USD 1.58 billion
Report ID: SQMIG35E2038 | Region: Global | Published Date: February, 2024 | Pages: 157 | Tables: 62 | Figures: 77
Aptamers Market size was valued at USD 1.58 billion in 2021 and is poised to grow from 1.99 USD billion in 2022 to USD 9.84 billion by 2030, at a CAGR of 25.69% during the forecast period (2023-2030).
Many researchers are interested in aptamers because of their competitive advantages in recent developments in the production, purification, and drug delivery for killing target cells. Small molecular size, low immunogenicity, low manufacturing costs, and less side effects compared to antibodies are a few of the benefits; these factors may encourage the development of innovative aptamers, leading to market expansion.
Due to several genetic variations, there are presently no extremely effective therapies for infections, despite extensive attempts. The SELEX technology-based diagnostic kits and assays have the capacity to produce high-affinity neutralizers. As a result, it is anticipated that the release of diagnostic kits on the market will spur market expansion. Aptamer is a second-generation diagnostic kit for healthcare that was created utilising DNA aptamer-based technology.
It is inexpensive, chemically synthesised, and a growing diagnostic kit. Soma Logic stated in March 2022 that it had begun employing the SomaScan Assay to analyse 210 million protein measurements from 30,000 samples for the European Prospective Investigation into Cancer and Nutrition (EPIC) research. Through a deeper understanding of the disease, researchers will be better able to forecast cancer, which will help the market flourish by meeting the growing demand.
Due to their tiny size, high specificity, selectivity, and efficacy, diagnostic solutions based on aptamers are the preferred option among diagnostic and pathology labs for the diagnosis of disease at the cellular level. Around 27.5 million individuals are anticipated to receive a cancer diagnosis by the year 2040, according to predictions from Cancer Research UK.
US Aptamers Market is poised to grow at a sustainable CAGR for the next forecast year.
Global Market Size
USD 1.58 billion
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Global Aptamers Market is segmented on the basis of type, application and region. By type, the market is segmented into nucleic acid and peptide. By application, market is segmented into diagnostics, therapeutics, research & development, others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Analysis by Type
The sector for nucleic acids had the most market share in 2022 (78.19%), and it is anticipated to increase at the fastest rate during the forecast period. The mechanism of action of nucleic acid aptamers for the treatment of various illnesses, such as age-related muscle degeneration (AMD), is now being studied by a large number of firms. For instance, the U.S. Food and Drug Administration (FDA) approved IVERIC BIO (previously Ophthotech Corporation) in writing under Special Protocol Assessment (SPA) for the design of the GATHER2 phase 3 clinical trial of Zimura for the treatment of individuals with GA secondary to AMD. This approval is anticipated to accelerate segment expansion.
Due to its wide range of therapeutic and diagnostic use, the peptide aptamer market is anticipated to expand at a lucrative CAGR of 22.77% between 2023 and 2030. As an illustration, researchers from the Engineering Centre for Microtechnology and Diagnostics created a new biosensor for multiparametric express testing in the preclinical diagnosis of cardiovascular disease. For this testing, the peptide aptamer marker system and molecular recognition have been used to construct next-generation biochips. Peptide aptamers have been created for this purpose utilizing information from Protein 3D and data from Data Bank. So, the availability of such goods could increase the use of peptide aptamers.
Analysis by Application
In 2022, the market share occupied by the research and development sector was 31.38%. The increase in research activities in this area and the rising demand for aptamers have created a market for them in the field of research and development, which is what is responsible for the segment's rise. Key actors have engaged in a variety of strategic efforts, such as joint ventures, partnerships, and agreements for the research and development of innovative aptamer-based diagnostic and therapeutic products.
The therapeutics market is predicted to grow at a lucrative rate between 2023 and 2030, with a CAGR of 26.08%, thanks to the ability to rationally design antidotes (which is difficult with antibodies). It is also regarded as the superior option compared to protein therapeutics in terms of synthetic accessibility, size, and medicinal chemistry modification. All of these facts work together to support the therapeutics market segment's efforts to establish a solid presence in the coming years. The segment expansion, however, can be constrained by nuclease resistance, a significant concern connected to therapeutic aptamers.
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With a market share of 44.48% in 2022, North America region led the aptamers market. The rising incidence of chronic diseases, the region's robust healthcare system, and the growing interest of research labs in the field of aptamers are some of the main drivers of the area's supremacy. Also in April 2022, Noxxon Pharma made the announcement that it would disclose top line results for its NOX-A12 GLORIA study in brain cancer at the annual meeting of the American Society of Clinical Oncology.
The market for aptamers in Asia Pacific is anticipated to expand at the quickest rate, with a CAGR of 26.18%. The region's growth is attributable to the acceptance of new aptamer-based products in the area. For instance, Achiko AG signed a contract with the Pengurus Wilayah Nahdlatul Ulama DKI, the largest Islamic organization in the world with headquarters in Jakarta, for the marketing and distribution of Aptamer, a COVID-19 diagnostic kit based on aptamers. In Indonesia, this organization has 90 million registered members.
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Increasing Demand for Personalized Medicine
Advantages over Traditional Antibodies
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To increase their market share, major players are using tactics including product modification, new product approval, mergers and acquisitions, and geographical growth. These methods are all aimed at improving their current products. Applications of aptamers in therapeutics may find new growth opportunities as a result of such activities.
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SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.
According to our analyses, the global aptamers market is poised for significant growth and holds immense potential for various applications in diagnostics, therapeutics, and research. The global aptamers market has been experiencing steady growth in recent years. The market size is expected to reach billions of dollars by the end of the forecast period. Aptamers have emerged as valuable tools in diagnostic applications. They offer advantages such as high specificity, sensitivity, and rapid binding kinetics, making them ideal for detecting disease biomarkers, pathogens, and other analytes. Aptamer-based diagnostic platforms are gaining popularity due to their ability to provide accurate and rapid test results. The aptamers market is witnessing continuous technological advancements. Researchers are exploring innovative aptamer selection techniques, modifications, and delivery systems to enhance their properties and broaden their application scope. Advances in high-throughput screening, automation, and nanotechnology are driving the development of more efficient and specific aptamers.
|Market size value in 2021
|USD 1.58 billion
|Market size value in 2030
|USD 9.84 billion
|Forecast Unit (Value)
|North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
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For the Global Aptamers Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Global Aptamers Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
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