USD 592.9 Million
Report ID:
SQMIG15E2730 |
Region:
Global |
Published Date: May, 2025
Pages:
195
|Tables:
94
|Figures:
71
Global Fibrin Sealants Market size was valued at USD 592.9 Million in 2023 poised to grow from USD 639.1 Million in 2024 to USD 1165.6 Million by 2032, growing at a CAGR of 7.8% in the forecast period (2025-2032).
The continuous rise in the number of surgical procedures worldwide is a significant driver of the global fibrin sealants market. This growth is primarily attributed to the aging global population, which is more susceptible to chronic illnesses requiring surgical intervention, such as cardiovascular diseases, orthopedic disorders, and cancer. With more frequent and complicated surgeries, the need for effective hemostatic agents increases. The choice goes to fibrin sealants for their efficacy in rapid generation of stable clots and facilitating tissue sealing, thereby reducing blood loss, operating time, and recovery period. Increasing clinical dependence is the direct impetus for increased market demand for such biological adhesives.
One of the key trend driving the global fibrin sealants sector is the advancement of biologic and recombinant DNA technologies. These innovations have led to the development of safer, more effective fibrin sealants with longer shelf lives and reduced immunogenic risks. Improved manufacturing techniques now allow for the creation of synthetic and pathogen-free sealants, minimizing the risk of disease transmission associated with human plasma-derived products. Additionally, new formulations with enhanced adhesion and faster polymerization times provide better surgical outcomes. As a result, these cutting-edge developments are expanding the clinical acceptance and application range of fibrin sealants in modern surgical practices.
How is AI Enhancing Surgical Planning and Intraoperative Precision in the Use of Fibrin Sealants?
Artificial intelligence (AI) is playing a growing role in the global fibrin sealants market, mainly through improvement in surgical planning and post-op care. Imaging technologies based on AI, such as convolutional neural networks, improve the accuracy of fibrin sealant deployment by determining optimal sites of tissue adhesion and minimizing intraoperative bleeding and bettering surgical results. After surgery, AI-based wound monitoring platforms such as Deepwound use smartphone photographs to identify complications like infection or fibrinous exudate and allow for interventions at the appropriate time, and also for more rapid healing. Additionally, AI facilitates research and development of next-generation fibrin sealants through analysis of massive datasets to reveal patterns and predict product performance, driving innovation and market expansion.
In August 2023, Grifols, an international healthcare company, announced that it will partner with Google Cloud to tap into artificial intelligence (AI) for speeding up therapeutic development. The partnership will use large-scale language models driven by AI to improve the drug development process, which could influence the fibrin sealants market by optimizing research and development.
Market snapshot - 2025-2032
Global Market Size
USD 592.9 Million
Largest Segment
Patch
Fastest Growth
Liquid
Growth Rate
7.8% CAGR
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The global fibrin sealants market is segmented based on dosage form, application, end user, and region. In terms of dosage form, the market is trifurcated into liquid, patch, and powder. Based on the application, the market is grouped into general surgery, cardiovascular surgery, wound management, orthopedic surgery, urological surgeries, ophthalmic surgeries, and others. Based on end user, the market is segmented into hospitals, ambulatory surgical centers, and clinics. Based on region, the market is segmented into North America, Europe, Asia-Pacific, Central & South America and the Middle East & Africa.
Based on global fibrin sealants market forecast, patch dosage forms are transforming the industry by introducing innovations such as absorbable, two-sided patches that provide quick hemostasis and improved adhesion of tissues. Such patches play a major role in minimally invasive procedures by offering controlled delivery and minimizing preparation time over liquid preparations. Their success is due to the ease of handling, storage at room temperature, and better performance in intricate operations like cardiovascular and neurosurgery.
Liquid fibrin sealants are poised to be the fastest-growing segment in the global fibrin sealants market due to their superior adaptability and rapid hemostatic action. Their liquid state enables accurate delivery in minimally invasive and complex procedures, e.g., cardiovascular and orthopedic surgeries, where conventional practices might be less effective. Breakthroughs in formulation technologies have improved their stability and adhesion characteristics, thus making them increasingly popular among surgeons.
General surgery remains the dominant application in the global fibrin sealants market, driven by its extensive use in procedures like gastrointestinal, hepatobiliary, and cardiothoracic surgeries. Fibrin sealants are preferred because they can rapidly induce hemostasis, reduce postoperative complications, and strengthen tissue adhesion, particularly for minimally invasive procedures. They are versatile and effective in treating a wide range of surgical interventions, which underpins their global use in general surgery, maintaining its market-dominating role.
Cardiovascular surgery is projected to be the fastest-growing application in the global fibrin sealants market due to the escalating prevalence of heart diseases, which account for approximately quarter of global deaths annually . Fibrin sealants are vital in these procedures for achieving rapid hemostasis, especially in patients on anticoagulants, and for sealing vascular grafts, thereby reducing postoperative complications.
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As per the global fibrin sealant market analysis, North America leads the industry with almost 50% market share. This is largely due to the advanced health care infrastructure, high volume of surgeries, and high percentage of an aging population. The occurrence of key market players such as Baxter, Grifols, and Johnson & Johnson also powers market expansion. Moreover, higher expenditure on health care and growing prevalence of chronic disorders, including cardiovascular diseases, continue to drive sales of fibrin sealants in surgical procedures.
The United States is the market leader in North America's fibrin sealants market, prompted by a strong healthcare infrastructure, the high volume of surgeries, and a high incidence of chronic conditions such as cardiovascular diseases. Having key players like Baxter, Grifols, and Johnson & Johnson also boosts the market. Rising healthcare spending and a growing geriatric population also add to the sustained demand for fibrin sealants in surgeries in the country.
Canada's fibrin sealants market is expanding due to a well-established healthcare system, rising surgical procedures, and an aging population. The country's robust healthcare infrastructure and growing incidence of chronic diseases such as cardiovascular diseases and cancer fuel the demand for efficient hemostatic agents. Additionally, the penetration of sophisticated surgical practices and presence of major market players fuel the growth of the Canadian fibrin sealants market.
Europe contributes a major proportion to the global fibrin sealants market due to developed healthcare infrastructure, superior surgical volumes, and an escalating number of chronic disease patients. Leading contributors are nations such as Germany, the UK, and France, with Germany accounting for more than 100,000 cardiovascular surgeries every year. The popularity of minimally invasive surgical procedures and rigorous regulatory requirements further enhance the demand for fibrin sealants in the region. Also, growing healthcare investments and patient awareness are anticipated to continue to drive market growth.
Germany leads the Europe’s fibrin sealants market, driven by its advanced healthcare infrastructure and high surgical volumes. The country reports over 100,000 cardiovascular surgeries annually, emphasizing the extensive use of fibrin sealants in complex procedures. The demand is also driven by the population aging and rising incidence of chronic diseases, making Germany a leading player in the European market.
France's market for fibrin sealants is driven by a strong health system and high rate of surgical procedures. The country's emphasis on advanced medical technologies and patient care drives the adoption of fibrin sealants. With a growing elderly population and rising chronic disease rates, France continues to be a significant contributor to the European market.
Italy's fibrin sealants market is expanding due to a combination of factors, including a well-established healthcare system and a rising number of surgical interventions. The nation's emphasis on medical innovation and the use of new surgical methods are the reasons behind the increasing demand for fibrin sealants. The Italian market is on the verge of further expansion as healthcare demands change.
Asia-Pacific is witnessing high growth in the global fibrin sealants market with enhanced healthcare infrastructure, increasing surgical procedures, and growing patient awareness. China, Japan, and India are important drivers among countries, with a fast-growing aging population and an increase in chronic diseases being the major demand drivers. Increased use of minimally invasive surgeries by the region increases market growth, positioning itself as a strategic focal point for fibrin sealant producers worldwide.
Japan contributes significantly to the Asia Pacific’s fibrin sealants market, driven by its aging population and advanced healthcare infrastructure. Demand for fibrin sealants is rising, particularly for cardiovascular and orthopedic surgery. Japan's focus on minimally invasive surgeries further drives market growth as medical practitioners seek to have effective hemostatic agents for intricate procedures, making the country a prime market in the Asia-Pacific region.
South Korea's role in the Asia Pacific’s fibrin sealants market is significant, with increasing demand for minimally invasive surgical techniques. The high volumes of surgeries in South Korea, especially cardiovascular and trauma surgery, are stimulating demand for fibrin sealants. South Korea's established healthcare infrastructure and improvements in medical technologies further continue to provide a positive backdrop for the market's growth, making it a prominent in the regional outlook.
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The global fibrin sealants market outlook is very competitive, with numerous global players competing for market share. The players are Johnson & Johnson, Baxter International, and CSL Behring. The players aim to broaden their product lines, invest in research and development, and develop strategic alliances. For instance, CSL Behring's strategy is to drive product innovation and execute global market penetration, while Johnson & Johnson's strategy is to advance its medical device portfolio and global distribution networks.
The startup environment of the global fibrin sealants market is dominated by new companies emphasizing innovation and innovative hemostatic solution approaches. The startups are leading the way in fibrin sealant product developments, enhancing patient outcomes, minimizing complications, and providing affordable alternatives to conventional procedures. Backed by significant R&D spending, they are becoming major players in the expanding market, particularly in minimally invasive procedures.
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per SkyQuest analysis, the global fibrin sealants industry is enjoying strong growth driven by the rising number of surgical procedures prompted by aging populations and increasing incidence of chronic diseases. Advances in biologic and recombinant DNA technologies have improved the safety, effectiveness, and shelf life of fibrin sealants, promoting greater usage.
The role of AI in intraoperative precision and postoperative follow-up further facilitates this market to grow. Led by major industry players developing improved products and growth markets such as North America and Europe, the fibrin sealants market looks to continue a successful run. The increasing number of minimally invasive procedures along with the rise in autologous fibrin sealants play a part as well in increasing market dynamism and long-term growth.
Report Metric | Details |
---|---|
Market size value in 2023 | USD 592.9 Million |
Market size value in 2032 | USD 1165.6 Million |
Growth Rate | 7.8% |
Base year | 2024 |
Forecast period | 2025-2032 |
Forecast Unit (Value) | USD Million |
Segments covered |
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Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
Companies covered |
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Table Of Content
Executive Summary
Market overview
Parent Market Analysis
Market overview
Market size
KEY MARKET INSIGHTS
COVID IMPACT
MARKET DYNAMICS & OUTLOOK
Market Size by Region
KEY COMPANY PROFILES
Methodology
For the Fibrin Sealants Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Fibrin Sealants Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
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Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Fibrin Sealants Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
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Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
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Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
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Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
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Global Fibrin Sealants Market size was valued at USD 592.9 Million in 2023 poised to grow from USD 639.1 Million in 2024 to USD 1165.6 Million by 2032, growing at a CAGR of 7.8% in the forecast period (2025-2032).
The global fibrin sealants market outlook is very competitive, with numerous global players competing for market share. The players are Johnson & Johnson, Baxter International, and CSL Behring. The players aim to broaden their product lines, invest in research and development, and develop strategic alliances. For instance, CSL Behring's strategy is to drive product innovation and execute global market penetration, while Johnson & Johnson's strategy is to advance its medical device portfolio and global distribution networks. 'Johnson & Johnson (USA)', 'Baxter International (USA)', 'CSL Behring (Australia)', 'Pfizer (USA)', 'Lantheus Medical Imaging (USA)', 'Fresenius Kabi (Germany)', 'Medtronic (Ireland)', 'Grifols (Spain)', 'AbbVie (USA)', 'CryoLife (USA)', 'Haemostatix (UK)', 'Tissuetech (USA)', 'Octapharma (Switzerland)', 'Laboratoires Théa (France)', 'B. Braun (Germany)'
The growing number of surgical procedures worldwide is a significant driver for the global fibrin sealants market growth. With an upsurge in the incidence of chronic ailments including cardiovascular diseases, cancer, and orthopedic disorders, the requirement for efficient hemostatic tools such as fibrin sealants in surgical procedures augments, driving market growth.
Growing Demand for Minimally Invasive Surgeries: The growing trend towards minimally invasive procedures is driving the demand for fibrin sealants. The sealants have the ability to offer quicker recovery, less bleeding, and better surgical results. Their use is being widely seen in applications such as cardiovascular and orthopedic procedures, where accuracy and rapid patient recovery are essential.
Why does a High Volume of Surgeries in North America Boost Fibrin Sealant Demand?
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