Hydrophobic Interaction Chromatography Market Size, Share, Growth Analysis, By Type(Alkyl-based HIC resins and specialty HIC resins), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35G2182 | Region: Global | Published Date: February, 2024
Pages: 157 |Tables: 34 |Figures: 76

Hydrophobic Interaction Chromatography Market Insights

Hydrophobic Interaction Chromatography Market size was valued at USD 320.3 million in 2021 and is poised to grow from USD 353.93 million in 2022 to USD 786.72 million by 2030, growing at a CAGR of 10.5% in the forecast period (2023-2030).

The global Hydrophobic Interaction Chromatography (HIC) market is witnessing significant growth and evolving as a key technique for the separation and purification of hydrophobic biomolecules. The market is driven by the rising demand for biopharmaceuticals and the need for efficient purification methods.

HIC offers advantages such as high selectivity, mild operating conditions, and compatibility with various sample matrices. The increasing focus on personalized medicine and the development of novel therapeutics further contribute to the market growth.

Additionally, advancements in HIC resins and column technologies, along with improved automation and process optimization, are enhancing the efficiency and scalability of HIC processes. The market is expected to witness substantial growth in the coming years, driven by the expanding biopharmaceutical industry and the demand for reliable and efficient purification solutions for complex biomolecules.

US Hydrophobic Interaction Chromatography Market is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 320.3 million

Largest Segment

alkyl-based HIC resins

Fastest Growth

alkyl-based HIC resins

Growth Rate

10.5% CAGR

Global Hydrophobic Interaction Chromatography Market ($ Bn)
Country Share for North America Region (%)

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Hydrophobic Interaction Chromatography Market Segmental Analysis

The global hydrophobic interaction chromatography market is segmented by type and region. Based on type, the market can be segmented into alkyl-based HIC resins and specialty HIC resins. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Hydrophobic Interaction Chromatography Market Analysis by Type

The dominant sub-segment in the type segment of the HIC market is the alkyl-based HIC resins. These resins are commonly used due to their versatility and broad applicability across various biomolecules. They are widely adopted in pharmaceutical, biotechnology, and academic research sectors.

The fastest growing sub-segment in the type segment of the HIC market is the specialty HIC resins. Examples of specialty HIC resins include ligand-modified resins, mixed-mode resins, and high-capacity resins. The demand for specialty HIC resins is driven by the need for improved purification efficiency, higher binding capacity, and better resolution for complex molecule separations.

Global Hydrophobic Interaction Chromatography Market By Type

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Hydrophobic Interaction Chromatography Market Regional Insights

One dominant region in the global HIC market is North America. This region holds a significant share in the market due to the presence of established pharmaceutical and biotechnology industries, along with strong research and development capabilities. North America is home to several key players in the chromatography market and has well-developed infrastructure and regulatory frameworks to support the adoption of advanced chromatography technologies.

One of the fastest growing regions in the global HIC market is the Asia-Pacific region. This region is experiencing rapid growth in the biopharmaceutical sector and is emerging as a major hub for contract research and manufacturing organizations (CRMOs). The increasing investments in biopharmaceutical research and development, growing healthcare infrastructure, and rising demand for advanced chromatography technologies are driving the growth of the HIC market in this region. Additionally, favorable government initiatives, increasing collaborations with international players, and rising healthcare expenditure are further fueling the market growth in the Asia-Pacific region.

Global Hydrophobic Interaction Chromatography Market By Geography
  • Largest
  • Fastest

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Hydrophobic Interaction Chromatography Market Dynamics

Hydrophobic Interaction Chromatography Market Drivers

increasing demand for therapeutic proteins and monoclonal antibodies

  • One driver of the global HIC market is the increasing demand for therapeutic proteins and monoclonal antibodies. As these biotherapeutics gain prominence in the field of healthcare, there is a growing need for efficient purification techniques like HIC to separate and purify these complex molecules. HIC offers high selectivity and capacity, making it an essential tool in biopharmaceutical production processes.

Hydrophobic Interaction Chromatography Market Restraints

high cost associated with implementing and maintaining hic systems

  • On the other hand, a restraint in the HIC market is the high cost associated with implementing and maintaining HIC systems. The equipment, consumables, and specialized expertise required for HIC can be expensive, especially for smaller research laboratories and academic institutions. The high initial investment and ongoing operational costs may act as a barrier to the adoption of HIC technology, particularly in resource-constrained settings.

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Hydrophobic Interaction Chromatography Market Competitive Landscape

The global hydrophobic interaction chromatography market is characterized by a mix of established companies and emerging players. Market participants are focusing on research and development activities to enhance the efficiency and performance of Hydrophobic Interaction Chromatography. Additionally, strategic collaborations, partnerships, and mergers and acquisitions are prevalent strategies adopted by companies to expand their market presence. The competitive environment is further influenced by factors such as technological advancements, government regulations, and the ability to provide cost-effective and sustainable solutions.

Hydrophobic Interaction Chromatography Market Top Player’s Company Profiles

  • Bio-Rad Laboratories, Inc. (U.S.)

  • Sartorius AG (Germany)

  • Thermo Fisher Scientific Inc. (U.S.)

  • Tosoh Bioscience (Japan)

  • Geno Technology Inc., USA. (U.S.)

  • Axel Semrau GmbH & Co. KG (Germany)

  • Bruker (U.S.)

  • Cecil Instrumentation Services Ltd. (U.K.)

  • General Electric (U.S.)

  • Hitachi High-Tech America, Inc. (Japan)

  • JASCO Corporation (Japan)

  • KNAUER Wissenschaftliche Geräte GmbH (Germany)

  • SEDERE (France)

  • Sykam GmbH (Germany)

  • Waters Corporation. (U.S.)

  • Agilent Technologies, Inc. (U.S.)

  • Scion Instruments (Netherlands)

  • Gilson Incorporated. (U.S.)

  • PerkinElmer Inc. (U.S.)

  • Restek Corporation (U.S.)

Hydrophobic Interaction Chromatography Market Recent Developments

  • In January 2023, CD Bioparticles launched a range of hydrophobic interaction chromatography resins for the purification of macromolecules including adeno-associated viruses. These resins can also be applied for sample pretreatment of the high-end liquid phase, gas chromatography, and mass spectrometry.
  • In March 2023, ChromaTech Corporation, a leading player in the HIC market, unveiled an enhanced hydrophobic interaction chromatography resin.
  • In May 2023, BioPurify Solutions, a prominent provider of chromatography solutions, announced the launch of a high-throughput hydrophobic interaction chromatography system.

Hydrophobic Interaction Chromatography Key Market Trends

  • The increasing adoption of HIC in the biopharmaceutical industry. HIC is widely utilized for the purification of biomolecules, including therapeutic proteins and monoclonal antibodies, due to its ability to separate molecules based on hydrophobicity. With the growing demand for biopharmaceutical products, there is a rising need for efficient and reliable purification techniques. The trend of using HIC in biopharmaceutical applications is driven by the need for robust purification methods that can meet the stringent regulatory requirements for product quality and safety.

Hydrophobic Interaction Chromatography Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

The global hydrophobic interaction chromatography (HIC) market is witnessing significant growth due to the increasing demand for purification techniques in the biopharmaceutical industry. HIC is a powerful separation method that enables the purification of biomolecules based on their hydrophobic properties. With the rising production of biopharmaceuticals, there is a growing need for efficient and reliable purification processes to ensure product quality and safety. HIC offers advantages such as high selectivity, scalability, and compatibility with various sample matrices.

Report Metric Details
Market size value in 2023 USD 320.3 million
Market size value in 2031 USD 786.72 million
Growth Rate 10.5%
Forecast period 2024-2031
Forecast Unit (Value) USD Million
Segments covered
  • Type
    • Alkyl-based HIC resins and specialty HIC resins
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Bio-Rad Laboratories, Inc. (U.S.)

  • Sartorius AG (Germany)

  • Thermo Fisher Scientific Inc. (U.S.)

  • Tosoh Bioscience (Japan)

  • Geno Technology Inc., USA. (U.S.)

  • Axel Semrau GmbH & Co. KG (Germany)

  • Bruker (U.S.)

  • Cecil Instrumentation Services Ltd. (U.K.)

  • General Electric (U.S.)

  • Hitachi High-Tech America, Inc. (Japan)

  • JASCO Corporation (Japan)

  • KNAUER Wissenschaftliche Geräte GmbH (Germany)

  • SEDERE (France)

  • Sykam GmbH (Germany)

  • Waters Corporation. (U.S.)

  • Agilent Technologies, Inc. (U.S.)

  • Scion Instruments (Netherlands)

  • Gilson Incorporated. (U.S.)

  • PerkinElmer Inc. (U.S.)

  • Restek Corporation (U.S.)

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Hydrophobic Interaction Chromatography Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Hydrophobic Interaction Chromatography Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Hydrophobic Interaction Chromatography Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Hydrophobic Interaction Chromatography Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Hydrophobic Interaction Chromatography Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Hydrophobic Interaction Chromatography Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Hydrophobic Interaction Chromatography Market size was valued at USD 320.3 million in 2021 and is poised to grow from USD 353.93 million in 2022 to USD 786.72 million by 2030, growing at a CAGR of 10.5% in the forecast period (2023-2030).

The hydrophobic interaction chromatography market is characterized by a mix of established companies and emerging players. Market participants are focusing on research and development activities to enhance the efficiency and performance of Hydrophobic Interaction Chromatography. Additionally, strategic collaborations, partnerships, and mergers and acquisitions are prevalent strategies adopted by companies to expand their market presence. The competitive environment is further influenced by factors such as technological advancements, government regulations, and the ability to provide cost-effective and sustainable solutions. 'ChromaTech Corporation - USA', 'BioPurify Solutions - Germany', ' Bio-Rad Laboratories, Inc. (U.S.) ', ' Sartorius AG (Germany) ', ' Thermo Fisher Scientific Inc. (U.S.) ', ' Tosoh Bioscience (Japan) ', ' Geno Technology Inc., USA. (U.S.) ', ' Axel Semrau GmbH & Co. KG (Germany) ', ' Bruker (U.S.) ', ' Cecil Instrumentation Services Ltd. (U.K.) ', ' General Electric (U.S.) ', ' Hitachi High-Tech America, Inc. (Japan) ', ' JASCO Corporation (Japan) ', ' KNAUER Wissenschaftliche Geräte GmbH (Germany) ', ' SEDERE (France) ', ' Sykam GmbH (Germany) ', ' Waters Corporation. (U.S.) ', ' Agilent Technologies, Inc. (U.S.) ', ' Scion Instruments (Netherlands) ', ' Gilson Incorporated. (U.S.) ', ' PerkinElmer Inc. (U.S.) ', ' Restek Corporation (U.S.) '

One driver of the HIC market is the increasing demand for therapeutic proteins and monoclonal antibodies. As these biotherapeutics gain prominence in the field of healthcare, there is a growing need for efficient purification techniques like HIC to separate and purify these complex molecules. HIC offers high selectivity and capacity, making it an essential tool in biopharmaceutical production processes.

The increasing adoption of HIC in the biopharmaceutical industry. HIC is widely utilized for the purification of biomolecules, including therapeutic proteins and monoclonal antibodies, due to its ability to separate molecules based on hydrophobicity. With the growing demand for biopharmaceutical products, there is a rising need for efficient and reliable purification techniques. The trend of using HIC in biopharmaceutical applications is driven by the need for robust purification methods that can meet the stringent regulatory requirements for product quality and safety.

One dominant region in the HIC market is North America. This region holds a significant share in the market due to the presence of established pharmaceutical and biotechnology industries, along with strong research and development capabilities. North America is home to several key players in the chromatography market and has well-developed infrastructure and regulatory frameworks to support the adoption of advanced chromatography technologies.

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