Global Growth Hormone Deficiency Market

Global Growth Hormone Deficiency Market Size, Share, Growth Analysis, By Application(Pediatric growth hormone deficiency, Idiopathic short stature), By Route of Administration(Subcutaneous, Intramuscular), By Type(Norditropin, Genotropin) - Industry Forecast 2024-2031


Report ID: SQMIG35A2816 | Region: Global | Published Date: April, 2024
Pages: 219 | Tables: 95 | Figures: 76

Global Growth Hormone Deficiency Market Insights

Global Growth Hormone Deficiency Market size was valued at USD 3.47 billion in 2022 and is poised to grow from USD 3.70 billion in 2023 to USD 6.12 billion by 2031, growing at a CAGR of 6.50% in the forecast period (2024-2031).

The escalating prevalence of growth hormone deficiency (GHD), attributed to various factors such as brain injuries, genetic disorders, congenital conditions, and certain medical treatments, has spurred a heightened demand for growth hormone therapies. According to the National Center for Biotechnology Information (NCBI), pediatric growth hormone deficiency is identified in approximately 1 in every 3,500–4,000 children in the United Kingdom. This growing incidence has propelled the expansion of the industry, with increased research and development activities playing a pivotal role. Notably, in February 2022, a significant milestone was achieved as Pfizer and OPKO secured marketing authorization from the European Union for their Once-Weekly NGENLA™ (somatrogon) Injection.

Market snapshot - 2024-2031

Global Market Size

USD 3.47 billion

Largest Segment

Subcutaneous

Fastest Growth

Subcutaneous

Growth Rate

6.50% CAGR

Global Growth Hormone Deficiency Market ($ Bn)
Country Share for North america Region (%)
Global Growth Hormone Deficiency Market By Route of Administration ($ Bn)
Global Growth Hormone Deficiency Market By Route of Administration (%)

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Global Growth Hormone Deficiency Market Segmental Analysis

The Growth Hormone Deficiency market segmentation, based on application, includes pediatric growth hormone deficiency, idiopathic short stature, small for gestational age, turner syndrome, adult growth hormone deficiency, and prader willi syndrome. The market segmentation of Growth Hormone Deficiency, based on route of administration, includes subcutaneous, intramuscular, and intravenous. The market segments of Growth Hormone Deficiency, based on brand, includes norditropin, genotropin, humatrope, saizen, and omnitrope. Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Analysis by Distribution Channel

The online pharmacy segment plays a crucial role in the growth hormone deficiency market by serving as a convenient and accessible platform for the distribution of growth hormone therapies. With the increasing prevalence of growth hormone deficiency and the subsequent rise in demand for related treatments, online pharmacies offer a streamlined and user-friendly channel for patients to procure medications.

The hospital pharmacies segment asserted its dominance in the market in 2022, a phenomenon largely attributed to the growing awareness of growth hormone (GH) insufficiency in humans and the corresponding surge in hospital visits for diagnosis and treatment. The heightened awareness among individuals regarding the implications of GH deficiency has led to increased medical consultations, contributing to a notable uptick in hospital visits. As more people seek medical intervention for the management of GH insufficiency, hospital pharmacies have become pivotal hubs for the dispensing of growth hormone therapies.

Analysis by Route of Administration

The transdermal segment emerged as a dominant force in the growth hormone deficiency market in 2022. This dominance can be attributed to the good quality of dermal application, where the hormone is efficiently penetrated into cells. This approach offers distinct benefits to patients. Transdermal delivery provides a convenient and effective method of delivering growth hormone, increasing patient compliance and overall clinical outcomes. The dominance of the subcutaneous tissue underscores the importance of optimizing well-tolerated treatment for individuals with growth hormone deficiency.

The online pharmacy segment plays an important role in the growth hormone deficiency market by serving as a convenient and accessible distribution channel for growth hormone therapies. With the increasing prevalence of growth hormone deficiencies and the subsequent rise in demand for related treatments, online pharmacies offer a convenient and user-friendly approach for patients to buy medicines. Thus digital this approach makes it easier for individuals to order prescription hormone therapy from their home, improving access and patient compliance.

Global Growth Hormone Deficiency Market By Route of Administration, 2022 (%)

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Global Growth Hormone Deficiency Market Regional Insights

By 2022, North America emerged as the leading country in the growth hormone therapy market, commanding a substantial 42.27% of the total revenue, This leadership position can be attributed to improved health awareness among the population , outstanding government programs and good reimbursement programs in the region With more money, organizations dedicated to increasing awareness and treatment in the region are expected to contribute significantly to expansion of the market reaffirming the important role of North America in the development of growth hormone therapies.

Asia-Pacific is poised for a very promising growth trajectory throughout the forecast period, driven by several key factors. The prevalence of rare genetic conditions and associated high burden of diseases, coupled with unmet medical needs, makes the region a key market for growth factor treatment. Demand for new therapies in Asia The Pacific enhances its growth potential. Notably, Asia-Pacific benefits from significant investments by key market players attracted to the growing pharmaceutical industry These inflows demonstrate the strategic importance of suppliers to the region and is expected to contribute significantly to the expansion and growth of all growth hormone therapies in Asia Pacific.

Global Growth Hormone Deficiency Market By Region, 2024-2031
  • Largest
  • Fastest

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Global Growth Hormone Deficiency Market Dynamics

Drivers

Rise in Concern about Passenger Safety

  • Human growth hormone (HGH), also referred to as somatotropin, plays a pivotal role in human development by facilitating cell growth, division, and regeneration. Insufficient synthesis of growth hormone (GH) by the pituitary gland leads to a deficiency of hGH in humans. The remedy for this deficiency involves the subcutaneous administration of recombinant human growth hormone. Genetic disorders such as Prader-Willi syndrome and Turner syndrome, characterized by delayed puberty and shorter stature, can also contribute to growth hormone insufficiency.

Restraints

High Cost of HGH Therapy

  • The costs associated with human growth hormone (HGH) therapy are a major barrier, limiting access to a number of patients and complicating healthcare systems A study published in a medical journal in 2022 highlighted the enormous financial burden faced by patients and health systems Attention has come to the need for flexibility and implementation of potential price changes. Ensuring widespread availability of HGH treatment requires addressing financial challenges associated with its high price.

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Global Growth Hormone Deficiency Market Competitive Landscape

The competitive environment of the global Growth Hormone Deficiency market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor.

Top Player’s Company Profiles

  • Pfizer (US)
  • Eli Lilly and Company (US)
  • Genentech (US)
  • Novo Nordisk (Denmark)
  • Merck & Co. (US)
  • Sandoz International (Switzerland)
  • Ferring Pharmaceuticals (Switzerland)
  • Ipsen (France)
  • Teva Pharmaceutical Industries (Israel)
  • GeneScience Pharmaceuticals (China)
  • LG Chem (South Korea)
  • Anhui Anke Biotechnology Group (China)
  • Biopartners (Switzerland)
  • Procter & Gamble (US)
  • Endo International (Ireland)
  • LG Life Sciences (South Korea)
  • Versartis (US)
  • Opko Health (US)
  • LG Electronics (South Korea)
  • Rani Therapeutics (US)

Recent Developments

  • In August 2023, Genexine's weekly growth hormone, eftansomatropin alfa, has equaled daily injections in a pivotal China trial, positioning it, along with partners I-Mab and Jumpcan, for approval filing next year and eventual medicine launch. The Phase 3 trial compared eftansomatropin alfa to Norditropin, demonstrating comparable height velocity in children with growth hormone deficiency, meeting primary endpoint. 
  • In June 2023, Pfizer Inc. and OPKO Health Inc. disclosed that the U.S. Food and Drug Administration (FDA) has approved NGENLA (somatrogon-ghla), a human growth hormone analog administered once weekly. This medication is indicated for treating pediatric patients aged three years and older experiencing growth failure due to insufficient secretion of natural growth hormone. NGENLA is anticipated to be accessible for prescribing in the United States starting August 2023.

Global Growth Hormone Deficiency Key Market Trends

  • The pharmaceutical industry is poised for tremendous growth due to rapid advancements in drug delivery. Pioneering innovations such as wearables, needleless devices and autoinjectors have been central, improving the high level of comfort and patient compliance with growth hormone therapy delivery Notably the rapid availability of long-acting drugs and implantable devices is feasible, allowing for longer delivery times and longer delivery of growth hormone to reduce dose frequency Not that these improvements provide not only improve clinical outcomes, but improve the overall patient experience, expanding the availability and efficacy of growth hormone therapies.

Global Growth Hormone Deficiency Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyzes the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research. The market is experiencing significant expansion, fueled by a combination of several key factors contributing to its growth trajectory. A major factor is the increasing knowledge of growth hormone and its widespread use to prevent hormonal imbalances. This increased awareness has triggered increased demand for hormone therapy. At the same time, major pharmaceutical and biopharmaceutical companies are actively engaged in large-scale R&D efforts. This effort means bringing new hormone therapies to market, with a focus on long-term efficacy and improved safety profile This commitment to innovation is the driving force of global growth of the market.

Report Metric Details
Market size value in 2022 USD 3.47 billion
Market size value in 2031 USD 6.12 billion
Growth Rate 6.50%
Base year 2023
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Application
    • Pediatric growth hormone deficiency, Idiopathic short stature, Small for gestational age, Turner syndrome, Adult growth hormone deficiency, and Prader willi syndrome
  • Route of Administration
    • Subcutaneous, Intramuscular, and Intravenous
  • Type
    • Norditropin, Genotropin, Humatrope, Saizen, and Omnitrope
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Pfizer (US)
  • Eli Lilly and Company (US)
  • Genentech (US)
  • Novo Nordisk (Denmark)
  • Merck & Co. (US)
  • Sandoz International (Switzerland)
  • Ferring Pharmaceuticals (Switzerland)
  • Ipsen (France)
  • Teva Pharmaceutical Industries (Israel)
  • GeneScience Pharmaceuticals (China)
  • LG Chem (South Korea)
  • Anhui Anke Biotechnology Group (China)
  • Biopartners (Switzerland)
  • Procter & Gamble (US)
  • Endo International (Ireland)
  • LG Life Sciences (South Korea)
  • Versartis (US)
  • Opko Health (US)
  • LG Electronics (South Korea)
  • Rani Therapeutics (US)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Global Growth Hormone Deficiency Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Global Growth Hormone Deficiency Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Global Growth Hormone Deficiency Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Growth Hormone Deficiency Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Growth Hormone Deficiency Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Global Growth Hormone Deficiency Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Global Growth Hormone Deficiency Market size was valued at USD 3.47 billion in 2022 and is poised to grow from USD 3.70 billion in 2023 to USD 6.12 billion by 2031, growing at a CAGR of 6.50% in the forecast period (2024-2031).

The competitive environment of the global Growth Hormone Deficiency market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. 'Pfizer (US)', 'Eli Lilly and Company (US)', 'Genentech (US)', 'Novo Nordisk (Denmark)', 'Merck & Co. (US)', 'Sandoz International (Switzerland)', 'Ferring Pharmaceuticals (Switzerland)', 'Ipsen (France)', 'Teva Pharmaceutical Industries (Israel)', 'GeneScience Pharmaceuticals (China)', 'LG Chem (South Korea)', 'Anhui Anke Biotechnology Group (China)', 'Biopartners (Switzerland)', 'Procter & Gamble (US)', 'Endo International (Ireland)', 'LG Life Sciences (South Korea)', 'Versartis (US)', 'Opko Health (US)', 'LG Electronics (South Korea)', 'Rani Therapeutics (US)'

Human growth hormone (HGH), also referred to as somatotropin, plays a pivotal role in human development by facilitating cell growth, division, and regeneration. Insufficient synthesis of growth hormone (GH) by the pituitary gland leads to a deficiency of hGH in humans. The remedy for this deficiency involves the subcutaneous administration of recombinant human growth hormone. Genetic disorders such as Prader-Willi syndrome and Turner syndrome, characterized by delayed puberty and shorter stature, can also contribute to growth hormone insufficiency.

The pharmaceutical industry is poised for tremendous growth due to rapid advancements in drug delivery. Pioneering innovations such as wearables, needleless devices and autoinjectors have been central, improving the high level of comfort and patient compliance with growth hormone therapy delivery Notably the rapid availability of long-acting drugs and implantable devices is feasible, allowing for longer delivery times and longer delivery of growth hormone to reduce dose frequency Not that these improvements provide not only improve clinical outcomes, but improve the overall patient experience, expanding the availability and efficacy of growth hormone therapies.

By 2022, North America emerged as the leading country in the growth hormone therapy market, commanding a substantial 42.27% of the total revenue, This leadership position can be attributed to improved health awareness among the population , outstanding government programs and good reimbursement programs in the region With more money, organizations dedicated to increasing awareness and treatment in the region are expected to contribute significantly to expansion of the market reaffirming the important role of North America in the development of growth hormone therapies.

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