USD 17.27 billion
Report ID:
SQMIG25AD2013 |
Region:
Global |
Published Date: February, 2025
Pages:
197
|Tables:
92
|Figures:
71
Antipsychotic Drugs Market size was valued at USD 17.27 billion in 2023 and is poised to grow from USD 18.27 billion in 2024 to USD 28.69 billion by 2032, growing at a CAGR of 5.8% during the forecast period (2025-2032).
Awareness about mental health problems is one of the main reasons behind the growing demand for global antipsychotic drugs market. Governments, NGOs, and other health organizations are focusing on promoting education regarding mental health and raising awareness to increase early diagnosis and treatment.
The global antipsychotic drugs market is experiencing steady growth, resulting of an increase in mental health disorders, including schizophrenia, bipolar disorder, and major depressive disorder. Medications that constitute the antipsychotic group include first-generation, or typical, and second-generation, or atypical drugs, which play a vital role in controlling hallucinations, delusions, and cognitive impairments caused by psychiatric illnesses.
The market is expanding due to increased awareness of the issues of mental health, growing government initiatives to better psychiatry care, and increasing investments in drug development. There is an upswing in innovative LAIs as they promote patient adherence and resultant treatment outcomes compared to traditional oral tablets. The developments in pharmacogenomics and personalized medicine are also molding the global antipsychotic drugs market trends as they allow more targeted therapies with fewer side effects. The research is ongoing into new mechanisms of action, including glutamate receptor modulators and dopamine system stabilizers, which continues to drive the industry forward in innovation.
The global antipsychotic drugs market overview is experiencing several key trends that are reshaping the landscape. The most significant driving factor in this market is the rising preference toward atypical antipsychotics, with improved safety profiles and reduced extrapyramidal side effects compared to first-generation drugs. Another trend in revolutionizing treatment approach is the emergence of digital therapeutics and AI-driven drug development, allowing for real-time data-driven insights into patient behavior, medication adherence, and early symptom detection.
Combination therapies have emerged as a very important trend wherein antipsychotics are combined with mood stabilizers, antidepressants, or cognitive enhancers to improve treatment efficacy. There is an increased demand for over the counter and alternative formulations such as transdermal patches and sublingual films due to improved patient compliance. The pharmaceutical industries are currently indulging in research collaborations and strategic mergers as a part of their effort towards improving their discovery capabilities, introducing new products for the markets, and expanding presence in markets. With rising spending on mental disorder research, drugs approval regulations of regulatory agencies is also expected to be improved within the near term, leading towards faster development in the new year’s.
Key Market Attributes
In January 2025, Johnson & Johnson announced its $15 billion acquisition of Intra-Cellular Therapies to expand its neuroscience portfolio. This strategic move brings Caplyta, a key drug for bipolar depression and schizophrenia, into J&J’s product line. Caplyta has shown strong market potential, with analysts projecting annual sales of $4 billion by 2030. The acquisition strengthens J&J’s presence in the global antipsychotic drugs market, allowing it to compete more effectively with industry leaders. With rising demand for innovative psychiatric treatments, this deal positions J&J for significant growth in the next five years, particularly in long acting and targeted therapies.
In September 2024, Bristol Myers Squibb received FDA approval for Cobenfy (KarXT), a next-generation schizophrenia treatment acquired through its $14 billion takeover of Karuna Therapeutics. Unlike traditional antipsychotics, Cobenfy offers symptom relief with fewer side effects, addressing a major concern in psychiatric care. Analysts expect the drug to generate billions in U.S. sales by 2030, reinforcing Bristol Myers Squibb’s leadership in the global antipsychotic drugs market. With increasing demand for safer and more effective treatments, the approval of Cobenfy is expected to drive innovation and competition, shaping the industry’s future over the next four to five years.
In October 2023, Reviva Pharmaceuticals reported positive Phase III RECOVER trial results for brilaroxazine, a novel antipsychotic that targets multiple serotonin receptors. Brilaroxazine demonstrated significant improvements in both positive and negative schizophrenia symptoms while maintaining a favorable safety profile. Brilaroxazine is a new mechanism that could reduce common side effects such as weight gain and sedation compared to traditional antipsychotics. Pending the approval of the FDA and other regulatory agencies, this future drug may change the treatment of schizophrenia in the following decade. It could also further some other multi-receptor-targeting research, and it may lead to generations of safer and more effective antipsychotic drugs worldwide.
In April 2024, The FDA approved ultra innovative schizophrenia medicine developed by Japan's Sumitomo Pharma, and Otsuka Pharmaceutical with a new active ingredient. A difference between classic antipsychotics and these medicines is they do not address dopamine receptors: This reduces associated risks of a movement disorder - among the side effects most typical for antipsychotics of all types-and also other severe side effects related to this pathway. Over the next decade, approval of ulotaront is likely to dramatically alter prescribing patterns, which in turn could pressure the industry toward new drug development. Success would likely stimulate more research into non-dopaminergic pathways and transform the landscape of schizophrenia treatment around the world.
Market snapshot - 2025-2032
Global Market Size
USD 17.27 billion
Largest Segment
Schizophrenia
Fastest Growth
Bipolar Disorder
Growth Rate
5.8% CAGR
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Global Antipsychotic Drugs Market is segmented by Therapeutic Class, Disease, Drug, Distribution Channel and region. Based on Therapeutic Class, the market is segmented into First Generation, Second Generation and Third Generation. Based on Disease, the market is segmented into Schizophrenia, Bipolar Disorder, Unipolar Depression, Dementia and Other Diseases. Based on Drug, the market is segmented into Risperidone, Quetiapine, Olanzapine, Aripiprazole, Brexpiprazole, Paliperidone Palmitate and Others. Based on Distribution Channel, the market is segmented into Hospital Pharmacies, Drug Stores & Retail Pharmacies and Online Pharmacies. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.
Analysis by Disease
As per categorization by disease, the market is classified as schizophrenia, bipolar disorder, dementia, unipolar depression, and other diseases. Among these, schizophrenia earned the largest share and continues to hold the dominant global antipsychotic drugs market share. Schizophrenia is the most prevalent disorder and continues to be a leading focus in the global antipsychotic drugs market. The current innovations are focused on the development of drugs with fewer side effects, such as brilaroxazine and ulotaront, which target multiple neurotransmitter systems. Schizophrenia's impact on patients' daily lives and its chronic nature drives continuous demand for more effective therapies. As schizophrenia represents the foremost psychiatric disorder as regards treatment burden, its primacy determines what happens in drug development and markets as well.
Bipolar disorder is poised to become the fastest-growing segment in the global antipsychotic drugs market due to its rising global prevalence and the increasing recognition of its impact on individuals’ mental health. Bipolar disorder, an illness with extreme mood variations, will push the need for successful therapies that can treat both maniacal and depressive episodes. Recent advancements in mood stabilizers and atypical antipsychotics combined with high concerns over early diagnosis and individualized treatments are likely to fuel this market growth. As awareness about bipolar disorder improves and more individuals begin to seek treatment, this sector is bound to experience exponential growth over the next few years.
Analysis by Therapeutic Class
Second-generation antipsychotics (SGAs) are currently driving innovation in the global antipsychotic drugs market due to their improved efficacy and safety profiles compared to first-generation drugs. These drugs are preferred as the risk of occurrence of extrapyramidal symptoms and cognitive side effects is very low, meaning better compliance for the patient, and innovations have been made through long acting injectables, novel formulations with SGAs further enhancing their use. Market leadership is conferred to these agents by the strengths described above plus increased demand from the marketplace seeking more tolerable therapies, therefore more use of them in cases such as schizophrenia and bipolar disease.
Third-generation antipsychotics are poised to be the fastest-growing segment in the global antipsychotic drugs market due to their targeted approach and minimal side effects. Unlike other previous generations, the third generation of antipsychotics, with aripiprazole among them, have the ability to modulate the dopamine receptors without causing any appreciable sedation or weight gain. Such agents provide better clinical outcomes in patient care, mainly in treating the symptoms of schizophrenia and bipolar disorders. With this potential to also improve cognitive performance and decrease unwanted side effects, these agents appear to be in high demand from both patients and clinicians alike and are gaining increased market share fast.
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As per the global antipsychotic drugs market analysis, North America dominates the industry due to its advanced healthcare infrastructure, high demand for mental health treatments, and substantial pharmaceutical investments. Extensive research and development, and a robust access market and a sound regulatory framework have been aiding the growth in innovative antipsychotic therapies for the region. This is it guys we are home.
The U.S. market, primarily driven by a growing sense of awareness about and destigmatization of mental health issues that results in the increase in the rate of seeking treatments, witnessed higher demand in the advanced class of antipsychotic drugs with increased coverage through insurance on psychiatric care; therefore, a larger share goes to the United States.
The antipsychotic drugs market is the fastest-growing region in Europe due to an increase in mental health awareness, easy access to treatment, and growing investments in psychiatric care. Furthermore, Europe's aging population and increasing prevalence of mental disorders are driving demand for advanced antipsychotic therapies.
One of the key driving factors in the European antipsychotic drugs market is Germany, with a strong healthcare system and progressive policies on mental health. Government-aided initiatives for mental health, along with growing research about innovative treatments, contribute to rising demand for these medications, therefore making Germany one of the critical players in market growth in that region.
The Asia-Pacific is the fastest growing region in the global antipsychotic drugs market and this growth stems from a surging population base, rising mental health awareness, and enhanced governmental investment in the healthcare infrastructure of the region. As psyche-related problems surface, demand increases for proper remedial measures concerning schizophrenia and other bipolar disorder type conditions. Besides, increasing access to healthcare in the emerging economies along with innovative antipsychotic therapies is driving market expansion in Japan, China, and India.
The Middle East and Africa (MEA) region is witnessing steady growth in the global antipsychotic drugs market, driven by rising awareness of mental health issues and increasing healthcare investments. While there remain areas where there is limited access to mental health care in the region, improvements in health care infrastructure along with expanding coverage under insurance will help improve treatment access. Also, increased diagnosis of mental disorders in Saudi Arabia, UAE, and South Africa is also supporting the demand for antipsychotic drugs.
Antipsychotic medications are finding more use in South America with continuous growth. Reasons include improved knowledge about mental disorders, easier healthcare access, and increasing concern toward psychiatric disorder therapies. For Brazil and Argentina, public as well as private initiative by healthcare service providers increase a greater demand for sophisticated antipsychotic medications. Despite that, it does have drawbacks related to scarce psychiatric professionals and also inequality among other regions for equal access to medical services. Despite these barriers, the demand for effective antipsychotic medications continues to rise across the region, as per the global antipsychotic drugs market outlook.
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Antipsychotic Drugs Market Drivers
Rising Prevalence of Mental Health Cases
Advancement of Drug Formulations
Antipsychotic Drugs Market Restraints
Regulatory Hurdles and Lengthy Approval Processes
Stigma Surrounding Mental Health Disorders
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The global antipsychotic drugs market is highly competitive, with key players focusing on innovation, drug development, and expanding their portfolios. These well-established drugs include leading players in the market: Johnson & Johnson, Eli Lilly, Otsuka Pharmaceutical, and AstraZeneca. They keep pouring significant investment in research and development to provide a better cure that can serve in the future-advanced treatment including long-acting injectables, third-generation antipsychotics, for those suffering from psychiatric disorders in higher numbers.
Top Player’s Company Profiles
Recent Developments
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As per SkyQuest analysis, the global antipsychotic drugs industry is seeing growth at a phenomenal rate driven by increasing mental health awareness, a growing incidence of mental health disorders, and new drug development. The global antipsychotic drugs market is gaining traction as long acting injectables improve, and there is increased interest in combination therapies to optimize outcomes for patients.
Another push factor for expansion is new drug treatments for conditions like schizophrenia and bipolar disorder as well as others, where various companies are actively investing in new research and the strategic acquisition of other firms for portfolio expansion. The market for psychiatric care should continue to increase with new and innovative drugs amid the continued elimination of stigma concerning mental health care.
Report Metric | Details |
---|---|
Market size value in 2023 | USD 17.27 billion |
Market size value in 2032 | USD 28.69 billion |
Growth Rate | 5.8% |
Base year | 2024 |
Forecast period | 2025-2032 |
Forecast Unit (Value) | USD Billion |
Segments covered |
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Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
Companies covered |
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Table Of Content
Executive Summary
Market overview
Parent Market Analysis
Market overview
Market size
KEY MARKET INSIGHTS
COVID IMPACT
MARKET DYNAMICS & OUTLOOK
Market Size by Region
KEY COMPANY PROFILES
Methodology
For the Antipsychotic Drugs Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Antipsychotic Drugs Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
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With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Antipsychotic Drugs Market:
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Global Antipsychotic Drugs Market size was valued at USD 15.12 Billion in 2023 poised to grow from USD 16.33 Billion in 2024 to USD 30.22 Billion by 2032, growing at a CAGR of 8% in the forecast period (2025-2032).
The global antipsychotic drugs market is highly competitive, with key players focusing on innovation, drug development, and expanding their portfolios. These well-established drugs include leading players in the market: Johnson & Johnson, Eli Lilly, Otsuka Pharmaceutical, and AstraZeneca. They keep pouring significant investment in research and development to provide a better cure that can serve in the future-advanced treatment including long-acting injectables, third-generation antipsychotics, for those suffering from psychiatric disorders in higher numbers. 'Johnson & Johnson (USA)', 'Eli Lilly and Co. (USA)', 'AstraZeneca (UK/Sweden)', 'Otsuka Pharmaceutical (Japan)', 'Pfizer Inc. (USA)', 'Sanofi (France)', 'Novartis (Switzerland)', 'Roche (Switzerland)', 'Merck & Co., Inc. (USA)', 'H. Lundbeck A/S (Denmark)', 'Sumitomo Dainippon Pharma Co. (Japan)', 'Teva Pharmaceutical Industries Ltd. (Israel)', 'Mylan N.V. (USA)', 'AbbVie Inc. (USA)', 'Bristol-Myers Squibb (USA)'
One key driver of the global antipsychotic drugs market growth is the rising prevalence of mental health disorders, including schizophrenia and bipolar disorder. With increasing awareness and recognition of such conditions, both the innovation of therapies and a need for access to psychiatric care are becoming increased demands in virtually every part of the world.
Rising Demand for Long-Acting Injectable Antipsychotics: One of the recent trends noticed in the global antipsychotic drugs market is growing demand for long-acting injectable antipsychotics. Long-acting formulations are a type of preparation that allows reduction of dosing frequency, resulting in better chronic psychiatric disorder management like schizophrenia in patients. There has been development in innovative injectables by various companies to overcome patient need for sustained efficacy with the convenience factor.
As per the global antipsychotic drugs market analysis, North America dominates the industry due to its advanced healthcare infrastructure, high demand for mental health treatments, and substantial pharmaceutical investments. Extensive research and development, and a robust access market and a sound regulatory framework have been aiding the growth in innovative antipsychotic therapies for the region. This is it guys we are home.
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Report ID: SQMIG25AD2013
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