Global Active Ingredients Market

Active Ingredients Market Size, Share, Growth Analysis, By Synthesis(Synthetic and Biotech), By Application(Cardiology, Pulmonology, Oncology, Ophthalmology), By Business Mode(Captive API and Merchant API), By Brand(Patented/ Innovative API and Generic API), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35A2875 | Region: Global | Published Date: April, 2024
Pages: 218 |Tables: 115 |Figures: 74

Active Ingredients Market Insights

Global Active Ingredients Market size was valued at USD 224.56 Billion in 2022 and is poised to grow from USD 237.47 Billion in 2023 to USD 371.41 Billion by 2031, growing at a CAGR of 5.75% in the forecast period (2024-2031).

Increasing consumer trends towards personal grooming and cosmetics are driving demand for active ingredients in skin care, hair care, color and cosmetics. Increasing disposable income, urbanization and changing lifestyles are contributing to the expanding market for active ingredients in the personal care and cosmetics industry. Technological advances and innovations in the pharmaceutical industry led to the development of new drugs and treatments that require the use of active ingredients (APIs). The demand for high-quality and efficient APIs is driving investment in research and development, driving market growth in the pharmaceutical industry.

The number of elderly people worldwide is increasing. According to the United Nations, there are expected to be 771 million people aged 65 and older in the population by 2022, rising from 994 million in 2030 to 1.6 billion in 2050. The number of older people in Africa shows the fastest growth rate, also including those aged 60 and over. The population is projected to triple, followed by Latin America to 18.8 billion by 2050. Growth is viewed as high risk of developing diseases including cardiovascular diseases hence rapidly increasing global elderly population could be a major confirmatory influence for the global active ingredients market.

Market Snapshot - 2024-2031

Global Market Size

USD 224.56 Billion

Largest Segment

Cardiology

Fastest Growth

Oncology

Growth Rate

5.75% CAGR

Global Active Ingredients Market ($ Bn)
Country Share for North America Region (%)

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Active Ingredients Market Segmental Analysis

By synthesis, the active pharmaceutical ingredients market is classified into synthetic and biotech. By application, the global market is divided into many segments such as cardiology, pulmonology, oncology, ophthalmology, neurology, orthopedic, and other applications. By brand the market is segmented into patented/ innovative API and generic API. By business mode, the market is segmented into captive API and Merchant API. Geographically, the Global Active Ingredients Market has been segmented into Asia-Pacific, North America, Europe, and the Middle East & Africa, and South America.

Analysis by Application

The cardiology segment dominated the global active ingredients market in terms of revenue share in 2023 attributed to rising cardiovascular diseases across the globe. According to the World Heart Report 2023, more than half a billion people worldwide are affected by CVD, causing approximately 20.5 million deaths by 2021 nearly a third of global deaths and an increase of more than 100,000 121 million previously estimated CVD deaths spurred mass research on the topic. Simvastatin is a lipid-lowering drug that belongs to the statin class and is used to treat lipodystrophy. Rosuvastatin calcium is a new API used by AstraZeneca for cardiovascular diseases.

The oncology segment is expected to grow the fastest during the forecast period. The increasing incidence of cancer worldwide is a major driver of this market. Collaboration between pharmaceutical companies, research institutes, and regulatory agencies is critical to accelerate drug development, ensure patient safety, & drive innovation. For example, in March 2023, Pfizer Inc. will have 100,000 shares and CGen Inc. confirmed that a definitive union agreement had been reached. Through this strategic deal, Pfizer will acquire CGen, a leading biotechnology company that develops revolutionary cancer therapies. The deal includes a trading denomination of U.S. dollars. $229 per CGen share, giving it an enterprise value of US$229. $43 billion has been generated.

Analysis by Type

The patented/innovative API segment dominated the overall global active ingredients market by revenue share by 2023. The growth of the market is driven by increase in funding and better regulation for R&D facilities due to extensive research on this industry therefore, there are currently many new innovative products, and it is anticipated that it will be established soon. Furthermore, support from regulatory bodies for approval of new drugs is expected to facilitate incremental market growth, which can be attributed to increased government attention to healthcare and drugs.

The generic APIs segment is expected to show the fastest growth during the forecast period. The expiry of patents on pharmaceutical branded molecules is a key driver of great opportunities for the development of generic pharmaceutical Apis. The post-pandemic pharmaceutical industry has moved to aggressive patents by 2030, with a loss of almost 200 molecules alone and more than 100 biosimilars by 2023. This presents an opportunity for developers of generic APIs as API demand for these products is set to increase by the end of this decade. It includes more than 60 molecules that cover the oncology segment with strong API’s that generate significant revenue.

Global Active Ingredients Market By Application (%), 2022 (%)

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Active Ingredients Market Regional Insights

North America led the global active ingredients market to account for 38.26% share by 2023 as rising incidence of cardiac, genetic, and other chronic diseases contributed to increased research in pharmaceuticals. AbbVie Inc. the availability of specialized services such as; Kuria; Pfizer Inc. (Pfizer One Institute); Viatris Inc., Fresenius Kaby AG was having a positive impact on growth. For example, in February 2022, Viatris received FDA approval for generic Restasis—a cyclosporine eye drops for the treatment of cataracts.

Asia Pacific is slated to expand at the fastest pace during the forecast years. The market is growing rapidly as most of the API production takes place in the countries in the region with high levels of API exports. China is the largest producer of APIs, producing more than 1600 types of pharmaceutical APIs and moreover, they are especially many Global players are setting up their activities in this area. Increasing investments and infrastructure to support and expand manufacturing facilities are going to drive the overall growth of the global active ingredients market.

Global Active Ingredients Market By Geography, 2024-2031
  • Largest
  • Fastest

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Active Ingredients Market Dynamics

Drivers

Growing Demand for Functional Nutrients

  • Increased consumer awareness of the relationship between food and health is driving demand for active ingredients and nutritional value in food, beverages and nutritional supplements. Active ingredients such as vitamins, minerals, antioxidants and plant extracts are being studied for potential health benefits, including immunity, mental health and anti-aging.

Growing Aging and Health Problems

  • The global demographic shift towards an older population is providing practical applications for pharmaceutical, nutritional and personal care products targeting age-related health concerns the demand for self-sufficiency has increased. Active ingredients with anti-inflammatory, anti-inflammatory and skin-rejuvenating properties are sought to combat age-related conditions such as arthritis, cardiovascular diseases and skin more about growth.

Restraints

Price Fluctuations in Emerging Nations to Restrict Market Growth

  • The periodic and unanticipated changes inside the pricing rules of drugs inside the emerging areas, in which most of the producing organizations are located, is predicted to avoid the marketplace growth all through the forecasted length. Dependency of the advanced regions for the manufacturing of energetic elements on China has led to unforeseen changes inside the pricing policy of China. This is projected to have a negative effect on the overall boom of this market.

Concerns about Pharmaceutical Pricing Restricting Market Growth

  • Direct or indirect restrictions on reimbursement or benefits help most states control physician prices. Many large countries in the world have unregulated pharmaceutical markets that cause price fluctuations and can restrict market growth. In some countries, governments have limited spending on pharmaceuticals, which in turn reduces R&D costs and produces fewer new molecule companies each year.

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Active Ingredients Market Competitive Landscape

The competitive environment of the Global Active Ingredients Market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. Companies compete based on innovation and differentiation, developing functional innovations that improve performance, safety specifications and durability certifications. Investing in research and development (R&D) is essential to stay ahead in the competitive environment, as consumers demand products with scientifically validated ingredients and unique ingredients. Collaborations between manufacturers, research institutes and academic institutions foster innovation and accelerate product development in the materials market. Strategic partnerships enable companies to acquire complementary technologies, share resources, and leverage expertise to meet evolving customer preferences and market trends.

Top Player’s Company Profiles

  • Sanofi S.A.
  • Merck & Co., Inc.
  • Boehringer Ingelheim GmbH
  • GlaxoSmithKline plc
  • AstraZeneca plc
  • Bristol-Myers Squibb Company
  • AbbVie Inc.
  • Eli Lilly and Company
  • BASF SE
  • Lonza Group Ltd.
  • Cambrex Corporation
  • Dr. Reddy's Laboratories Ltd.
  • Sun Pharmaceutical Industries Ltd.
  • Lupin Limited
  • Cadila Healthcare Ltd.
  • Cipla Ltd.
  • Aurobindo Pharma Limited

Recent Developments

  • In August 2023, EuroAP announced an agreement to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, a high-growth business.
  • In July 2023, Teva Pharmaceutical Industries Limited developed a new development plan to market its API unit on the table. The API industry is worth $2 billion.
  • In April 2023, Eli Lilly announced a $1.6 billion (about $5 per person in the US) investment in the LEAP Innovation Park in the US. in the 19th century. This makes all investments in developing robust APIs for products like gene therapy US-based.

Active Ingredients Key Market Trends

Rising Demand for Active Ingredients with Multifunctional Properties

  • Multifunctional active ingredients in the pharmaceutical industry can provide therapeutic effects and other benefits such as prolonged release or improved bioavailability. Multifunctional active ingredients in the personal care and cosmetic industry can provide moisture, anti-aging and UV protective properties in one product. In agriculture, multifunctional materials can provide antimicrobial and plant growth-promoting properties, reducing the need for multiple applications and increasing overall yield and health. This trend is driven by factors such as consumer demand for simpler and more efficient products, lower costs for manufacturers, and regulatory pressures to reduce the number of ingredients used in pharmaceutical manufacturing.

Active Ingredients Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

The global active ingredients market covers the manufacture, distribution and application of active ingredients in various industries such as pharmaceutical, personal care, agriculture and household appliances. Active ingredients are pharmaceutical compounds which handle products ranging from pharmaceuticals and cosmetics to pesticides and detergents.

The global market witnessed a steady growth, driven by factors such as rising population, increased health awareness, demand for cosmetics and personal care products high, expanded agricultural activities to meet food demand affect these factors. The innovation in technological reagents has led to the development of safe, effective and environmentally friendly chemicals in order to reduce and monitor environmental footprint recognizing the safety of the products, manufacturers are increasingly focusing on green chemistry principles and sustainable manufacturing practices. Advanced techniques such as biotechnology, nanotechnology and synthetic biology are being used to discover and develop new functional materials with improved properties and properties.

Report Metric Details
Market size value in 2022 USD 224.56 Billion
Market size value in 2031 USD 371.41 Billion
Growth Rate 5.75%
Base year 2023
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Synthesis
    • Synthetic and Biotech
  • Application
    • Cardiology, Pulmonology, Oncology, Ophthalmology, Neurology, Orthopedic, and Other Applications
  • Business Mode
    • Captive API and Merchant API
  • Brand
    • Patented/ Innovative API and Generic API
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Sanofi S.A.
  • Merck & Co., Inc.
  • Boehringer Ingelheim GmbH
  • GlaxoSmithKline plc
  • AstraZeneca plc
  • Bristol-Myers Squibb Company
  • AbbVie Inc.
  • Eli Lilly and Company
  • BASF SE
  • Lonza Group Ltd.
  • Cambrex Corporation
  • Dr. Reddy's Laboratories Ltd.
  • Sun Pharmaceutical Industries Ltd.
  • Lupin Limited
  • Cadila Healthcare Ltd.
  • Cipla Ltd.
  • Aurobindo Pharma Limited
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Active Ingredients Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Active Ingredients Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Active Ingredients Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Active Ingredients Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Active Ingredients Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Active Ingredients Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Active Ingredients Market size was valued at USD 224.56 Billion in 2022 and is poised to grow from USD 237.47 Billion in 2023 to USD 371.41 Billion by 2031, growing at a CAGR of 5.75% in the forecast period (2024-2031).

The competitive environment of the Active Ingredients Market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. Companies compete based on innovation and differentiation, developing functional innovations that improve performance, safety specifications and durability certifications. Investing in research and development (R&D) is essential to stay ahead in the competitive environment, as consumers demand products with scientifically validated ingredients and unique ingredients. Collaborations between manufacturers, research institutes and academic institutions foster innovation and accelerate product development in the materials market. Strategic partnerships enable companies to acquire complementary technologies, share resources, and leverage expertise to meet evolving customer preferences and market trends. 'Sanofi S.A.', 'Merck & Co., Inc.', 'Boehringer Ingelheim GmbH', 'GlaxoSmithKline plc', 'AstraZeneca plc', 'Bristol-Myers Squibb Company', 'AbbVie Inc.', 'Eli Lilly and Company', 'BASF SE', 'Lonza Group Ltd.', 'Cambrex Corporation', 'Dr. Reddy's Laboratories Ltd.', 'Sun Pharmaceutical Industries Ltd.', 'Lupin Limited', 'Cadila Healthcare Ltd.', 'Cipla Ltd.', 'Aurobindo Pharma Limited'

Increased consumer awareness of the relationship between food and health is driving demand for active ingredients and nutritional value in food, beverages and nutritional supplements. Active ingredients such as vitamins, minerals, antioxidants and plant extracts are being studied for potential health benefits, including immunity, mental health and anti-aging.

Multifunctional active ingredients in the pharmaceutical industry can provide therapeutic effects and other benefits such as prolonged release or improved bioavailability. Multifunctional active ingredients in the personal care and cosmetic industry can provide moisture, anti-aging and UV protective properties in one product. In agriculture, multifunctional materials can provide antimicrobial and plant growth-promoting properties, reducing the need for multiple applications and increasing overall yield and health. This trend is driven by factors such as consumer demand for simpler and more efficient products, lower costs for manufacturers, and regulatory pressures to reduce the number of ingredients used in pharmaceutical manufacturing.

North America led the active ingredients market to account for 38.26% share by 2023 as rising incidence of cardiac, genetic, and other chronic diseases contributed to increased research in pharmaceuticals. AbbVie Inc. the availability of specialized services such as; Kuria; Pfizer Inc. (Pfizer One Institute); Viatris Inc., Fresenius Kaby AG was having a positive impact on growth. For example, in February 2022, Viatris received FDA approval for generic Restasis—a cyclosporine eye drops for the treatment of cataracts.

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