USD 5.95 Billion
Digital PCR Market Size, Share, Growth Analysis, By Technology(droplet digital PCR (ddPCR) and chip-based digital PCR (cdPCR)), By Product Type(instruments, reagents and consumables), By Application(clinical diagnostics, research) - Industry Forecast 2024-2031
Report ID:
SQMIG35G2206 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|
Tables:
89 |
Figures:
76
Digital PCR Market Insights
Global Digital PCR Market size was valued at USD 5.95 Billion in 2022 and is poised to grow from USD 6.49 Billion in 2023 to USD 13.07 Billion by 2031, at a CAGR of 9.14% during the forecast period (2024-2031).
The Global Digital PCR (Polymerase Chain Reaction) Market is a rapidly growing market driven by the increasing demand for precise and sensitive nucleic acid quantification and analysis. Digital PCR offers unparalleled accuracy and sensitivity, making it an essential tool in genetic testing, disease diagnosis, and research applications. The market's purpose is to provide advanced molecular diagnostic solutions that enable healthcare providers, clinical laboratories, and researchers to obtain precise and reliable results for better patient care and scientific advancements. The market is primarily driven by factors such as the rising prevalence of genetic disorders and infectious diseases, growing demand for personalized medicine, and advancements in genomic research. However, the market also faces restraints such as the high cost of digital PCR instruments and limited awareness among end-users. Key trends in the market include the integration of digital PCR with next-generation sequencing technologies and the development of multiplex digital PCR assays for simultaneous detection of multiple targets. Despite the challenges, the market presents significant opportunities for expansion, fueled by the increasing adoption of digital PCR in emerging economies, expanding applications in oncology and infectious disease diagnostics, and the introduction of innovative products with enhanced features
Market snapshot - 2024-2031
Global Market Size
Largest Segment
droplet digital PCR (ddPCR)
Fastest Growth
droplet digital PCR (ddPCR)
Growth Rate
9.14% CAGR
Global Digital PCR Market ($ Bn)
Country Share for North america Region (%)
Global Digital PCR Market By Technology ($ Bn)
Global Digital PCR Market By Technology (%)
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Digital PCR Market Segmental Analysis
Global Digital PCR Market is segmented on the basis of technology, product type, application, and region. By technology, the market is segmented into droplet digital PCR (ddPCR) and chip-based digital PCR (cdPCR). By product type, the market is segmented into instruments, reagents and consumables, and software and services. By application, the market is segmented into clinical diagnostics, research, forensics, and environmental monitoring. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Digital PCR Market Analysis By Technology
The largest segment in the global dPCR market is droplet digital PCR (ddPCR). ddPCR is a cutting-edge technology that offers exceptional accuracy and sensitivity in quantifying nucleic acids. It works by partitioning a sample into thousands of droplets, each containing a single molecule, and amplifying the target DNA or RNA within each droplet. This technique enables researchers and clinicians to detect and analyze rare genetic variations and mutations with utmost precision. The popularity of ddPCR can be attributed to its numerous advantages. With ddPCR, researchers can achieve absolute quantification of target molecules without relying on calibration curves, making it highly reliable and reproducible. Additionally, ddPCR provides higher sensitivity compared to other PCR methods, enabling the detection of extremely low abundance targets, such as circulating tumor DNA or rare viral sequences. These unique capabilities have made ddPCR an invaluable tool in areas such as cancer research, liquid biopsy, and infectious disease diagnostics.
In terms of growth, the fastest-growing segment in the global dPCR market is chip-based digital PCR (cdPCR). This innovative technology has gained significant attention due to its potential for high-throughput analysis and streamlined workflow. cdPCR utilizes microfluidic chips embedded with thousands of reaction chambers, allowing simultaneous amplification and detection of multiple DNA or RNA targets. The rapid growth of cdPCR is driven by its ability to deliver precise and scalable digital PCR results. By leveraging the power of miniaturization, cdPCR enables researchers to perform numerous reactions in parallel, significantly reducing the turnaround time for experiments. This high-throughput capability is especially beneficial in clinical settings where large-scale sample processing is required, such as in population screening or genetic testing for hereditary diseases. Moreover, the chip-based approach offers enhanced reproducibility and robustness, making it an appealing choice for researchers and diagnostic laboratories. Its automated workflow reduces human error and simplifies data analysis, facilitating the integration of cdPCR into routine laboratory practices.
Digital PCR Market Analysis By Application
The largest segment in the digital PCR market is clinical diagnostics. Clinical diagnostics holds a dominant position due to its vital role in revolutionizing disease detection and monitoring. With its unparalleled sensitivity and precision, digital PCR has emerged as a game-changer in the field of healthcare. It offers accurate and reliable detection of genetic mutations, infectious diseases, and cancer biomarkers, facilitating early diagnosis and personalized treatment strategies. The clinical diagnostics segment is witnessing exponential growth, driven by the increasing demand for precise and rapid disease diagnosis worldwide. As healthcare providers and researchers recognize the immense potential of digital PCR in improving patient outcomes, the adoption of this technology is skyrocketing.
The fastest-growing segment in the digital PCR market is research. Researchers across various disciplines are leveraging the power of digital PCR to gain deeper insights into genetic variations, gene expression, and the intricate mechanisms underlying diseases. Digital PCR's ability to detect and quantify rare genetic events with exceptional accuracy has made it an invaluable tool in areas such as oncology research, infectious disease studies, and pharmacogenomics. The research segment is experiencing rapid expansion due to the escalating demand for advanced molecular techniques that offer precise and reliable data. The integration of digital PCR in research workflows has significantly enhanced experimental outcomes, leading to groundbreaking discoveries and advancements in the field.
Global Digital PCR Market By Technology, 2023 (%)
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Digital PCR Market Regional Insights
North America, the reigning champion in the digital PCR market, continues to dominate with its advanced healthcare infrastructure, robust R&D investments, and highly developed biotechnology industry. The region's extensive adoption of digital PCR technology across multiple applications, including cancer research, infectious diseases, and personalized medicine, has propelled its market position. The presence of key market players and renowned research institutions further strengthens North America's dominance in the digital PCR landscape.
On the other hand, the Asia Pacific region is emerging as the fastest-growing market for digital PCR. The region's massive population, rising healthcare expenditure, and increasing awareness about the importance of early disease detection are driving the demand for advanced molecular diagnostic technologies. Furthermore, countries like China and India are witnessing significant investments in genomics research and biotechnology, fostering the adoption of digital PCR. With the expanding base of pharmaceutical and biotech companies in the region, the Asia Pacific market for digital PCR is experiencing unprecedented growth, poised to capture a substantial market share.
Global Digital PCR Market By Region, 2024-2031
- Largest
- Fastest
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Digital PCR Market Dynamics
Digital PCR Market Drivers
Technological advancements in dPCR
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Technological advancements in digital polymerase chain reaction (dPCR) are poised to drive market growth significantly. This represents an evolution of traditional PCR technology, offering direct quantification and clonal amplification of nucleic acids. The burgeoning demand for innovative devices, coupled with increased research and development activities, has ushered in various PCR technologies offering substantial advantages.
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Key market players are introducing innovative devices based on techniques like droplet, chip-based, beam, and crystal reactions, which are expected to be instrumental in propelling market expansion. For Instance, In November 2022, Shenzhen New Industries Biomedical Engineering Co., Ltd. unveiled a new addition to the Snibe Molecular portfolio, the Molecision S6 digital PCR system, at MEDICA 2022.
- The Molecision S6 stands as an automated, integrated digital PCR system, providing a comprehensive platform solution for research and in vitro diagnostics. Such pioneering technological advancements are anticipated to drive market growth during the forecast period from 2023 to 2030.
Numerous advantages of digital polymerase chain reaction (dPCR) over real-time polymerase chain reaction
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Digital PCR offers numerous advantages over real-time Polymerase Chain Reaction (PCR), thereby bolstering its global market appeal. Digital techniques excel in delivering an absolute measure of target nucleic acid molecules compared to the relative measurements obtained from real-time devices. This absolute DNA quantification enhances reproducibility, sensitivity, and precision, allowing researchers to quantify minor differences and measure minor variants with exceptional accuracy.
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Furthermore, while real-time PCR has widespread applications, it is not the preferred technique for detecting certain parasitic infectious diseases like malaria and COVID-19. This is due to the presence of multiple types of genomes within the virus and the extremely low template concentration in the samples. Digital droplet devices effectively address these challenges and yield precise results, facilitating better comparability of outcomes across different research groups. For Instances, in March 2022, as highlighted in a Clinical Microbiology Review article regarding the detection and diagnosis of SARS-CoV-2, digital technology-based tests have gained prominence over real-time polymerase chain reaction due to the multitude of benefits associated with them.
Digital PCR Market Restraints
High Instrument and Reagent Costs
- The adoption of digital PCR technology can be hindered by the high upfront costs associated with the purchase of instruments and reagents. Digital PCR systems require specialized equipment and consumables, which can be expensive for research laboratories or smaller healthcare facilities. The high costs may limit the accessibility of digital PCR technology, particularly in resource-limited settings or for researchers with budget constraints.
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Digital PCR Market Competitive Landscape
The Global Digital PCR Market is highly competitive and characterized by the presence of several prominent players. These companies are focused on strategies such as mergers and acquisitions, partnerships, collaborations, and product launches to strengthen their market position. Some of the key players in the market are investing significantly in research and development activities to introduce technologically advanced digital PCR platforms and expand their product portfolios. They are also adopting various marketing strategies to enhance their brand visibility and reach a wider customer base.
Digital PCR Market Top Player’s Company Profile
- Thermo Fisher Scientific (US)
- Bio-Rad Laboratories (US)
- QIAGEN (Germany)
- F. Hoffmann-La Roche Ltd (Switzerland)
- Fluidigm Corporation (US)
- Merck KGaA (Germany)
- Agilent Technologies (US)
- BioMérieux SA (France)
- Takara Bio Inc. (Japan)
- Danaher Corporation (US)
- JN Medsys (Singapore)
- RainDance Technologies (US)
- Formulatrix, Inc. (US)
- Stilla Technologies (France)
- Becton, Dickinson and Company (US)
- Analytik Jena AG (Germany)
- Douglas Scientific (US)
- Sysmex Corporation (Japan)
- GenMark Diagnostics, Inc. (US)
- Quantabio (US)
Digital PCR Market Recent Developments
- In July 2021, StillaTechnologies unveiled its sic Color Crystal Digital PCR (dPCR) access program, an exciting initiative that grants early access to its advanced digital polymerase chain reaction (PCR) system featuring six fluorescent channels. This access program opens up new possibilities for the industry, enabling researchers and professionals to harness the full potential of multiplex digital PCR assays. With the ability to detect and analyze multiple targets simultaneously, StillaTechnologies' dPCR system equipped with six fluorescent channels offers enhanced flexibility and efficiency in genetic analysis.
Digital PCR Key Market Trends
- Integration of Digital PCR with Next-Generation Sequencing (NGS): Digital PCR and NGS technologies are complementary and can be integrated to provide comprehensive genomic analysis. The combination of digital PCR's absolute quantification capabilities with NGS's ability to provide sequencing data allows researchers to obtain both qualitative and quantitative information. This integration facilitates the identification of rare genetic variants, validation of NGS results, and analysis of complex genomic alterations in diseases.
Digital PCR Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
According to our analyses, The Global Digital PCR (Polymerase Chain Reaction) Market has experienced significant growth in recent years, according to market research analysts. Digital PCR is a precise and sensitive method for quantifying and detecting nucleic acids, making it widely used in various applications such as clinical diagnostics, research, and pharmaceutical development. The increasing demand for advanced molecular diagnostics, rising prevalence of infectious diseases, and growing adoption of personalized medicine are driving the market's expansion. Additionally, the development of technologically advanced digital PCR platforms, coupled with the availability of cost-effective solutions, is further fueling market growth. Moreover, collaborations and partnerships between key players in the market and academic institutions are facilitating research and development activities, fostering market expansion. However, factors like high instrument costs and technical complexities associated with digital PCR may hinder market growth to some extent. Overall, the global digital PCR market is poised for continued growth as it plays a crucial role in precision medicine, genetic testing, and biomarker research, offering promising opportunities for market players.
| Report Metric | Details |
|---|---|
| Market size value in 2023 | USD 5.95 Billion |
| Market size value in 2031 | USD 13.07 Billion |
| Growth Rate | 9.14% |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Digital PCR Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Digital PCR Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Digital PCR Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Digital PCR Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Digital PCR Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Digital PCR Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
Digital PCR Market Report Snapshots
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