants are continually implementing various growth strategies. Innovations, mergers, and acquisitions, collaborations and partnerships are adopted by these players to thrive in the competitive market. In order to provide industries with the most effective and economical solutions, the major market players are also continually concentrating on R&D.
In Situ Hybridization ISH Market Top Player's Company Profiles
In Situ Hybridization ISH Market Recent Developments
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by the robust Secondary Desk research.
According to our Global In Situ Hybridization (ISH) Market Analysis, in terms of Technology, The market share that belongs to FISH is the largest. This can be attributed to the numerous applications, such as the ability to diagnose congenital illnesses like Down syndrome and Edwards syndrome. In terms of application, The Cancer category held the most market share. It is anticipated that the growth will be fueled by an increase in the incidence rate of cancer cases.
|Market size value in 2021||USD 1.34 billion|
|Market size value in 2030||USD 1.44 billion|
|Forecast Unit (Value)||USD Billion|
|Regions covered||North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)|
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For the Global In Situ Hybridization ISH Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global In Situ Hybridization ISH Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
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