Global Aptamers Market

Global Aptamers Market Size, Share, Growth Analysis, By Type(Nucleic Acid and Peptide), By Application(Diagnostics, Therapeutics) - Industry Forecast 2023-2030


Report ID: SQMIG35E2038 | Region: Global | Published Date: February, 2024 | Pages: 157 | Tables: 62 | Figures: 77

Global Aptamers Market Insights

Aptamers Market size was valued at USD 1.58 billion in 2021 and is poised to grow from 1.99 USD billion in 2022 to USD 9.84 billion by 2030, at a CAGR of 25.69% during the forecast period (2023-2030).

Many researchers are interested in aptamers because of their competitive advantages in recent developments in the production, purification, and drug delivery for killing target cells. Small molecular size, low immunogenicity, low manufacturing costs, and less side effects compared to antibodies are a few of the benefits; these factors may encourage the development of innovative aptamers, leading to market expansion.

Due to several genetic variations, there are presently no extremely effective therapies for infections, despite extensive attempts. The SELEX technology-based diagnostic kits and assays have the capacity to produce high-affinity neutralizers. As a result, it is anticipated that the release of diagnostic kits on the market will spur market expansion. Aptamer is a second-generation diagnostic kit for healthcare that was created utilising DNA aptamer-based technology.

It is inexpensive, chemically synthesised, and a growing diagnostic kit. Soma Logic stated in March 2022 that it had begun employing the SomaScan Assay to analyse 210 million protein measurements from 30,000 samples for the European Prospective Investigation into Cancer and Nutrition (EPIC) research. Through a deeper understanding of the disease, researchers will be better able to forecast cancer, which will help the market flourish by meeting the growing demand.

Due to their tiny size, high specificity, selectivity, and efficacy, diagnostic solutions based on aptamers are the preferred option among diagnostic and pathology labs for the diagnosis of disease at the cellular level. Around 27.5 million individuals are anticipated to receive a cancer diagnosis by the year 2040, according to predictions from Cancer Research UK.

US Aptamers Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2023-2030

Global Market Size

USD 1.58 billion

Largest Segment

Nucleic Acid

Fastest Growth

Nucleic Acid

Growth Rate

25.69% CAGR

Global Aptamers Market ($ Bn)
Country Share for North America Region (%)
Global Aptamers Market Size By Type ($ Bn)
Global Aptamers Market Size By Type (%)

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Global Aptamers Market Segmental Analysis

Global Aptamers Market is segmented on the basis of type, application and region. By type, the market is segmented into nucleic acid and peptide. By application, market is segmented into diagnostics, therapeutics, research & development, others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Analysis by Type

The sector for nucleic acids had the most market share in 2022 (78.19%), and it is anticipated to increase at the fastest rate during the forecast period. The mechanism of action of nucleic acid aptamers for the treatment of various illnesses, such as age-related muscle degeneration (AMD), is now being studied by a large number of firms. For instance, the U.S. Food and Drug Administration (FDA) approved IVERIC BIO (previously Ophthotech Corporation) in writing under Special Protocol Assessment (SPA) for the design of the GATHER2 phase 3 clinical trial of Zimura for the treatment of individuals with GA secondary to AMD. This approval is anticipated to accelerate segment expansion.

Due to its wide range of therapeutic and diagnostic use, the peptide aptamer market is anticipated to expand at a lucrative CAGR of 22.77% between 2023 and 2030. As an illustration, researchers from the Engineering Centre for Microtechnology and Diagnostics created a new biosensor for multiparametric express testing in the preclinical diagnosis of cardiovascular disease. For this testing, the peptide aptamer marker system and molecular recognition have been used to construct next-generation biochips. Peptide aptamers have been created for this purpose utilizing information from Protein 3D and data from Data Bank. So, the availability of such goods could increase the use of peptide aptamers.

Analysis by Application

In 2022, the market share occupied by the research and development sector was 31.38%. The increase in research activities in this area and the rising demand for aptamers have created a market for them in the field of research and development, which is what is responsible for the segment's rise. Key actors have engaged in a variety of strategic efforts, such as joint ventures, partnerships, and agreements for the research and development of innovative aptamer-based diagnostic and therapeutic products.

The therapeutics market is predicted to grow at a lucrative rate between 2023 and 2030, with a CAGR of 26.08%, thanks to the ability to rationally design antidotes (which is difficult with antibodies). It is also regarded as the superior option compared to protein therapeutics in terms of synthetic accessibility, size, and medicinal chemistry modification. All of these facts work together to support the therapeutics market segment's efforts to establish a solid presence in the coming years. The segment expansion, however, can be constrained by nuclease resistance, a significant concern connected to therapeutic aptamers.

Global Aptamers Market Size By Type (%), 2021 (%)

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Global Aptamers Market Regional Insights

With a market share of 44.48% in 2022, North America region led the aptamers market. The rising incidence of chronic diseases, the region's robust healthcare system, and the growing interest of research labs in the field of aptamers are some of the main drivers of the area's supremacy. Also in April 2022, Noxxon Pharma made the announcement that it would disclose top line results for its NOX-A12 GLORIA study in brain cancer at the annual meeting of the American Society of Clinical Oncology.

The market for aptamers in Asia Pacific is anticipated to expand at the quickest rate, with a CAGR of 26.18%. The region's growth is attributable to the acceptance of new aptamer-based products in the area. For instance, Achiko AG signed a contract with the Pengurus Wilayah Nahdlatul Ulama DKI, the largest Islamic organization in the world with headquarters in Jakarta, for the marketing and distribution of Aptamer, a COVID-19 diagnostic kit based on aptamers. In Indonesia, this organization has 90 million registered members.

Global Aptamers Market Size By Geography, 2023-2030
  • Largest
  • Fastest

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Global Aptamers Market Dynamics

Drivers

Increasing Demand for Personalized Medicine

  • Aptamers play a crucial role in personalized medicine as they can specifically bind to target molecules, including proteins, peptides, and small molecules. The growing emphasis on targeted therapies and precision medicine has led to increased demand for aptamers as they offer advantages such as high specificity, low immunogenicity, and customizable properties. Aptamers enable precise molecular recognition, facilitating the development of personalized treatment strategies.

Advantages over Traditional Antibodies

  • Aptamers offer several advantages over traditional antibodies, which have propelled their adoption in various applications. Aptamers can be easily synthesized and modified, allowing for cost-effective production and customization for specific targets. They exhibit high binding affinity and specificity, comparable to antibodies, while being smaller in size and less immunogenic. These characteristics make aptamers attractive for diagnostic, therapeutic, and research purposes.

Restraints

Intellectual Property Issues

  • Intellectual property (IP) challenges can hinder the growth of the aptamers market. Patent rights and licensing agreements for aptamers and related technologies can limit the commercialization potential for certain applications or specific targets. The IP landscape surrounding aptamer-based technologies can be complex, leading to legal uncertainties and potential barriers for market players.

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Global Aptamers Market Competitive Landscape

To increase their market share, major players are using tactics including product modification, new product approval, mergers and acquisitions, and geographical growth. These methods are all aimed at improving their current products. Applications of aptamers in therapeutics may find new growth opportunities as a result of such activities.

Top Player’s Company Profiles

  • SomaLogic, Inc. (United States)
  • Vivonics, Inc. (United States)
  • Aptamer Sciences, Inc. (United States)
  • TriLink BioTechnologies, LLC (United States)
  • AMS Biotechnology Europe Ltd. (United Kingdom)
  • Aptamer Group Ltd. (United Kingdom)
  • NOXXON Pharma AG (Germany)
  • AM Biotechnologies, LLC (United States)
  • Aptus Biotech S.L. (Spain)
  • Aptamer Group (United Kingdom)
  • Ophthotech Corporation (United States)
  • Vivonics, Inc. (United States)
  • ATDBio Ltd. (United Kingdom)
  • Base Pair Biotechnologies, Inc. (United States)
  • Am Biotechnologies, LLC (United States)
  • Aptamer Sciences, Inc. (United States)
  • Orla Protein Technologies Ltd. (United Kingdom)
  • Archemix Corp. (United States)
  • AptaMatrix (United States)

Recent Developments

  • In May 2023, Aptamer Sciences announced that it has received FDA clearance for its AptaDetect™ assay for the detection of human papillomavirus (HPV). The assay is a rapid, point-of-care test that can be used to detect HPV in cervical swabs.
  • In April 2023, AptaTarget announced that it has entered into a collaboration with AstraZeneca to develop aptamers for the treatment of cancer. The collaboration will focus on the development of aptamers that can target and kill cancer cells.
  • In March 2023, QIAGEN announced that it has acquired Epigentek, a company that develops aptamers for use in diagnostics and therapeutics. The acquisition will strengthen QIAGEN's position in the aptamer market and will help the company to expand its product portfolio.

Global Aptamers Key Market Trends

  • Focus on SELEX Optimization and Automation : SELEX (Systematic Evolution of Ligands by Exponential Enrichment) is the primary method for aptamer selection. There is a growing focus on optimizing and automating the SELEX process to enhance efficiency, reduce costs, and improve aptamer quality. Advances in high-throughput screening, microfluidics, and robotics are being employed to streamline the aptamer development process, making it more accessible and scalable.

Global Aptamers Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.

According to our analyses, the global aptamers market is poised for significant growth and holds immense potential for various applications in diagnostics, therapeutics, and research. The global aptamers market has been experiencing steady growth in recent years. The market size is expected to reach billions of dollars by the end of the forecast period. Aptamers have emerged as valuable tools in diagnostic applications. They offer advantages such as high specificity, sensitivity, and rapid binding kinetics, making them ideal for detecting disease biomarkers, pathogens, and other analytes. Aptamer-based diagnostic platforms are gaining popularity due to their ability to provide accurate and rapid test results. The aptamers market is witnessing continuous technological advancements. Researchers are exploring innovative aptamer selection techniques, modifications, and delivery systems to enhance their properties and broaden their application scope. Advances in high-throughput screening, automation, and nanotechnology are driving the development of more efficient and specific aptamers.

Report Metric Details
Market size value in 2021 USD 1.58 billion
Market size value in 2030 USD 9.84 billion
Growth Rate 25.69%
Base year 2021
Forecast period 2023-2030
Forecast Unit (Value) USD Billion
Segments covered
  • Type
    • Nucleic Acid and Peptide
  • Application
    • Diagnostics, Therapeutics, Research & Development, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • SomaLogic, Inc. (United States)
  • Vivonics, Inc. (United States)
  • Aptamer Sciences, Inc. (United States)
  • TriLink BioTechnologies, LLC (United States)
  • AMS Biotechnology Europe Ltd. (United Kingdom)
  • Aptamer Group Ltd. (United Kingdom)
  • NOXXON Pharma AG (Germany)
  • AM Biotechnologies, LLC (United States)
  • Aptus Biotech S.L. (Spain)
  • Aptamer Group (United Kingdom)
  • Ophthotech Corporation (United States)
  • Vivonics, Inc. (United States)
  • ATDBio Ltd. (United Kingdom)
  • Base Pair Biotechnologies, Inc. (United States)
  • Am Biotechnologies, LLC (United States)
  • Aptamer Sciences, Inc. (United States)
  • Orla Protein Technologies Ltd. (United Kingdom)
  • Archemix Corp. (United States)
  • AptaMatrix (United States)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Global Aptamers Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Global Aptamers Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Global Aptamers Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Aptamers Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Global Aptamers Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Global Aptamers Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQ's

Aptamers Market size was valued at USD 1.58 billion in 2021 and is poised to grow from 1.99 USD billion in 2022 to USD 9.84 billion by 2030, at a CAGR of 25.69% during the forecast period (2023-2030).

To increase their market share, major players are using tactics including product modification, new product approval, mergers and acquisitions, and geographical growth. These methods are all aimed at improving their current products. Applications of aptamers in therapeutics may find new growth opportunities as a result of such activities. 'NeoVentures Biotechnology Inc. (United States)', 'Base Pair Biotechnologies, Inc. (United States)', 'Aptagen, LLC (United States)', 'SomaLogic, Inc. (United States)', 'Vivonics, Inc. (United States)', 'Aptamer Sciences, Inc. (United States)', 'TriLink BioTechnologies, LLC (United States)', 'AMS Biotechnology Europe Ltd. (United Kingdom)', 'Aptamer Group Ltd. (United Kingdom)', 'NOXXON Pharma AG (Germany)', 'AM Biotechnologies, LLC (United States)', 'Aptus Biotech S.L. (Spain)', 'Aptamer Group (United Kingdom)', 'Ophthotech Corporation (United States)', 'Vivonics, Inc. (United States)', 'ATDBio Ltd. (United Kingdom)', 'Base Pair Biotechnologies, Inc. (United States)', 'Am Biotechnologies, LLC (United States)', 'Aptamer Sciences, Inc. (United States)', 'Orla Protein Technologies Ltd. (United Kingdom)', 'Archemix Corp. (United States)', 'AptaMatrix (United States)'

Aptamers play a crucial role in personalized medicine as they can specifically bind to target molecules, including proteins, peptides, and small molecules. The growing emphasis on targeted therapies and precision medicine has led to increased demand for aptamers as they offer advantages such as high specificity, low immunogenicity, and customizable properties. Aptamers enable precise molecular recognition, facilitating the development of personalized treatment strategies.

Focus on SELEX Optimization and Automation : SELEX (Systematic Evolution of Ligands by Exponential Enrichment) is the primary method for aptamer selection. There is a growing focus on optimizing and automating the SELEX process to enhance efficiency, reduce costs, and improve aptamer quality. Advances in high-throughput screening, microfluidics, and robotics are being employed to streamline the aptamer development process, making it more accessible and scalable.

With a market share of 44.48% in 2022, North America region led the aptamers market. The rising incidence of chronic diseases, the region's robust healthcare system, and the growing interest of research labs in the field of aptamers are some of the main drivers of the area's supremacy. Also in April 2022, Noxxon Pharma made the announcement that it would disclose top line results for its NOX-A12 GLORIA study in brain cancer at the annual meeting of the American Society of Clinical Oncology.

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Global Aptamers Market

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