Preparative and Process Chromatography Market Size

Preparative and Process Chromatography Market Insights

Preparative and Process Chromatography Market size was valued at USD 10.4 billion in 2023 and is poised to grow from USD 11.68 billion in 2024 to USD 29.54 billion by 2032, growing at a CAGR of 12.3% during the forecast period (2025-2032).

Large-scale integration of liquid chromatography techniques in downstream processing has accelerated the growth of this field. technological development, and high demand for preparative techniques have all played a role. Throughout the forecast period, monoclonal antibodies are forecast to be more in demand and being accepted for use in the pharmaceutical and biotechnology sectors.

This is explained by the greater involvement of service providers in chromatographic-based antibody separation methods including affinity chromatography and column displacement chromatography. Chromatography is a process that is used for separating constituents or solutes of a mixture based on the relative quantities of each solute dispersed between a moving fluid stream, known as the mobile phase, and a contiguous stationary phase.

The method of preparative chromatography is used to separate components of complicated mixtures. It is used in the pharmaceutical industry to free molecules of impurities before they are purified and used for a range of tasks, with clinical supply in the case of active medicinal components.

Process chromatography is an analytical technique that allows online mixture component separation and quantification in a chemical process. By obtaining a set number of samples, separating the chemical components using adsorption or partitioning columns, and then determining the concentration of each component using a detector, on-line chromatograph analyzers can work continuously and automatically.

US Preparative and Process Chromatography Market is poised to grow at a sustainable CAGR for the next forecast year.

FAQs

Preparative and Process Chromatography Market size was valued at USD 9.96 Billion in 2023 and is poised to grow from USD 11.13 Billion in 2024 to USD 26.98 Billion by 2032, growing at a CAGR of 11.7% during the forecast period (2025-2032).

Players in the global market are investing in R&D activities to stay ahead in the competition. Players are also focusing on merger & acquisition to expand their consumer base. 'Agilent Technologies, Inc.', 'GE Healthcare Life Sciences', 'Merck KGaA', 'Danaher Corporation', 'Waters Corporation', 'Shimadzu Corporation', 'Bio-Rad Laboratories, Inc.', 'Thermo Fisher Scientific, Inc.', 'Novasep Holding S.A.S.', 'Knauer GmbH', 'Chiral Technologies, Inc.', 'Kromasil AB', 'PALL Corporation', 'Mitsubishi Chemical Corporation', 'YMC Co., Ltd.', 'ACE Chemicals (Tianjin) Co., Ltd.', 'GL Sciences, Inc.', 'Sepax Technologies, Inc.', 'PhyNexus, Inc.', 'GL Sciences Inc.', 'In 2021, The Waters Arc Premier System, designed for chromatographic separations on 2.5 to 3.5 micron columns, was introduced by Waters.', 'In 2021, Sartorius and Novasep A contract was made by Stedim Biotech selling Sartorius the former business's chromatography equipment segment. By partnering with a proven leader in the industry, Novasep will be able to accelerate the growth of its chromatography division.'

Revenue growth in the global chromatography technique is driven by a wide range of growing applications, and this technique can provide an exact separation and purification which can be achieved with this technique. This technique uses a process called chromatography to separate a very small amount (often parts per million) of the multiple component mixtures. This aids the analyst in quantitative determination of components of mixtures. Increasing application of chromatography due to such advantages is expected to increase revenue growth of the market.

According to the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA), pharmaceutical entities spend nearly USD 149.8 Bn every year on research, thereby supporting the research that is going on in the preparative and process chromatography market. Such research is contributing to the economic growth of the market. Moreover, numerous advancements in this market have created extensive demand and prevented due growth. FPLC (Fast Protein Liquid Chromatography) is being used for purifying biomolecules (say – proteins).

North America captured the largest revenue share of 32.11% in 2021. The regional market is growing because there are a lot of key players, and the companies are investing in research and development to manage diseases. The United States is a major player in regional market growth because it is investing more in R&D. This is being done by both private and public entities.